Differential induction of IL12 synthesis by Mycobacterium bovis BCG and Listeria monocytogenes

Research in Immunology

Volumn 146, Issue 7-8, 1995, Pages 520-526

  Flesch, I E A ^a   Kaufmann, S H E ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; INTERLEUKIN 12; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; INFECTION; LISTERIA MONOCYTOGENES; MACROPHAGE; MOUSE; MYCOBACTERIUM BOVIS; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; ANIMAL; ARTICLE; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; COMPARATIVE STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; MICROBIOLOGY; MOUSE MUTANT;

ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-12; LISTERIA MONOCYTOGENES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MYCOBACTERIUM BOVIS;

EID: 0029414720     PISSN: 09232494     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-2494(96)83026-4     Document Type: Article

References (15)

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2. Mycobacterial growth inhibition by interferon-γ-activated bone marrow macrophages and differential susceptibility among strains of Mycobacterium tuberculosis
3. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon-γ and tumor necrosis factor α
4. + T cells through IL-12 produced by Listeria-induced macrophages
5. Immune response in mice that lack the interferon-γ receptor
6. Immunity to intracellular bacteria
7. Interleukin 12 in host defense against microbial pathogens
8. Monoclonal antibody to gamma interferon inhibits lymphokineinduced antiviral and macrophage tumoricidal activities
9. Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective T helper type 1 immune response
10. Detection of individual mouse splenic T cells producing IFNγ and IL-5 using the enzyme-linked immunospot (ELIS-POT) assay
11. Interleukin-12: A proinfammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
12. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
13. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
14. IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-γ
15. Interleukin12 and tumor necrosis factor α are costimulators of interferon-γ production by natural killer cells in severe combined immunodeficiency mice with Listeriosis, and interleukin 10 is a physiologic antagonist