Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro

Journal of Pharmacology and Experimental Therapeutics

Volumn 275, Issue 3, 1995, Pages 1131-1135

  Ring, B J ^a   Binkley, S N ^a   Roskos, L ^a   Wrighton, S A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HYDROXYMIDAZOLAM; CYTOCHROME P450; DRUG DERIVATIVE; DRUG METABOLITE; FLUNITRAZEPAM; FLUOXETINE; NORFLUOXETINE; NORSERTRALINE; SERTRALINE;

ARTICLE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG MIXTURE; ENZYME MECHANISM; HUMAN; HUMAN TISSUE; LIVER; PRIORITY JOURNAL; PROTEIN FAMILY;

1-NAPHTHYLAMINE; CATALYSIS; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; FLUOXETINE; HUMANS; MICROSOMES, LIVER; MIDAZOLAM; MIXED FUNCTION OXYGENASES; SEROTONIN UPTAKE INHIBITORS; SERTRALINE;

EID: 0029549892     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)