Pharmacologic studies on the mechanism of melatonin‐induced vasorelaxation in rat aorta

Journal of Pineal Research

Volumn 19, Issue 3, 1995, Pages 133-138

  Weekley, L Bruce ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

aorta; melatonin; pharmacology; rat; tension

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ATROPINE; LIDOCAINE; MELATONIN; SUBSTANCE P; TETRODOTOXIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADRENERGIC SYSTEM; ANIMAL; ARTICLE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; MALE; MUSCLE RELAXATION; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; THORACIC AORTA; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; AORTA, THORACIC; ATROPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; LIDOCAINE; MALE; MELATONIN; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE P; SYMPATHOLYTICS; TETRODOTOXIN; VASOACTIVE INTESTINAL PEPTIDE; VASOCONSTRICTION; VASOMOTOR SYSTEM;

EID: 0029384121     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.1995.tb00182.x     Document Type: Article

References (34)

1. In vitro denervation of the portal vein and caudal artery of the rat
2. The effect of intravenous administration of melatonin on cardiovascular parameters of the baboon (Papio ursinus)
3. Melatonin: Origin, control of circadian rhythm and site of action
4. The effect of serotonin, N‐acetyl‐serotonin and melatonin on spontaneous contractions of isolated rat intestine
5. Modulation of sympathetic neurotransmission by melatonin
6. Modulating action of melatonin on serotonin induced aggravation of ethanol ulcerations and changes of mucosal blood flow in rat stomach
7. Melatonin decreases brain serotonin release, arterial pressure and heart rate in rats
8. Presynaptic effects of melatonin on norepinephrine release and uptake in rat pineal gland
9. Distribution of vasoactive intestinal peptide‐ and substance P‐con‐taining nerves originating from neurons of airway ganglia in cat bronchi
10. Diurnal variations in central venous pressure
11. Evidence for direct vasoconstrictor activity of melatonin in “pressurized” segments of isolated caudal artery from juvenile rats
12. The chemistry and pharmacology of local anesthetics
13. Influence of the pineal gland and melatonin on blood flow and evaporative water loss during heat stress in rats
14. Effect of melatonin on the force of spontaneous contractions of in vitro rat small and large intestine
15. Effect of melatonin on uterine contractility
16. The effect of melatonin on pinealectomy‐induced hypertension in the rat
17. Pinealectomy‐induced hypertension in rats
18. Autonomic innervation of pulmonary artery: evidence for a nonadrenergic noncholinergic inhibitory system
19. Release of vasoactive peptides from autonomic and sensory nerves
20. Action of VIP and distribution of its binding sites in vessels used for coronary artery bypass grafts
21. 1125 iodomelatonin binding sites in the heart and lung: A link between the photoperiodic signal, melatonin and the cardiopulmonary system
22. Carcadian rhythms of atrial natriuretic peptide, blood pressure and heart rate in normal subjects
23. Changes in pulmonary mechanics induced by melatonin
24. Differential effects of omega‐conotoxin GV1A and tetrodotoxin on vasoconstrictions evoked by electrical stimulation and nicotinic receptor stimulation in canine isolated perfused splenic arteries
25. Non‐adrenergic non‐cholinergic neural control of the atrial myocardium
26. The inhibitory action of melatonin on the contractile responses to 5‐HT in various isolated vascular smooth muscles
27. Vasorelaxing action of melatonin in rat isolated aorta; possible endothelial dependent relaxation
28. Elevated blood pressure after pinealectomy in the rat
29. Expression of melatonin receptors in arteries involved in thermoregulation
30. Melatonin‐induced relaxation of rat aorta: Interaction with adrenergic agonists
31. Effects of melatonin on pulmonary and coronary vessels are exerted through perivascular nerves
32. Effects of melatonin on isolated pulmonary artery and vein: Role of the vascular endothelium
33. Influence of melatonin on bovine pulmonary vascular and bronchial smooth muscle tone
34. Effect of melatonin on the human electrocardiogram and simple reaction time responses