Frequency and prognostic evaluation of 3p21‐22 allelic losses in non‐small‐cell lung cancer

International Journal of Cancer

Volumn 64, Issue 6, 1995, Pages 371-377

  Thiberville, Luc ^a,b,c   Bourguignon, Jeannette ^a,c   Metayer, Josette ^b   Bost, Frederic ^a   Diarra‐Mehrpour, Maryam ^a,c   Bignon, Jean ^d   Lam, Stephen ^e   Martin, Jean‐Pierre ^a,c   Nouvet, Georges ^b,c  

^a INSERM   (France)

^b ROUEN UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE ROUEN   (France)

^d CENTRE HOSPITALIER INTERCOMMUNAL DE CRÉTEIL   (France)

^e BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; CHROMOSOME 3P; CHROMOSOME LOSS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ALLELES; BASE SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CHROMOSOMES, HUMAN, PAIR 3; GENE DELETION; GENETIC MARKERS; HETEROZYGOTE; HUMANS; LUNG NEOPLASMS; MICROSATELLITE REPEATS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; RESTRICTION MAPPING;

EID: 0029572414     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.2910640604     Document Type: Article

References (36)

1. Pathology of lung cancer
2. Detection of loss of heterozygosity in formalin‐fixed paraffin‐embedded tumor specimens by the polymerase chain reaction
3. Isolation and characterization of the human inter‐alpha‐trypsin‐inhibitor heavy‐chain H1 gene
4. Molecular analysis of the short arm of chromosome 3 in small‐cell and non‐small‐cell carcinoma of the lung
5. Molecular mapping of chromosome‐3p‐deletion sites in human lung cancer
6. A. homozygous deletion on chromosome 3 in a small‐cell‐lung‐cancer cell line correlates with a region of tumor‐suppressor activity
7. Tandem orientation of the inter‐α‐trypsin‐inhibitor heavy‐chain H1 and H3 genes
8. Human plasma inter‐alpha‐trypsin inhibitor is encoded by four genes on three chromosomes
9. Microsatellite instability and other molecular abnormality in non‐small cell lung cancer
10. PCR‐based RFLP analysis allows genotyping of the short arm of chromosome 3 in small biopsies from patients with lung cancer
11. Prognostic significance of p53 mutations and 3p deletions in primary resected non‐small‐cell lung cancer
12. Detailed deletion mapping of the short arm of chromosome 3 in small‐cell and non‐small‐cell carcinoma of the lung
13. Allele‐specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma
14. Restriction‐length‐polymorphism studies show consistent loss of chromosome 3p alleles in small‐cell‐lung‐cancer patient's tumors
15. Isolation and characterization of 19 dinucleotide repeat polymorphisms on chromosome 3p
16. Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer
17. A homozygous deletion in small‐cell‐lung‐cancer cell line involving a 3p21 region with a marked instability in yeast chromosomes
18. Consistent chromosome 3p deletion and loss of heterozygosity in renal‐cell carcinoma
19. Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas
20. Detection of dysplasia and carcinoma in situ with a lung‐imaging fluorescence endoscope device
21. Sstl RFLP in the human inter‐a‐trypsin‐inhibitor heavy‐chain gene
22. Three discrete regions of deletion at 3p in head and neck cancers
23. Microsatellite alterations as clonal markers for the detection of human cancer
24. Definition of a tumor‐suppressor locus within human chromosome 3p21‐p22
25. Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction
26. Mutation of a mutL homolog in hereditary colon cancer
27. Microsatellite instability is associated with tumors that characterize the hereditary non‐polyposis‐colorectal‐carcinoma syndrome
28. Dinucleotide repeat polymorphism in the human thyroid‐hormone‐receptor β gene (THRβ) on chromosome 3
29. Difference of allelotype between squamous‐cell carcinoma and adenocarcinoma of the lung
30. Six dinucleotide microsatellite polymorphisms on human chromosome 3
31. Genetic instability of microsatellite sequences in many non‐small‐cell lung carcinomas
32. p53 and chromosome‐3 abnormalities, characteristic of malignant lung tumours, are detectable in pre‐invasive lesions of the bronchus
33. Detection by the polymerase chain reaction of two polymorphisms in exon 14 of the human inter‐alpha‐trypsin‐inhibitor heavy‐chain H1 gene
34. Loss of heterozygosity at the ITIH1 locus in non‐small‐cell carcinoma of the bronchus
35. Specific chromosome defect associated with human small‐cell lung cancer: deletion 3p14‐3p23