Acute phase protein concentrations predict parasite clearance rate during therapy for visceral leishmaniasis

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 89, Issue 6, 1995, Pages 678-681

  Wasunnal, K M ^a   Raynes, J G ^b   Werel, J B O ^a   Muigai, R ^c   Sherwood, J ^a,d   Gachihi, G ^a   Carpenter, L ^b   Mc Adam, K P W J ^b  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c NOVARTIS PHARMA AG   (Switzerland)

^d Walter Reed Project   (Kenya)

Author keywords

Acute phase proteins; C reactive protein; Leiskmania donovani; Serum amyloid A protein; Visceral leishmaniasis

Indexed keywords

ACUTE PHASE PROTEIN; ANTIFUNGAL AGENT; ANTIPROTOZOAL AGENT; C REACTIVE PROTEIN; KETOCONAZOLE; MARKER; OROSOMUCOID; SERUM AMYLOID A; STIBOGLUCONATE SODIUM;

ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KENYA; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; VISCERAL LEISHMANIASIS;

ACUTE-PHASE PROTEINS; ANIMALS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; FOLLOW-UP STUDIES; HUMANS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; OROSOMUCOID; SENSITIVITY AND SPECIFICITY; SERUM AMYLOID A PROTEIN; SPLEEN;

LEISHMANIA DONOVANI;

EID: 0029559976     PISSN: 00359203     EISSN: 18783503     Source Type: Journal    
DOI: 10.1016/0035-9203(95)90442-5     Document Type: Article

References (26)

1. Abemethy, T. J. & Avery, O. T. (1941). The occurrence during acute infections of a protein not normally present in blood. 1. Distribution of the reactive protein in patient’s sera and the effect of calcium on the flocculation reaction with C polysaccharide of pneumococcus. Journal of Experimental Medicine, 73, 173-182.
2. Adhikari, M., Coovadia, H. M., Coovadia, V. M., Smit, S. Y. & Moosa, A. (1986). Predictive value of C-reactive protein in neonatal septicaemia. Annals of Tropical Paediatrics, 6, 37-40.
3. Ballou, S. P. & Macintyre, S. S. (1990). The absence of a binding reactivity of human C-reactive protein for immunoglobulin or immune complexes. Journal of Laboratory and Clinical Medicine, 115, 332-338.
4. Cennini, P., Berhe, N., Hailu, A., McGinnes, K. & Frommel, D. (1993). Mononuclear cell subpopulations and cytokine level in human visceral leishmaniasis before and after chemotherapy. Journal of Infectious Diseases, 168, 986-993.
5. Chakrabarti, A., Maire, M., Saha, K. & Lambert, P. H. (1983). Identification of components of immune complexes purified from human sera. II. Demonstration of mycobacterial antigens in immune complexes isolated from sera of leprosy patients. Clinical and Experimental Immunology. 51, 225—231.
6. Chandra, I., Acharyulu, G. S., Kannapiran, M., Segaran, R. & Sarma, R. G. (1990). Acute phase proteins in tuberculosis patients. Indian Journal of Chest Disease and Allergy Science, 32, 15-23.
7. Chulay, J. D. & Bryceson, A. D. M. (1983). Quantitation of amastigotes of Leishmania donovani in smears of splenic aspirates from patients with visceral leishmaniasis. American Journal of Tropical Medicine and Hygiene, 32, 475-479.
8. Fey, G. H. & Fuller, G. M. (1987). Regulation of acute phase gene expression by inflammatory mediators. Molecular Biology and Medicine, 4, 323-338.
9. Ghalib, H. W., Piuvezam, M. R., Skeiky, Y. A., Siddig, M., Hashim, F. A., el Hassan, A. M., Russo, D. M. & Reed, S. G. (1993). Interleukin 10 correlated with pathology in human Leishmania donovani infections. Journal of Clinical Investigation, 92, 324-329.
10. Gillespie, S. H., Dow, C., Raynes, J. G., Behrens, R. H., Chiodini, P. L. & McAdam, K. P. W. J. (1991). Measurement of acute phase proteins for assessing severity of Plasmodium falciparum malaria. Journal of Clinical Pathology, 44, 228-231.
11. Grange, J. M., Kardjito, T. & Setiabudi, I. (1984). A study of acute-phase reactant proteins in Indonesian patients with pulmonary tuberculosis. Tubercle, 65, 23-39.
12. Kannapiran, M., Chandra, I., Krishnamurthy, P. V. & Raghu- pati, S. G. (1989). C-reactive protein levels in patients with pulmonary tuberculosis. Lung India, 7, 34-36.
13. Koj, A. (1974). Acute-phase reactants. Their synthesis, turnover and biological significance. In: Structure and Function of Plasma Proteins, vol. 1, Allison, A. (editor). New York: Plenum Press, pp. 72-131.
14. Laurent, P. E. (1989). Clinical measurement of acute phase proteins to detect and monitor infectious diseases. In: Acute Phase Proteins in the Acute Phase Response, Pepys, M. B. (editor). London: Springer, pp. 151-160.
15. Lightner, L. K., Chulay, J. D. & Bryceson, A. D. M. (1983). Comparison of microscopy and culture in the detection of Leishmania donovani from splenic aspirates. American Journal of Tropical Medicine and Hygiene, 32, 296229.
16. McAdam, K. P. W. J. (1978). Leprosy, filariasis and malaria as a cause of secondary amyloidosis. Papua New Guinea Medical Journal, 21, 69-78.
17. Mebrahtu, Y., Lawyer, P., Githure, J., Were, J. B., Muigai, R., Hendricks, L., Leeuwenburg, J., Koech, D. & Roberts, C. (1989). Visceral leishmaniasis unresponsive to pentostam caused by Leishmania donovani in Kenya. American Journal of Tropical Medicine and Hygiene, 41, 289-294.
18. Murray, H. W., Rubin, B. Y. & Rothermel, C. D. (1983). Killing of intracellular Leishmania donovani by lymphokine- stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine. Journal of Clinical Investigation, 72, 1506-1510.
19. Naik, P. & Voller, A. (1984). Serum C-reactive protein levels and falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 78, 812-813.
20. Pepys, M. B. & Baltz, M. L. (1983). Acute phase proteins with special reference to C-reactive protein and related protein (pentaxins) and serum amyloid A protein. Advances in Immunology, 34, 141-212.
21. Raynes, J. G., Curry, A. J. & Harris, R. (1993). Binding of CRP to Leishmania species. Biochemical Society Transactions, 22, 35.
22. Squires, K. E., Rosenkaimer, F., Sherwood, J. A., Forni, A. L., Were, J. B. O. & Murray, H. W. (1993). Immunoche- motherapy for visceral leishmaniasis: A controlled pilot trial of antimony versus antimony plus gamma interferon. American Journal of Tropical Medicine and Hygiene, 48, 666-669.
23. Tillet, W. S. & Francis, T. (1930). Serological reactions in pneumonia with a non-protein somatic fraction of penumo- coccus. Journal of Experimental Medicine, 52, 561-567.
24. Thompson, R. A., Sukumaran, K. D. & Rajagopalan, K. (1985). Inappropriate responses to Mycobacterium leprae infection — C-reactive protein in man and serum amyloid P in mice. Clinical and Experimental Immunology, 61, 329-335.
25. Vigushin, D. M., Pepys, M. B. & Hawkins, P. N. (1993). Metabolic and scintigraphic studies of radioiodinated human CRP in health and disease. Journal of Clinical Investigation, 91, 1351-1357.
26. WHO (1984). The Leishmaniases. Report of a WHO Expert Committee. Geneva: World Health Organization, Technical Report Series, no. 701.