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Volumn 275, Issue 3, 1995, Pages 1476-1483
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Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells
a
a
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Author keywords
[No Author keywords available]
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Indexed keywords
CLOZAPINE;
DRUG METABOLITE;
GLUTATHIONE;
HYPOCHLOROUS ACID;
MYELOPEROXIDASE;
NITRENIUM ION;
UNCLASSIFIED DRUG;
AGRANULOCYTOSIS;
ARTICLE;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
COVALENT BOND;
DOSE TIME EFFECT RELATION;
DRUG ACTIVATION;
DRUG CYTOTOXICITY;
DRUG OXIDATION;
HUMAN;
HUMAN CELL;
LEUKOCYTE ACTIVATION;
NEUTROPHIL;
NORMAL HUMAN;
NUCLEAR MAGNETIC RESONANCE;
PRIORITY JOURNAL;
ANTIPSYCHOTIC AGENTS;
BINDING SITES;
CLOZAPINE;
FREE RADICALS;
GLUTATHIONE;
HUMANS;
HYPOCHLOROUS ACID;
NEUTROPHIL ACTIVATION;
NEUTROPHILS;
OXIDATION-REDUCTION;
PEROXIDASE;
REFERENCE VALUES;
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EID: 0029555342
PISSN: 00223565
EISSN: None
Source Type: Journal
DOI: None Document Type: Article |
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Times cited : (185)
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References (0)
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