Potential DNA Vaccine Integration into Host Cell Genome

Annals of the New York Academy of Sciences

Volumn 772, Issue 1, 1995, Pages 30-39

  NICHOLS, WARREN W ^a   LEDWITH, BRIAN J ^a   MANAM, SUJATA V ^a   TROILO, PHILIP J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; DNA VACCINE; PLASMID DNA; VACCINE;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTAMINATION; CONTROLLED STUDY; DNA PURIFICATION; GEL ELECTROPHORESIS; GENE ACTIVATION; GENE FREQUENCY; GENE MUTATION; GENOME; HOST CELL; INTEGRATION; INTRAMUSCULAR DRUG ADMINISTRATION; MOUSE; MUTAGENESIS; NONHUMAN; ONCOGENE; PLASMID; POLYMERASE CHAIN REACTION; QUADRICEPS FEMORIS MUSCLE; RISK ASSESSMENT; TECHNIQUE; TUMOR SUPPRESSOR GENE;

EID: 0029552275     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1995.tb44729.x     Document Type: Article

References (8)

1. The length of homology required for gene targeting in embryonic stem cell
2. Targeted mutation of the Hprt gene in mouse embryonic stem cells
3. Overview of biological effects of addition of DNA molecules to cells
4. Long‐term persistence of plasmid DNA and foreign gene expression in mouse muscle
5. Regulatory considerations for nuclei acid vaccines
6. Safety considerations for nucleic acid vaccines
7. Two‐stage ligation‐mediated PCR enhances the detection of integrated transgenic DNA
8. Novel use of polymerase chain reaction to amplify cellular DNA adjacent to an integrated provirus