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Volumn 7, Issue 5, 1995, Pages 340-351

Oxygen radical detoxification processes during aging:The functional importance of melatonin

Author keywords

delayed aging; free radical theory of aging; melatonin; pineal gland

Indexed keywords

ANTIOXIDANT; BACTERIUM LIPOPOLYSACCHARIDE; DNA; HYDROGEN PEROXIDE; INDOLE; MELATONIN; OXYGEN RADICAL; PARAQUAT; SAFROLE;

EID: 0029563204     PISSN: 15940667     EISSN: 17208319     Source Type: Journal    
DOI: 10.1007/BF03324344     Document Type: Review
Times cited : (90)

References (98)
  • 1
    • 77049308856 scopus 로고
    • Aging: a theory based on free radicals and radiation chemistry
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 7
    • 0003157159 scopus 로고
    • Oxidative damage by free radicals and lipid peroxidation in aging
    • B.P., Yu, CRC Press, Boca Raton
    • (1993) Free Radicals in Aging , pp. 57-88
    • Yu, B.P.1
  • 8
    • 0028606516 scopus 로고
    • Aging: prospects for further increases in the functional life span
    • (1994) Aging , vol.17 , pp. 119-146
    • Harman, D.1
  • 14
    • 0026636491 scopus 로고
    • A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson’s disease
    • (1992) Ann. Neurol. , vol.32 , pp. 128-132
    • Fahn, S.1
  • 22
    • 0026830761 scopus 로고
    • The aging pineal gland and its physiological consequences
    • (1992) BioEssays , vol.14 , pp. 169-175
    • Reiter, R.J.1
  • 25
    • 0029055175 scopus 로고
    • Oxidative processes and antioxidative defense mechanisms in the aging brain
    • (1995) FASEB J. , vol.9 , pp. 526-533
    • Reiter, R.J.1
  • 27
    • 0025758136 scopus 로고
    • Pineal melatonin: cell biology of its synthesis and of its physiological interactions
    • (1991) Endocrine Rev. , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 30
    • 0011748646 scopus 로고
    • Melatonin in the eye: functional implications
    • H.S., Yu, R.J., Reiter, CRC Press, Boca Raton
    • (1994) Melatonin , pp. 365-393
    • Yu, H.S.1
  • 31
    • 0027313442 scopus 로고
    • The contribution of extrapineal sites of melatonin synthesis to circulating melatonin levels in higher vertebrates
    • (1993) Experientia , vol.49 , pp. 665-670
    • Huether, G.1
  • 39
    • 85025890823 scopus 로고    scopus 로고
    • Wiesenberg I., Missbach M., Kahlen J.P., Schröder M., Carlberg C.: Transcriptional activation of the nuclear receptor RZRγ by the pineal hormone melatonin and identification of CGP 52608 as a synthetic ligand. Nucleic Acids Res. 23: 317–338.
  • 44
    • 0018995028 scopus 로고
    • The pineal and its hormones in the control of reproduction in mammals
    • (1980) Endocrine Rev. , vol.1 , pp. 109-131
    • Reiter, R.J.1
  • 45
    • 0029059197 scopus 로고
    • The pineal gland and melatonin in relation to aging: a summary of the theories and of the data
    • (1995) Exp. Gerontol. , vol.30 , pp. 199-212
    • Reiter, R.J.1
  • 57
    • 0023935096 scopus 로고
    • Food restriction in rodents: an evaluation of its role in the study of aging
    • (1988) J. Gerontol. , vol.43 , pp. B59
    • Masoro, E.J.1
  • 61
    • 0022602697 scopus 로고
    • The activation of tumoricidal properties in human blood monocytes by muramyl dipeptide requires specific intracellular interaction
    • (1989) J. Immunol. , vol.136 , pp. 2311-2318
    • Fogler, W.E.1    Fidler, I.J.2
  • 71
    • 0027968017 scopus 로고
    • Pineal function during aging: attenuation of the melatonin rhythm and its neurobiological consequences
    • (1994) Acta Neurobiol. Exp. , vol.54 , pp. 31-39
    • Reiter, R.J.1
  • 73
    • 84951709117 scopus 로고    scopus 로고
    • Poeggeler B., Reiter R.J., Hardeland R., Chen L.D., Tan D.X., Manchester L.C., Barlow-Walden L.R.: Melatonin and structurally-related endogenous indoles act as potent electron donors and radical scavengers in vitro. Redox Rep. (in press).
  • 78
    • 84951709118 scopus 로고    scopus 로고
    • 2-induced lipid peroxidation in homogenates of different rat brain regions. J. Pineal Res. (in press).
  • 80
    • 0027027265 scopus 로고
    • Effect of photooxidation on the eye lens and role of nutrients in delaying cataract
    • I., Emerit, B., Chance, Birkhäuser Verlag, Basel
    • (1992) Free Radicals in Aging , pp. 266-298
    • Taylor, A.1
  • 86
    • 84951709119 scopus 로고    scopus 로고
    • Sewerynek E., Melchiorri D., Chen L.D., Reiter R.J.: Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vivo. Free Rad. Biol. Med. (in press).
  • 88
    • 85025895386 scopus 로고    scopus 로고
    • Daniels W.M.U., Reiter R.J., Melchiorri D., Sewerynek E., Pablos M.I., Ortiz G.G.: Melatonin counteracts lipid peroxidation induced by carbon tetrachloride but does not restore glucose-6 phosphatase activity. J. Pineal Res. (in press).
  • 90
    • 84951709121 scopus 로고    scopus 로고
    • Pablos M.I., Agapito M.T., Gutierrez R., Recio J.M., Reiter R.J., Barlow-Walden L.R., Acuña-Castroviejo D., Menendez-Pelaez A.: Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks. J. Pineal Res. (in press).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.