-
4
-
-
0024536654
-
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
-
(1989)
Science
, vol.244
, pp. 217-221
-
-
Baker, S.J.1
Fearon, E.R.2
Nigro, J.M.3
Hamilton, S.R.4
Preisinger, A.C.5
Jessup, J.M.6
van Tuinen, P.7
Ledbetter, D.H.8
Barker, D.F.9
Nakamura, Y.10
White, R.11
Vogelstein, B.12
-
12
-
-
0023914874
-
Gene amplification in malignant human gliomas: Clinical and histopathological aspects
-
(1988)
J. Neuropathol. Exp. Neurol.
, vol.47
, pp. 191-205
-
-
Bigner, S.H.1
Burger, P.C.2
Wong, A.J.3
Werner, M.H.4
Hamilton, S.R.5
Muhlbaier, L.H.6
Vogelstein, B.7
Bigner, D.D.8
-
25
-
-
0025935859
-
TP53 gene mutations and 17p deletions in human astrocytomas
-
(1991)
Genes Chromosom. Cancer
, vol.3
, pp. 323-331
-
-
Chung, R.1
Whaley, J.2
Kley, N.3
Anderson, K.4
Louis, D.5
Menon, A.6
Hettlich, C.7
Freiman, R.8
Hedley‐Whyte, E.T.9
Martuza, R.10
Jenkins, R.11
Yandell, D.12
Seizinger, B.R.13
-
33
-
-
0025086953
-
p53 functions as a cell cycle control protein in osteosarcomas
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 5772-5781
-
-
Diller, L.1
Kassel, J.2
Nelson, C.E.3
Gryka, M.A.4
Litwak, G.5
Gebhardt, M.6
Bressac, B.7
Ozturk, M.8
Baker, S.J.9
Vogelstein, B.10
Friend, S.H.11
-
34
-
-
0027210981
-
Gain of function mutations in p53
-
(1993)
Nature Genet.
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.J.8
-
36
-
-
0028220204
-
p53‐dependent inhibition of cyclin‐dependent kinase activities in human fibroblasts during radiation‐induced G1 arrest
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tisty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
38
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor a, and epidermal growth factor and their expression in human gliomas in vivo
-
(1991)
Cancer Res.
, vol.51
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
Seliger, B.4
Petterson, R.F.5
Collins, V.P.6
-
39
-
-
0038726748
-
Loss of distinct regions on the short arm of chromosome 17 associated with tumorigenesis of human astrocytomas
-
(1989)
Proceedings of the National Academy of Sciences
, vol.86
, pp. 7186-7190
-
-
El‐Azouzi, M.1
Chung, R.Y.2
Farmer, G.E.3
Martuza, R.L.4
Black, P.M.5
Rouleau, G.A.6
Hettlich, C.7
Hedley‐Whyte, E.T.8
Zervas, N.T.9
Panagopoulos, K.10
Nakamura, Y.11
Gusella, J.F.12
Seizinger, B.R.13
-
41
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El‐Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
42
-
-
0028294605
-
WAF1/CIP1 is induced in p53‐mediated G1 arrest and apoptosis
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El‐Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
Wiman, K.G.11
Mercer, W.E.12
Kastan, M.B.13
Kohn, K.W.14
Elledge, S.J.15
Kinzler, K.W.16
Vogelstein, B.17
-
48
-
-
0025024469
-
Presence of a potent transcription activating sequence in the p53 protein
-
(1990)
Science
, vol.249
, pp. 1046-1049
-
-
Fields, S.1
Jang, S.K.2
-
49
-
-
0027498314
-
The mdm‐2 oncogene can overcome wild‐type p53 suppression of transformed cell growth
-
(1993)
Mol, Cell Biol.
, vol.13
, pp. 301-306
-
-
Finlay, C.A.1
-
53
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
(1994)
Nature Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
58
-
-
0028137084
-
p53: A glimpse at the puppet behind the shadow play
-
(1994)
Science
, vol.265
, pp. 334-335
-
-
Friend, S.1
-
62
-
-
0025975701
-
Protein synthesis required to anchor a mutant p53 protein which is temperature‐sensitive for nuclear transport
-
(1991)
Nature
, vol.349
, pp. 802-806
-
-
Gannon, J.V.1
Lane, D.P.2
-
65
-
-
0027269545
-
A structural role for metal ions in the “wild‐type” conformation of the tumor suppressor protein p53
-
(1993)
Cancer Res.
, vol.53
, pp. 1739-1742
-
-
Hainaut, P.1
Milner, J.2
-
68
-
-
0024364603
-
Stabilization of the p53 transformation‐related protein in mouse fibrosarcoma cell lines: Effects of protein sequence and intracellular environment
-
(1989)
Mol. Cell. Biolt
, vol.9
, pp. 3385-3392
-
-
Halevy, O.1
Hall, A.2
Oren, M.3
-
71
-
-
0026452949
-
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
-
(1992)
Cell
, vol.71
, pp. 543-546
-
-
Hartwell, L.1
-
74
-
-
0027179908
-
In vitro growth characteristics of embryo fibroblasts isolated from p53‐deficient mice
-
(1993)
Oncogene
, vol.8
, pp. 2457-2467
-
-
Harvey, M.1
Sands, A.T.2
Weiss, R.S.3
Hegi, M.E.4
Wiseman, R.W.5
Pantazis, P.6
Giovanella, B.C.7
Tainsky, M.A.8
Bradley, A.9
Done‐bower, L.A.10
-
79
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
Soussi, T.4
Fuchs, R.5
Sørlie, T.6
Hovig, E.7
Smith‐Sørensen, B.8
Montesano, R.9
Harris, C.C.10
-
87
-
-
0026496885
-
, A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia‐telangiectasia
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El‐Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace, A.J.9
-
90
-
-
0027513655
-
Turcot's syndrome of glioma and polyposis occurs in the absence of germ line mutations of exons 5 to 9 of the p53 Gene
-
(1993)
Cancer Res.
, vol.53
, pp. 957-961
-
-
Kikuchi, T.1
Rempel, S.A.2
Rutz, H.‐P.3
de Tribolet, N.4
Mulligan, L.5
Cavenee, W.K.6
Jothy, S.7
Leduy, L.8
Van Meir, E.G.9
-
93
-
-
0027975755
-
TP53 alterations and clinical outcome in low grade astrocytomas
-
(1994)
Genes, Chromosomes and Cancer
, vol.10
, pp. 143-149
-
-
Kraus, J.A.1
Bolln, C.2
Wolf, H.K.3
Neumann, J.4
Kindermann, D.5
Fimmers, R.6
Forster, F.7
Baumann, A.8
Schlegel, U.9
-
95
-
-
0028221553
-
Germline p53 gene mutations in subsets of glioma patients‐ J
-
(1994)
Natl, Cancer Inst.
, vol.36
, pp. 344-349
-
-
Kyritsis, A.P.1
Bondy, M.L.2
Xiao, M.3
Berman, E.L.4
Cunningham, J.E.5
Lee, P.S.6
Levin, V.A.7
Saya, H.8
-
96
-
-
0027109075
-
p53, guardian of the genome
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
99
-
-
0024431245
-
High incidence of lung, bone, and lymphoid tumors in transgenic mice overxpressing mutant alleles of the p53 oncogene
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3982-3991
-
-
Lavigueur, A.1
Maltby, V.2
Mock, D.3
Rossant, J.4
Pawson, T.5
Bernstein, A.6
-
103
-
-
0003043605
-
Neoplasms of the central nervous system
-
V. T. DeVita, Jr., S. Hellman, S. A. Rosenberg, eds, J.B. Lippincott, Philadelphia
-
(1989)
Cancer: Principles and Practice of Oncology
, pp. 1557-1611
-
-
Levin, V.A.1
Sheline, G.E.2
Gutin, P.H.3
-
106
-
-
0021932240
-
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumors of glial origin
-
(1985)
Nature
, vol.313
, pp. 144-147
-
-
Liberman, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
Whittle, N.7
Waterfield, M.D.8
Ullrich, A.9
Schlessinger, J.10
-
108
-
-
0018760324
-
Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40‐transformed cells and uninfected embryonal cells
-
(1979)
Cell
, vol.17
, pp. 43-48
-
-
Linzer, D.I.H.1
Levine, A.J.2
-
110
-
-
0027386959
-
Comparative study of p53 gene and protein alterations in human astrocytic tumors
-
(1993)
J. Neuropathol. Exp. Neurol.
, vol.52
, pp. 31-38
-
-
Louis, D.N.1
von Deimling, A.2
Chung, R.Y.3
Rubio, M.‐P.4
Whaley, J.M.5
Eibl, R.H.6
Ohgaki, H.7
Wiestler, O.D.8
Thor, A.D.9
Seizinger, B.R.10
-
114
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
118
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
Fraumeni, J.F.4
Nelson, C.E.5
Kim, D.H.6
Kassel, J.7
Gryka, M.A.8
Bischoff, F.Z.9
Tainsky, M.A.10
Friend, S.H.11
-
125
-
-
0025040367
-
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild‐type p53, Proc
-
(1990)
Natl. Acad. Sci. USA
, vol.87
, pp. 6166-6170
-
-
Mercer, W.E.1
Shields, M.T.2
Antin, M.3
Sauve, G.J.4
Appella, E.5
Romano, J.W.6
Ullrich, S.J.7
-
131
-
-
0025731379
-
Cotranslation of activated mutant p53 with wild type drives the wild‐type p53 protein into the mutant conformation
-
(1991)
Cell
, vol.65
, pp. 765-774
-
-
Milner, J.1
Medcalf, E.A.2
-
132
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human box gene
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
134
-
-
0026733635
-
Biochemical properties of the growth suppressor/oncoprotein p53
-
(1992)
Oncogene
, vol.7
, pp. 1673-1680
-
-
Montenarh, M.1
-
138
-
-
27844486987
-
Retinoblastoma
-
7th ed., C. R. Scriver, A. L. Beaudet, W. S., Sly, D. Valley, eds, McGraw‐Hill, New York
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 613-642
-
-
Newsham, I.1
Hadjistilanou, D.2
Cavenee, W.K.3
-
139
-
-
0024387728
-
Mutations in the p63 gene occur in diverse human tumour types
-
(1989)
Nature
, vol.342
, pp. 705-708
-
-
Nigro, J.M.1
Baker, S.J.2
Preisinger, A.C.3
Jessup, J.M.4
Hostetter, R.5
Cleary, K.6
Bigner, S.H.7
Davidson, N.8
Baylin, S.9
Devilee, P.10
Glover, T.11
Coll ins, F.S.12
Weston13
Harris, C.C.14
Vogelstein, B.15
-
140
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
(1976)
Science.
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
142
-
-
0027430022
-
Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system, Mol
-
(1993)
Care.
, vol.8
, pp. 74-80
-
-
Ohgaki, H.1
Eibl, R.H.2
Schwab, M.3
Reichel, M.B.M.L.4
Gehring, M.5
Petersen, I.6
Höll, T.7
Wiestler, O.D.8
Kleihues, P.9
-
151
-
-
0028072520
-
Joining the complex: Cyclin‐dependent kinase inhibitory proteins and the cell cycle
-
(1994)
Cell
, vol.79
, pp. 181-184
-
-
Peter, M.1
Herskowitz, I.2
-
152
-
-
0027673764
-
The p53‐mdm2 autoregulatory feedback loop: A paradigm for the regulation of growth control by p53?
-
(1993)
Bioessays
, vol.15
, pp. 689-690
-
-
Picksley, S.M.1
Lane, D.P.2
-
153
-
-
0003322264
-
Solid tumors of childhood
-
V. T., DeVita, Jr., S. Hellman, S. A. Rosenberg, J.B. Lippincott, Philadelphia
-
(1989)
Cancer: Principles and Practice of Oncology
, pp. 1612-1670
-
-
Pizzo, P.A.1
Horowitz, M.E.2
Poplack, D.G.3
Hays, D.M.4
Kun, L.E.5
-
163
-
-
0028606403
-
Mechanisms of DNA excision repair
-
(1994)
Science
, vol.266
, pp. 1954-1956
-
-
Sancar, A.1
-
168
-
-
0027050648
-
Wild‐type p53 binds to the TATA‐binding protein and represses transcription, Proc
-
(1992)
Natl. Acad. Sci. USA
, vol.89
, pp. 12028-12032
-
-
Seto, E.1
Usheva, A.2
Zambetti, G.P.3
Momand, J.4
Horikoshi, N.5
Weinmann, R.6
Levine, A.J.7
Shenk, T.8
-
170
-
-
0026523778
-
Induction of apoptosis by wild‐type p53 in a human colon tumor‐derived cell line
-
(1992)
Proc. Natl. Acad, Sci, USA
, vol.89
, pp. 4495-4499
-
-
Shaw, P.1
Bovey, R.2
Tardy, S.3
Sahli, R.4
Sordat, B.5
Costa, J.6
-
175
-
-
0028569767
-
Interaction of the p53‐regulated protein Gadd45 with proliferating cell nuclear antigen
-
(1994)
Science
, vol.266
, pp. 1376-1380
-
-
Smith, M.L.1
Chen, I.‐T.2
Zhan, Q.3
Bae, I.4
Chen, C.‐Y.5
Gilmer, T.M.6
Kastan, M.B.7
O'Connor, P.M.8
Fornace, A.J.9
-
178
-
-
0026523234
-
Detection of both mutant and wild‐type p53 protein in normal skin fibroblasts and demonstration of a shared second hit' on p53 in diverse tumors from a cancer‐prone family with Li‐Fraumeni syndrome
-
(1992)
Oncogene
, vol.7
, pp. 987-991
-
-
Srivaatava, S.1
Tong, Y.A.2
Devadas, K.3
Zou, Z.‐Q.4
Sykes, V.W.5
Chen, Y.6
Blattner, W.A.7
Pirollo, K.8
Cheng, E.H.9
-
183
-
-
0025441236
-
p53 interacts with p34cdc2 in mammalian cells: Implications for cell cycle control and oncogenesis
-
(1990)
Oncogene
, vol.5
, pp. 795-801
-
-
Stürzbecher, H.‐W.1
Maimets, T.2
Chumakov, P.3
Brain, R.4
Addison, C.5
Simanis, V.6
Rudge, K.7
Philp, R.8
Grimaldi, M.9
Court, W.10
Jenkins, J.R.11
-
189
-
-
0028606364
-
Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells
-
(1994)
Proc, Natl Acad. Sci. USA
, vol.91
, pp. 9009-9013
-
-
Ueba, T.1
Nosaka, T.2
Takahashi, J.A.3
Shibata, F.4
Florkiewicz, R.Z.5
Vogelstein, B.6
Oda, Y.7
Kikuchi, H.8
Hatanaka, M.9
-
193
-
-
0028117269
-
Analysis of the p53 gene and its expression in human glioblastoma cells
-
(1994)
Cancer Res.
, vol.54
, pp. 649-652
-
-
Van Meir, E.G.1
Kikuchi, T.2
Tada, M.3
Li, H.4
Diserens, A.‐C.5
Wojcik, B.E.6
Huang, H.‐J.S.7
Friedmann, T.8
de Tribolet, N.9
Cavenee, W.K.10
-
195
-
-
0028855751
-
Single‐cell monitoring of growth arrest and morphological changes induced by transfer of wild type p53 alleles into glioblastoma cells
-
(1995)
Proc. Natl. Acad. Sci USA
, vol.92
, pp. 1008-1012
-
-
Van Meir, E.G.1
Roemer, K.2
Diserens, A.‐C.3
Kikuchi, T.4
Rempel, S.A.5
Haas, M.6
Huang, H.‐J.S.7
Friedmann, T.8
de Tribolet, N.9
Cavenee, W.K.10
-
196
-
-
0028175707
-
p63 mutation, expression, and DNA ploidy in evolving gliomas: Evidence for two pathways of progression
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1011-1017
-
-
van Meyel, D.J.1
Ramsay, D.A.2
Casson, A.G.3
Keeney, M.4
Chambers, A.F.5
Cairncross, J.G.6
-
197
-
-
0026629404
-
p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma
-
(1992)
Cancer Res.
, vol.52
, pp. 2987-2990
-
-
von Deimling, A.1
Eibl, R.H.2
Ohgaki, H.3
Louis, D.N.4
von Ammon, K.5
Petersen, I.6
Kleihues, P.7
Chung, R.Y.8
Wiestler, O.D.9
Seizinger, B.R.10
-
198
-
-
0027305401
-
Deletions on the long arm of chromosome 17 in pilocytic astrocytoma
-
(1993)
Acta Neuropathol.
, vol.86
, pp. 81-85
-
-
von Deimling, A.1
Louis, D.N.2
Menon, A.G.3
von Ammon, K.4
Petersen, I.5
Ellison, D.6
Wiestler, O.D.7
Seizinger, B.R.8
-
208
-
-
0027536951
-
p53‐mediated cell death: Relationship to cell cycle control
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 1415-1423
-
-
Yonish‐Rouach, E.1
Grunwald, D.2
Wilder, S.3
Kimchi, A.4
May, E.5
Lawrence, J.‐J.6
May, P.7
Oren, M.8
-
212
-
-
0028351565
-
The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 2361-2371
-
-
Zhan, Q.1
Lord, K.A.2
Alamo, I.3
Hollander, M.C.4
Carrier, F.5
Ron, D.6
Kohn, K.W.7
Hoffman, B.8
Lieberman, D.A.9
Fornace, A.J.10
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