Age-related changes in IGFBP-4 and IGFBP-5 levels in human serum and bone: Implications for bone loss with aging

Progress in Growth Factor Research

Volumn 6, Issue 2-4, 1995, Pages 465-473

  Mohan, S ^a   Farley, J R ^a   Baylink, D J ^a  

^a LOMA LINDA UNIVERSITY   (United States)

Author keywords

aging; Bone cells; bone formation; osteoporosis

Indexed keywords

SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C;

AGING; BONE; BONE DEVELOPMENT; HUMAN; METABOLISM; OSTEOLYSIS; OSTEOPOROSIS; REVIEW;

AGING; BONE AND BONES; BONE RESORPTION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; OSTEOGENESIS; OSTEOPOROSIS;

EID: 0029433441     PISSN: 09552235     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-2235(95)00027-5     Document Type: Article

References (27)

1. Consensus development conference: prophylaxis and treatment of osteoporosis
2. Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota 1986–1989
3. How many women have osteoporosis?
4. The role of insulin-like growth factor-II in the coupling of bone formation to resorption
5. Quantitative histological studies on the pathogenesis of uremic bone disease
6. Bone growth factors
7. Growth factors to stimulate bone formation
8. Growth factors and the regulation of bone remodelling
9. Skeletal size increases during tanner stages II & III: Association with a marked upregulation of the serum IGF system
10. Growth hormone (GH) treatment increases serum levels of IGF-I, IGF-II, IGFBP-3 and IGFBP-5 in children with GH deficiency
11. Regulation and actions of insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 in bone: physiological and clinical implications
12. Insulin-like growth factor binding proteins in bone cell regulation
13. Studies on the molecular mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells
14. Development of a simple, valid method for the complete removal of insulin-like growth factor binding proteins from IGFs in human serum and other biological fluids: comparison with acid-ethanol extraction and C-18 Sep-Pak Separation
15. Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids
16. Recombinant synthesis of insulin-like growth factor binding protein (IGFBP)-4 and its application in the development of an RIA: evidence for regulation of IGFBP-4 production in vitro and in vivo by PTH
17. Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa
18. Clinical Studies of IGFBP-2 by radioimmunoassay
19. Radioimmunoassay of insulin-like growth factor binding protein-6 in human serum and other biological fluids
20. A specific radioimmunoassay for the growth hormone (GH)-dependent somatomedin-binding protein: its use for diagnosis of GH deficiency
21. Insulin-like growth factors I and II peptide messenger ribonucleic acid and gene structures, serum and tissue concentrations
22. Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)
23. Age-related decreases in insulin-like growth factor-I and transforming growth factor β in femoral cortical bone from both men and women: implications for bone loss with aging
24. An age-related decrease of insulin-like growth factor binding protein-5 in human cortical bone
25. Program: Seventeenth annual meeting of The American Society for Bone and Mineral Research
26. Structural and functional analysis of the human insulin-like growth factor binding protein-5 promoter: demonstration of a functional progesterone response element(s)
27. The magnitude of the production of insulin-like growth factor system components is skeletal site dependent