Prediction of solvent removal profile and effect on properties for peptide-loaded PLGA microspheres prepared by solvent extraction/ evaporation method

Journal of Controlled Release

Volumn 37, Issue 3, 1995, Pages 199-214

  Li, Wen I ^a   Anderson, Kimberly W ^b   Mehta, Rahul C ^c   Deluca, Patrick P ^c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c University of Kentucky   (United States)

Author keywords

Controlled release; Microsphere; Pore formation; Solvent removal

Indexed keywords

DICHLOROMETHANE; MICROSPHERE; POLYGLACTIN; POLYMER; SALCATONIN; SOLVENT;

ARTICLE; CONTROLLED STUDY; DISPERSION; EVAPORATION; MATHEMATICAL MODEL; PHASE TRANSITION; PREDICTION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TECHNIQUE; TEMPERATURE; THEORY;

EID: 0029561449     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00076-3     Document Type: Article

References (11)

1. Preformed porous microspheres for controlled and pulsed release of macromolecules
2. Effect of solvent removal technique on the matrix characteristics of peptide-loaded PLGA microsphere
3. Kinetic and thermodynamic modeling of the formation of polymeric microspheres using solvent extraction/ evaporation method
4. Diffusion-Controlled formation of porous structures in ternary systems
5. The investigation of solution thermodynamics for the polysulfone-DMAC-water system
6. Analysis of the structure determining process of phase inversion membranes
7. Rheology of microsphere formation and refinement
8. Biodegradable cisplatiim microspheres prepared by the solvent evaporation method: Morphology and release characteristics
9. Biodegradable microsphere as depot system for parenteral delivery of peptide drugs
10. Correlation of matrix properties and initial release behavior of calcitonin PLGA-microspheres