Placental and fetal hepatic growth are selectively inhibited by prolonged reductions of uterine blood flow in pregnant sheep

Reproduction, Fertility and Development

Volumn 7, Issue 3, 1995, Pages 405-410

  McLellan, Kenneth C ^a   Bocking, Alan D ^a   White, Susan E ^a   Han, Victor K M ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; BODY WEIGHT; FEMALE; FETUS; GESTATIONAL AGE; GROWTH, DEVELOPMENT AND AGING; LIVER; METABOLISM; PLACENTA; PREGNANCY; PRENATAL DEVELOPMENT; SHEEP; UTERUS; VASCULARIZATION;

ANIMALS; BODY WEIGHT; DNA; FEMALE; FETUS; GESTATIONAL AGE; LIVER; PLACENTA; PREGNANCY; PROTEINS; SHEEP; UTERUS;

EID: 0029443451     PISSN: 10313613     EISSN: 14485990     Source Type: Journal    
DOI: 10.1071/RD9950405     Document Type: Article

References (12)

1. Bristow, J., Rudolph, A. M., Itskovitz, J., and Barnes, R. (1983). Hepatic oxygen and glucose metabolism in the fetal lamb. J. Clin. Invest. 71, 1047-61.
2. Clapp, J. F. hi, McLaughlin, M. K., Larrow, R., Famham, J., and Mann, L. I. (1982). The uterine hemodynamic response to repetitive unilateral vascular embolization in the pregnant ewe. Am. J. Obstet. Gynecol. 114, 309-18.
3. Creasy, R. K., Barrett, C. T., De Swiet, M., Kahanpaa, K. V., and Rudolph, A. M. (1972). Experimental intrauterine growth retardation in the sheep. Am. J. Obstet. Gynecol. 112, 566-73.
4. Edelstone, D. I., Rudolph, A. M., and Heymann, M. A. (1978). Liver and ductus venosus blood flow in fetal lambs in utero. Circ. Res. 42, 426-33.
5. Edelstone, D. I., Rudolph, A. M., and Heymann, M. A. (1980). Effects of hypoxemia and decreasing umbilical flow on liver and ductus venosus blood flows in fetal lambs. Am. J. Physiol. 238, H656-H663.
6. Fuller, E. O., Galletti, P. M., and Takeuchi, T. (1975). Major and collateral components of blood flow to pregnant sheep uterus. Am I Phvsinl. 229. 279-85.
7. Han, V. K. M., Hill, D. J., Strain, A. J., Towle, A. C., Lauder, J. M., Underwood, L. E., and D’Ercole, A. J. (1987). Identification of somatomedin/insulin-like growth factor immunoreactive cells in the human fetus. Pediatr. Res. 22, 245-9.
8. Hooper, S. B., Bocking, A. D., White, S., Challis, J. R. G., and Han, V. K. M. (1991). DNA synthesis is reduced in selected fetal tissues during prolonged hypoxemia. Am. J. Physiol. 261, R508-R514.
9. Lunell, N. O., Sarby, B., Lewander, R., and Nylund, L. (1979). Comparison of uteroplacental blood flow in normal and in intrauterine growth-retarded pregnancy. Gynecol. Obstet. Invest. 10, 106-18.
10. Reuss, M. L., and Rudolph, A. M. (1980). Distribution and recirculation of umbilical and systemic venous blood flow in fetal lambs during hypoxia. J. Dev. Physiol. 2, 71-84.
11. Rosenfeld, C. R., Morriss, F. H. Jr, MakowsRi, E. L., Meschia, G., and Battaglia, F. C. (1974). Circulatory changes in the reproductive tissues of ewes during pregnancy. Gynaecol. Invest. 5, 252-68.
12. Vatnick, I., and Bell, A. W. (1992). Ontogeny of fetal hepatic and placental growth and metabolism in sheep. Am. J. Physiol. 263, R619-R623.