TGF-β and megakaryocytes in the pathogenesis of myelofibrosis in myeloproliferative disorders

Leukemia and Lymphoma

Volumn 20, Issue 1-2, 1995, Pages 39-44

  Martyré, Marie Claire ^a  

^a INSTITUT CURIE   (France)

Author keywords

Megakaryocytes; Myelofibrosis; Myeloproliferative disorders; TGF

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

BONE MARROW CELL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; MEGAKARYOCYTE; MYELOFIBROSIS; MYELOID METAPLASIA; MYELOPOIESIS; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL; REVIEW; THROMBOCYTE;

CELL DIVISION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MEGAKARYOCYTES; MYELOFIBROSIS; MYELOPROLIFERATIVE DISORDERS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029417041     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199509054751     Document Type: Article

References (58)

1. Zwi Fälle von Leukämie mit eigenthümlichem blut-resp. Knochenmarksbefund
2. Myelofibrosis in chronic myeloproliferative disorders. Incidence among subtypes according to the Hannover classification
3. Some speculations on the myeloproliferative syndromes
4. The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with myeloproliferative syndrome
5. Life expectancy of patients with chronic nonleukemic myeloproliferative disorders
6. A G-6-PD variant with heterozigous expression in blood cells of a woman with primary myelofibrosis
7. Agnogenic myeloid metaplasia: a clonal proliferation of hematopoietic stem cells with secondary myelofibrosis
8. Characteristics of bone marrow fibroblast colony forming cells and their progeny in patients with myeloproliferative disorders
9. Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: clonal analysis of a case characterised by a N-ras gene mutation
10. Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia
11. Clonal granulocytes and bone marrow cells in the cellular phase of agnogenic myeloid metaplasia
12. Myeloid progenitor cells in the circulation of patients with myelofibrosis and other myeloproliferative disorders
13. Allogenic bone marrow transplantation for primary myelofibrosis
14. Bone marrow biopsy in haematological disorders
15. Megakaryoblastic transformation of myelofibrosis with expression of the c-sis oncogene
16. Déficit congénital en alpha granules plaquettaires et fibrose réticulinique médullaire. Hypothèse physiopathogénique
17. Human megakaryocyte stimulation of proliferation of bone marrow fibroblasts
18. Pathogenesis of myelofibrosis: role of ineffective megakaryopoiesis and megakaryocyte components
19. Platelet function in myeloproliferative disorders: characterisation and sequential studies show multiple platelet abnormalities, and change with time
20. Platelet PDGF and TGF-β levels in myeloproliferative disorders
21. Transforming growth factor-β regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts
22. Effects of platelet derived growth factor, epidermal growth factor and transforming growth factor-β on the growth of human marrow fibroblasts
23. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells
24. The cell biology of transforming growth factor beta
25. The transforming growth factor-betas
26. Latent high molecular weight complex of transforming growth factor-β1
27. Synthesis of transforming growth factor-β1 by megakaryocytes and its localisation to megakaryocytes and α-granules
28. Idiopathic myelofibrosis
29. Immunohistochemical study of basement membrane proteins and type III procollagen in myelofibrosis
30. Immunoenzymatic detection of fibronectin in normal and pathological haematopoietic tissue
31. Tenascin immunoreactivity in normal and pathological bone marrow
32. Vitronectin (serum spreading factor) its localisation in normal and fibrotic tissue
33. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix
34. Tenascin: cDNA cloning and induction by TGF-β
35. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor
36. Transforming growth factor β induction of type-I plasminogen activator inhibitor
37. Transforming growth factor-β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation
38. Vascular architecture of collagen type IV in primary myelofibrosis and poly-cythaemia vera: an immunomorphometric study of trephine biopsies of the bone marrow
39. Role of transforming growth factor-β in repair and fibrosis
40. Correlation of fibrosis and transforming growth factor-β type 2 levels in the eye
41. Transforming growth factors β1 and α in chronic liver disease: effects of interferon alfa therapy
42. Transforming growth factor β1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis
43. Colocalization of transforming growth factor-β2 with α1 (I) procollagen mRNA in tissue sections of patients with systemic sclerosis
44. The production of transforming growth factor-β in acute megakaryoblastic leukemia and its possible implication in myelofibrosis
45. Characterisation of an acute micromegakaryocytic leukaemia: evidence for the pathogenesis of myelofibrosis
46. Immunolocalization of platelet-derived growth factor, transforming growth factor-β, and fibronectin in acute megakaryoblastic leukemia manifesting tumor formation
47. Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor-β in patients with myelofibrosis with myeloid metaplasia
48. Reduced responsiveness of bone marrow megakaryocyte progenitors to platelet-derived transforming growth factor-β1 produced in normal amounts in patients with essential thrombocythaemia
49. Interferon gamma in vivo reverses the increased platelet levels of platelet-derived growth factor and transforming growth factor-beta in patients with myelofibrosis with myeloid metaplasia
50. Transforming growth factor-β and megakaryocytes in the pathogenesis of idiopathic myelofibrosis
51. Transforming growth factor β: a matter of life and death
52. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system
53. Mechanism of activation of the TGF-β receptor
54. Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells
55. Modulation of megakaryocytopoiesis by human basic fibroblast growth factor
56. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production
57. Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily
58. Promotion of megakaryocyte progenitor expansion and differentiation by the c-mpl ligand thrombopoietin