Comparative modeling of the three cp modules of the ß-chain of c4bp and evaluation of potential sites of interaction with protein s

Protein Engineering, Design and Selection

Volumn 8, Issue 12, 1995, Pages 1253-1258

  Villoutreix, Bruno O ^a,b   Ferndndez, Jose A ^a   Teleman, Olle ^a   Griffin, John H ^a  

^a VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

C4b binding protein; Electrostatics; Protein modeling; Protein S

Indexed keywords

BINDING PROTEIN; COMPLEMENT COMPONENT C4B; COMPLEMENT COMPONENT C4B BINDING PROTEIN; MUTANT PROTEIN; PROTEIN S; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPUTER MODEL; CONTROLLED STUDY; GENETIC PROCEDURES; HYDROPHOBICITY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BINDING SITES; COMPLEMENT FACTOR H; COMPLEMENT INACTIVATOR PROTEINS; COMPUTER GRAPHICS; COMPUTER SIMULATION; CONSENSUS SEQUENCE; GLYCOPROTEINS; GLYCOSYLATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN BINDING; PROTEIN S; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, COMPLEMENT;

EID: 0029549192     PISSN: 17410126     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/8.12.1253     Document Type: Article

References (25)

1. Barlow, P.N., Norman, D.G., Steinkasscrer, A., Home, T.J., Pearce, J., Driscoll, P.C., Sim, R.B. and Campbell, I.D. (1992) Biochemistry, 31, 36263634.
2. Barlow, P.N., Steinkasscrer, A., Norman, D.G., Kieffer, B., Wiles, A.P., Sim, R.B. and Campbell, I.D. (1993) J. Mol Biol., 232, 268-284.
3. Bowie, J.U., Ltlthy, R. and Eisenberg, D. (1991) Science, 253, 164-170.
4. Dahlbäck, B. (1983) Biochem. J" 209, 847-856
5. Dahlbäck, B. (1986) J. Biol. Chem., 261, 12022-12027.
6. Femdádez, J.A. and Griffln, J.H. (1994) J. Biol. Chem., 269, 2535-2540.
7. Femdádez, J.A., Heeb, M.J. and Griffln, J.H. (1993) J. Biol. Chem., 268, 16788-16794.
8. Femdádez, J.A., Villouireix, B.O., Hackeng, T.M., Griffln, J.H. and Boujna, B.N., (1994) Biochemistry, 33, 11073-11078.
9. Garcia de Frutos, P. and Dahlblick, B. (1995) Biochim. Biophys. Acta, 1261, 285-289.
10. Gilson, M., Sharp, K. and Honig, B. (1987) J. Comput. Chem., 9, 327-335.
11. Greer J. (1985) Science, 228, 1055-1060.
12. Griffln, J.H., Gmber, A. and Femdádez, J.A. (1992) Blood, 79, 3203-3211.
13. Hardig, Y., Rezaie, A. and Dahlbiick, B. (1993) J. Biol. Chem., 268, 3033-3036.
14. Hessing, M., Kanters, D., Takeya, H., van’t Veer, C., Hackeng, T.M., Iwanaga, S. and Bouma, B.N. (1993) FEBS Lett., 259, 53-56.
15. Hillarp, A. and Dahlbfick, B. (1988) J. Biol. Chem., 263, 12759-12764.
16. Hillarp, A. and Dahlback, B. (1990) Proc. Natl Acad. Sci. USA, 81, 1183-1187.
17. Hillarp, A., Hessing, M. and Dahlbfick, B. (1989) FEBS Lett., 259, 53-56.
18. Klapper, I., Hagstrom, R., Fine, R., Sharp, K. and Honig, B. (1986) Proteins, 1, 47-59.
19. Mackay, D., Cross, A.J. and Hagler, A.T. (1990) In Fasman, G.D. (ed.). Prediction of Protein Structure and the Principles of Protein Conformation. Plenum Press, New York, pp. 317-358.
20. Mesters, R.M., Houghten, R.A. and Griffln, J.H. (1991) J. Biol. Chem., 266, 24514-24519.
21. Norman, D.G., Barlow, P.N., Baron, M., Day, A.J., Sim, R.B. and Campbell, I.D. (1991) J. Mol. Biol., 219, 717-725.
22. Ogata, R.T., Mathias, P., Bradt, B.M. and Cooper, N.R. (1993) J. Immunol., 150, 2273-2280.
23. Rashin, A.A. and Honig, B. (1984) J. Mol. Biol., 173, 515-521.
24. Scharfstein, J., Ferreira, A., Gigli, I. and Nussenzweig, V. (1978) J. Exp. Med., 148, 207-222.
25. Villoutreix, B.O., Getzoff, E.D. and Griffin, J.H. (1994) Protein Sci., 3, 2033-2044.