Drug release from poly(dl-lactide) microspheres controlled by γ-irradiation

Journal of Controlled Release

Volumn 37, Issue 3, 1995, Pages 263-267

  Yoshioka, S ^a   Aso, Y ^a   Kojima, S ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Controlled release; Glass transition temperature; Poly(dl lactide) microsphere; Polymer decomposition; Irradiation

Indexed keywords

GLASS; MICROSPHERE; POLYLACTIDE; POLYMER; PROGESTERONE;

ARTICLE; CONTROLLED STUDY; DRUG RELEASE; GAMMA IRRADIATION; MOLECULAR WEIGHT; PHASE TRANSITION; PRIORITY JOURNAL; RADIATION DOSE; TEMPERATURE;

EID: 0029561636     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00083-6     Document Type: Article

References (10)

1. Effects of storage on the physicochemical properties and release characteristics of progesterone-loaded poly(l-lactide) microspheres
2. Effect of temperature on mechanisms of drug release and matrix degradation of poly(dl-lactide) microspheres
3. Effects of storage on the physicochemical properties and release characteristics of progesterone-loaded poly(l-lactide) microspheres
4. Gamma sterilization of a semi-solid poly(ortho ester) designed for controlled drug delivery-validation and radiation effects
5. Gamma irradiation of carboxymethylcellulose: technological and pharmaceutical aspects
6. The effect of gamma radiation on the tableting properties of some pharmaceutical excipients
7. Influence of average molecular weights of poly(dl-lactic acid-co-glycolic acid) copolymers 50/50 on phase separation and in vitro drug release from microspheres
8. The influence of terminal gamma-sterilization on captopril containing poly(dl-lactide-co-glycolide) microspheres
9. The effect of γ-irradiation on drug release from poly(lactide) microspheres
10. New method for analysis of biodegradable polyesters by high-performance liquid chromatography after alkali hydrolysis