Mouse T-cell receptor variable gene segment families

Immunogenetics

Volumn 42, Issue 6, 1995, Pages 501-530

  Arden, Bernhard ^a   Clark, Stephen P ^b   Kabelitz, Dieter ^a   Mak, Tak W ^c  

^a PAUL EHRLICH INSTITUT   (Germany)

^b AMGEN INC   (United States)

^c AMGEN INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE STRUCTURE; GENETIC VARIABILITY; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE RECEPTOR GENE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; MICE; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SEQUENCE ALIGNMENT; TERMINOLOGY;

EID: 0029559690     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/BF00172177     Document Type: Review

References (118)

1. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention
2. Diversity and structure of genes of the α family of mouse T-cell antigen receptor
3. Human T-cell receptor variable gene segment families
4. Limited diversity of γδ antigen receptor genes of Thy-1+ dendritic epidermal cells
5. βThe murine T-cell receptor uses a limited repertoire of expressed gene segments
6. Variability and repertoire size of T-cell receptor Vα gene segments
7. T-cell receptor β-chain expression: dependence on relatively few variable region genes
8. Alternative splicing of murine T-cell receptor β-chain transcripts
9. Murine T-cell receptor mutants with deletions of β-chain variable region genes
10. Structure and specificity of T cell receptor γδ on major histocompatibility complex antigen-specific CD3+, CD4−, CD8− T lymphocytes
11. Vβ17 gene polymorphism in wild-derived mouse strains: two amino acid substitutions in the Vβ17 region greatly alter T cell receptor specificity
12. A third type of murine T-cell receptor gene
13. Somatic recombination in a murine T-cell receptor gene
14. T-cell receptor δ gene rearrangements in early thymocytes
15. A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation
16. The outline structure of the T-cell αβ receptor
17. T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments
18. Tandem linkage and unusual RNA splicing of the T-cell receptor β-chain variable-region genes
19. MALIGNED: a multiple sequence alignment editor
20. Comparison of human and mouse T-cell receptor variable gene segment subfamilies
21. Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed α⊙ dimer
22. Transfer of specificity by murine α and β T-cell receptor genes
23. A comprehensive set of sequence analysis programs for the VAX
24. The adult T-cell receptor δ-chain is diverse and distinct from that of fetal thymocytes
25. Change in antigen specificity of cytotoxic T-lymphocytes is associated with the rearrangement and expression of a T-cell receptor β-chain gene
26. Correlations between T-cell specificity and the structure of the antigen receptor
27. α T cell receptor secondary rearrangements in a murine T cell lymphoma
28. α segments correlates with ongoing T-cell receptor α-chain rearrangement
29. Post-transcriptional allelic exclusion of two functionally rearranged T cell receptor α genes
30. Diversity, rearrangement, and expression of murine T cell gamma genes
31. Expression of T cell receptor genes in an antigen-specific hybridoma and radiation-induced variants
32. A T-cell receptor γδ-specific monoclonal antibody detects a Vγ5 region polymorphism
33. β and MHC restriction
34. Non-germ-line elements (NGE) are present in the T cell receptor β-chain genes isolated from the mutant mouse, motheaten (me/me)
35. Limited receptor repertoire in a mycobacteria-reactive subset of γδ T lymphocytes
36. Thymocyte development: an analysis of T cell receptor gene expression in 519 newborn thymocyte hybridomas
37. Unusual organization and diversity of T-cell receptor α-chain genes
38. Structure, organization, and somatic rearrangement of T cell gamma genes
39. Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins
40. Selection of amino acid sequences in the beta chain of the T cell antigen receptor
41. Diversity of murine gamma genes and expression in fetal and adult T lymphocytes
42. T cell receptor α and β gene expression in a murine antigen-specific T suppressor lymphocyte clone with cytolytic potential
43. Conserved V(D)J junctional sequence of crossreactive cytotoxic T-cell receptor idiotype and the effect of a single amino acid substitution
44. b/TNP responce
45. A novel type of aberrant T cell receptor α-chain gene rearrangement: implications for allelic exclusion and the V-J recombination process
46. T cell-specific γ genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes
47. T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones
48. Novel excision products of T cell receptor γ gene rearrangements and developmental stage specificity implied by the frequency of nucleotide insertions at signal joints
49. δ) region
50. The T cell receptor Vα11 gene family: analysis of allelic sequence polymorphism and demonstration of Jα region-dependent recognition by allele-specific antibodies
51. k-restricted T helper hybridomas
52. Allelic differences in TCR γ-chains alter γδ T cell antigen reactivity
53. A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product
54. Functional α and β T cell chain receptor messages can be detected in old but not in young athymic mice
55. Restriction fragment length polymorphisms of the mouse T-cell receptor gene families [published erratum appears in Immunogenetics 30: 235, 1989]
56. Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor Cα/Cδ region
57. Predominant variable region gene usage by γ/δ T cell receptor-bearing cells in the adult thymus
58. Rearrangement by inversion of a T-cell receptor δ variable region gene located 3' of the δ constant region gene
59. Predominant use of a particular α-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin
60. Sequence of the TCR β chain gene used by a T cell clone specific for the synthetic polymer, GAT
61. Limited diversity of the rearranged T-cell γ gene
62. T cell receptor gene usage in the response to λ repressor cI protein: an apparent bias in the usage of a Vα gene element
63. Physical maps of the mouse and human immunoglobulin-like loci
64. T cell receptor β-chain genes in BW5147 and other AKR tumors: deletion order of murine Vβ gene segments and possible 5' regulatory regions
65. Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α-mRNA of BW5147 origin
66. β) genes
67. Rules and guidelines for gene nomenclature
68. Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements
69. A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition
70. The joining of germ-line Vα to Jα genes replaces the preexisting Vα-Jα complexes in a T cell receptor α,β positive T cell line
71. δ-chains of dendritic epidermal T cell receptors are diverse but pair with γ-chains in a restricted manner
72. Two distinct mechanisms account for the immune response (Ir) gene control of the T cell response to pigeon cytochrome c
73. β13Sequence of the gene used by an influenza-specific T cell
74. A mouse T lymphoma that lacks T-cell receptor surface expression exhibits allelic exclusion of its β chain genes
75. Isolation of cDNA clones encoding a T-cell receptor β-chain from a beef insulin-specific hybridoma
76. Thymocyte circular DNA excised from T cell receptor α-δ gene complex
77. The T-cell receptor from an influenza-A specific murine CTL clone
78. Structure, expression and divergence of T-cell receptor β-chain variable regions
79. γ gene that shows remarkable evolutionary conservation
80. α family
81. Surprisingly uneven distribution of the T cell receptor Vβ repertoire in wild mice
82. The structure, function, and molecular genetics of the γ/δ T cell receptor
83. A highly homologous T-cell receptor β-chain variable region is expressed in mouse and human T cells
84. Polymorphism of the Tcrg-V1-V2 region in mice: identification of a new Vg1 allele in DBA/2
85. Coding sequence polymorphism of Tcrg-V1, -V2, and -V4 genes in mice bearing Tcr-gA and -gC haplotypes
86. βIdentical T-cell receptor genes used in alloreactive cytotoxic and antigen plus I-A specific helper T cells
87. No functional γ-chain transcripts detected in an alloreactive cytotoxic T-cell clone
88. T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes
89. A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes
90. Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences
91. Organization, sequence, and function of 34.5 kb of genomic DNA encompassing several murine T-cell receptor α/δ variable gene segments
92. Molecular analysis of antigen recognition by insulin-specific T-cell hybridomas from B6 wild-type and bm 12 mutant mice
93. Clonal diversity and T-cell receptor β-chain variable gene expression in enlarged lymph nodes of MRL- lpr/lpr lupus mice
94. Identification of a T cell receptor β chain variable region, Vβ20, that is differentially expressed in various strains of mice
95. Coding sequence polymorphisms among Vβ T cell receptor genes
96. b) mice
97. The EMBL Network File Server
98. The EMBL data library
99. A new mouse T-cell receptor α chain variable region family
100. T cell receptor-γ and −δ genes preferentially utilized by adult thymocytes for the surface expression
101. Excision products of the T cell receptor gene support a progressive rearrangement model of the α/δ locus
102. The T cell receptor Vα3 gene segment is associated with reactivity to p-azobenzenearsonate
103. Structure-function relationships among highly diverse T cells that recognize a determinant from influenza virus hemagglutinin
104. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
105. Structure of extrachromosomal circular DNAs excised from T-cell antigen receptor alpha- and delta-chain loci
106. Normal T cell development is possible without “functional” γ chain genes
107. In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes
108. Preferential association of α and β chains of the T cell antigen receptor
109. Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy
110. A new method for predicting signal sequence cleavage sites
111. Molecular basis for the nonexpression of Vβ17 in some strains of mice
112. Nomenclature for T-cell receptor (TCR) gene segments of the immune system
113. Genomic organization of the genes encoding mouse T-cell receptor α-chain
114. αPredominant use of a gene segment in mouse T-cell receptors for cytochrome c
115. The structure of Vα and Jα segments in the mouse
116. Restricted V-segment usage in T-cell receptors from cytotoxic T Lymphocytes specific for a major epitope of lymphocytic choriomeningitis virus
117. Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages