Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system

Synapse

Volumn 21, Issue 4, 1995, Pages 289-298

  Ortiz, Jordi ^a   Fitzgerald, Lawrence W ^a   Charlton, Maura ^a   Lane, Sarah ^a   Trevisan, Louis ^a   Guitart, Xavier ^a   Shoemaker, William ^b   Duman, Ronald S ^a   Nestler, Eric J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Cocaine; Cyclic AMP dependent protein kinase; GABA receptors; Glial fibrillary acidic protein; Glutamate receptors; Morphine; Neurofilaments; Tyrosine hydroxylase

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; COCAINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TYROSINE 3 MONOOXYGENASE;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; MESOLIMBIC DOPAMINERGIC SYSTEM; NEUROFILAMENT; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; VENTRAL TEGMENTUM;

ADENYLATE CYCLASE; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE; ETHANOL; GLIAL FIBRILLARY ACIDIC PROTEIN; LIMBIC SYSTEM; MALE; NEUROFILAMENT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; RECEPTORS, GLUTAMATE; TEGMENTUM MESENCEPHALI; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 0029563776     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.890210403     Document Type: Article

References (63)

1. Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminer‐gic brain reward regions
2. Chronic morphine impairs axoplasmic transport in the mesolimbic dopamine system of the rat brain
3. Dopaminer‐gic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine‐ and cocaine‐regulated phosphoproteins
4. Neurofila‐ments and the mesolimbic dopamine system: Common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area
5. Glial fibril lary acidic protein and the mesolimbic dopamine system: Regulation by chronic morphine and Lewis‐Fischer differences in the rat ventral tegmental area
6. Sex differences in ethanol‐induced dopamine release in nucleus accum‐bens and in ethanol consumption in rats
7. A receptor subunit mRNAs: Relationship to genetiion differences in ethanol withdrawal seizure severity
8. Molecular characterization of the GABA receptor‐ approaches to molecular pharmacology
9. 9‐tetrahydrocannabinol produces naloxone‐blockable enhancement of presynaptic basal dopamine efflux in nucleus ac‐cumbens of conscious, freely‐moving rats as measured by intracere‐bral microdialysis
10. Evidence for opiate‐dopa‐mine cross‐sensitization in nucleus accumbens: Studies of conditioned reward
11. Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: Electrophysio‐logical and biochemical evidence
12. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
13. Acute and chronic ethanol exposure alters the function of hippoca mpal kainate receptors expressed in Xenopus oocytes
14. Effects of ventral striatal 6‐OHDA lesions or amphetamine sensitization on ethanol consumption in the rat
15. Regulation of cortical and subcortical glutamate receptor subunit expression by antipsychotic drugs
16. Importance of delta opioid receptors in maintaing high alcohol drinking
17. Nucleo‐side transport and ethanot induced heterologous ddesensitization
18. Ethanol withdrawal seizures and the NMDA reception complex
19. Identification of MARPP‐58, a morphine‐ and cyclic AMP‐regulated phosphoproteic 156 kD, as tyro‐sine hydroxylase: Evidence for regulation of its expression by chronic morphine in the rat locus coeruleus
20. Fischer and Lewis rat strains different basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system
21. Lewis and Fischer rat rains display differences in biochemical, electrophysiological, jfnctfeehavioral parameters: Studies in the nucleus accumbens and locus coeruleus of drug naive and morphine‐treated animals
22. Alcohol preferring (P) and non‐preferring (NP) rats display different levels of neurofilament proteins in the ventral tegmental area
23. Brain regional specificity and time‐course of changes in th NMDA receptor‐ionophore complex during ethanol withdrawa
24. Quantitative changes in al and α5 ‐γ‐aminobutyric acid type A rece tor subunit mRNAs and proteins after a single treatment of cerebel lar granule neurons with N‐methyl‐D‐aspartate
25. Electrophysiologica effects of cocaine in the mesoaccumbens dopamine system: Repeated administration
26. Alterations of GABA receptor α1‐subunit mRNA in mouse brain followingcontinu‐ous ethanol inhalation
27. Ethanol and guanine nucleotidf binding proteins: A selective interaction
28. Chronic exposure of cerebellar granules cells to ethanol results in increasec N‐methyl‐D‐aspartate receptor function
29. Drugs of abuse: anatomy, pharmacology, and function of reward pathways
30. Acute effects of ethano on GABA receptor function: Molecular and physiological determinants
31. A receptor gene expression
32. A receptor α subunits reveal that chronic alcohol treatment down‐regulates a‐subunit expression in rat brain regions
33. 2+‐ethanol interac‐tions
34. s, messenger RNA
35. A subunit mRNAs in the rat cerebral cortex
36. Drug addiction: A model for the molecular basis of neural plasticity
37. Effects of chronic ethanol consumption on G proteins in brain areas associated with the nigrostriatal and mesolimbic dopamine systems
38. Activation of protein kinase A is necessary but not sufficient for ethanol‐induced desensitization of cyclic AMP production
39. Neurobehavioral regulation of alcohol intake
40. Molecular mechanisms of drug reinforcement and addiction
41. 5‐HT and alcohol abuse
42. Acute withdrawal after repeated ethanol treatmentreduces the number of spontaneously active dopaminergic neurons in the ventral tegmental area
43. Regional, cellular, and ultra‐structural distribution of N‐methyl‐D‐aspartate receptor subunit 1 in the monkey hippocampus
44. G proteins coupled tophospholipase C: Molecular targets of long‐term ethanol exposure
45. Radioligandbinding to the N‐methyl‐D‐aspartate receptor/ionophore complex: Alterations by ethanol in vitro and by chronic in vivo ethanol ingestion
46. Time course oftyrosine hydroxylase expression after behavioral sensitization to cocaine
47. Robustness of G protein changes in cocaine sensitization shown with immunoblotting
48. Quantitative changes in G proteins do not mediate ethanol‐induced downregulation of adenylyl cyclase in mouse cerebral cortex
49. A general role for adaptations in G‐proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function
50. Chronic, ingestion of ethanol upregulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus
51. Hippocampal and cerebellar γ‐adrenergic receptors and adenylate cyclase are differentially altered by chronic ethanol ngestion
52. Amphetamine administered to the ventral tegmental area but not to the nucleus accumbens sensitizes rats to systemic morphine: Lack of conditioned effects
53. Quantitative localization of AMPA/kainate and kainate glutamate receptor subunit immunoreactivity in neurochemically identified subpopulations of neurons in the prefrontal cortex of the macaque monkey
54. Chronic cocaine administration increases CNS tyrosine hy‐droxylase enzyme activity and mRNA levels and tryptophan hydrox‐vlase enzyme activity levels
55. Chronic ethanol treatment increases expression of inhibitory G‐proteins and reduces adenylyl cyclase activity in the central nervous system of two lines of ethanol‐sensitive mice
56. Oral alcohol self‐administration stimulates dopamine release in the rat nucleus accumbens: Genetic and motivational determinants
57. Immuno‐chemical characterization of the non‐NMDA glutamate receptor using subunit‐specific antibodies: Evidence for hetero‐oligomeric structure in rat brain
58. Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system
59. The role of reward pathways in the development of drug dependence
60. Focal application of alcohol elevates extracellular dopamine in rat brain: A microdialysis study