Mechanisms of splenic clearance of blood cells and particles: towards development of new splenotropic agents

Advanced Drug Delivery Reviews

Volumn 17, Issue 1, 1995, Pages 103-115

  Moghimi, S M ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Filtration; Macrophage; Phagocytosis; Spleen macrophage; Splenic blood flow pathway

Indexed keywords

BLOOD; CELLS; COMPOSITION EFFECTS; CYTOLOGY; DRUG PRODUCTS; FILTRATION; HEMODYNAMICS; MACROMOLECULES; MICROORGANISMS; PARTICLES (PARTICULATE MATTER);

MACROPHAGE; PHAGOCYTOSIS; SPLENIC BLOOD FLOW PATHWAY; SPLENOTROPIC AGENTS;

CONTROLLED DRUG DELIVERY;

LIPOSOME;

COLLOID; DRUG ANALYSIS; DRUG CLEARANCE; DRUG COMPARISON; DRUG DEVELOPMENT; DRUG TARGETING; ENDOTHELIUM CELL; HUMAN; MACROPHAGE; NONHUMAN; PHARMACEUTICS; PHARMACOKINETICS; PRIORITY JOURNAL; REVIEW; SPLEEN; SPLEEN BLOOD FLOW; THROMBOCYTE;

EID: 0029379535     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-409X(95)00043-7     Document Type: Review

References (100)

1. The spleen and pooling of blood cells
2. A scanning electron microscope study of human spleen: relationship between the microcirculation and functions
3. Clinical studies with spleen-specific radiolabelled agents
4. Imaging of spleen
5. The effect of heat on human red cell morphology, fragility, and subsequent survival in vivo
6. Sequestration of heat-treated autologous red cells in the spleen
7. A comparative study of the sequestration of ‘abnormal’ red cells by the spleen
8. Splenic salvage quantified by uptake of heat-damaged radiolabelled red blood cells
9. Use of platelets as drug carriers for the treatment of hematological diseases
10. Liposome-encapsulated ampicillin against Listeria monocytogenes in vivo and in vitro
11. Targeting of heme-oxygenase inhibitors to the spleen markedly increases their ability to diminish bilirubin production
12. The increased efficacy and decreased nephrotoxicity of a cyclosphorine liposome
13. Splenic architecture as reflected in the connective tissue structure of the human spleen
14. Normal histology of the human spleen
15. The role of the sinus wall in the passage of erythrocytes through the spleen
16. Vascular pathways in non-sinusoidal red pulp: an electron microscope study of the cat spleen
17. Species variation in the structure and function of the marginal zone: an electron microscope study of cat spleen
18. Circulating T and B lymphocytes of the mouse. Migratory properties
19. The lymph follicle: a hard nut to crack
20. Lymphocyte subsets in normal human lymphoid tissues
21. Phenotypic expression of B-lymphocytes. 2. Immunoglobulin expression of germinal center cells
22. Different macrophage populations distinguished by means of fluorescent polysaccharides. Recognition and properties of marginal zone-macrophages
23. Marginalzones:the major Bcellcompartmentofratspleens
24. Traffic of T and B lymphocytesinthenormalspleen
25. Microcirculation of the spleen: new concepts, new challenges
26. Anatomical hazards to the passage of erythrocytes through the spleen
27. In vivo microscopy of the spleen
28. A compartmental analysis of the splenic circulation in rat
29. Terminating arterial vessels in red pulp of human spleen: a transmission electron microscopic study
30. Circulatory pathways in the sinusal spleen of the dog, studied by scanning electron microscopy of microcorrosion casts
31. Theintermediatecirculationinthenonsinusalspleenofthe cat, studied by scanning electron microscopy of microcorrosion casts
32. Microcriculation in rat spleen (sinusal), studied by means of corrosion casts, with particular reference to intermediate pathways
33. Microcirculation in mouse spleen (nonsinusal) studied by means of corrosion casts
34. Microcirculatory pathways in normal human spleen, demonstrated by scanning electron microscopy of corrosion casts
35. Responses of the isolated, perfused human spleen to symphathetic nerve stimulation, catecholamines and polypeptides
36. Studies of hematopoietic microenvironment. VII. Neural mechanisms in splenic microvascular regulation in mice
37. Splenic remodelling of red cell surfaces
38. Stress fibers in the splenic sinus endothelium in situ: molecular structure, relationship to the extracellular matrix and contractibility
39. Kinetics of red blood cell passage through interendothelial slits into venous sinuses in rat spleen, analyzed by in vivo microscopy
40. Pitting function of the spleen in malaria: ultra-structural observations
41. Mechanisms of splenic control of murine malaria: reticular cell activation and the development of a blood-spleen barrier
42. Barrier cells
43. Functional architecture of the splenic vein in the human adult
44. Intrasplenicmicrocirculationinratswith acute hemolytic anemia
45. Effect of splenic congestion associated with hemolytic anemia on mortality of rats challenged with Haemophilus influenzae b
46. Effect of splenic congestion associated with haemolytic anemia on filtration of ‘spleen-homing’ microspheres
47. Isolation of human splenic macrophages and lymphocytes by countercurrent centrifugal elutriation
48. Dual origin of mouse spleen macrophages
49. Ontogenic development of macrophage subpopulations and Ia-positive dendriticcellsinfetalandneonatalratspleen
50. Fetal and neonatal development of human spleen: an immuno-histochemical study
51. Marginal zone macrophages identified by a monoclonal antibody: characterization of immuno- and enzyme-histochemical properties and functional capacities
52. Macrophages in hemopoietic and other tissues of the developing mouse detected by monoclonal antibody F4/80
53. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in rat recognized by monoclonal antibodies ED1, ED2 and ED3
54. Glycosyl receptors in macrophage subpopulations of rat spleen and lymph node-A comparative study using neoglycoproteins and monoclonal antibodies ED1, ED2 and ED3
55. Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations
56. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation
57. Murine macrophage scavenger receptor: in vivo expression and function as receptor for macrophage adhesion in lymphoid and non-lymphoid organs
58. Splenic marginal-zone macrophages and marginal metallophils in rats and mice
59. Tolerogenic or immunogenic activity of hapten-conjugated polysaccharides correlated with cellular localization
60. Properties of isolated red pulp macrophages from mouse spleen
61. Antigens in immunity. XVI. A light and electron microscopy study of antigen localization in the rat spleen
62. Studies on the perifollicular region of the rat's spleen
63. Characteristic structure of the splenic white pulp in rats
64. Charaterization of non-lymphoid cells in the white pulp of the mouse: an in vivo and in vitro study
65. In vivo effects of lipopolysaccharide on lymphoid and non-lymphoid cells in the mouse spleen. Migration of marginal metallophils towards the follicle centers
66. A comparison of the metallophilic reticuloendothelial cells to cells containing acid phosphatase and non-specific esterase in the lymphoid nodules of normal and stimulated rat spleens
67. A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells
68. Recognition of oxidatively damagedandapoptoticcellsbyanoxidizedlow density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine
69. Relationship between ageing and the immune system
70. A prospective study of the usefulness of the measurement of platelet-associated IgG for the diagnosis of idiopathic thrombocytopenic purpura
71. Cell-bound autologous immunoglobulin in erythrocyte sub-populationsfrompatientswithsicklecelldisease
72. Studies in cobra venom factor treated rats of antibody coated erythrocyte clearance by the spleen: differentialinfluenceofredbloodcell antigennumberontheinhibitoryeffectsof immune complexes on Fc dependent clearance
73. Studies on NEM-treated erythrocytes clearance in the rabbit, with special reference to the effects of circulating immune complexes
74. The role of the spleen in experimental pneumococcal bacteremia
75. Lymphocyte-RES interactions and their fine-structural correlates
76. Human splenic sinusoidal lining cells express antigens associatedwithmonocytes,macrophages,endothelialcells and T lymphocytes
77. Electron microscopy of the spleen. II. Phagocytosis of colloidal carbon
78. A scanning electron microscopy of the spleen
79. Interaction of liposomes and platelets
80. The binding of phosphatidylglycerol liposomes to rat platelets is mediated by complement
81. Thepathologyofthespleen
82. Splenic alterations in hairy-cell leukemia: an electron microscopic study
83. The spleen as a filter
84. Role of radiolabeled erythrocytes in evaluation of splenic function
85. Tissue specific opsonins for phagocytic cells and their different affinity for cholesterol-rich liposomes
86. Serum opsonins and liposomes: their interaction and opsonophagocytosis
87. Non-phagocytic uptake of intravenously injected microspheres in rat spleen: influence of particle size and hydrophilic coating
88. An investigation of the filtration and the fate of large filtered sterically-stabilized microspheres in rat spleen
89. Activity of amphipathic poly(ethylene glycol)5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavourable for immunoliposome binding to target
90. Large liposomes containing ganglioside GM1 accumulate effectively in spleen
91. Amphipathic poly(ethylene glycol) 5000-stabilized dioleoylphos-phatidylethanolamine liposomes accumulate in spleen
92. Polyamino acid microspheres: preparation, characterization and distribution after intravenous injection in rats
93. Enhanced hepatic clearance of intravenously administered sterically stabilized microspheres in zymosan-stimulated rats
94. Coating particles with a block co-polymer (poloxamine-908) suppresses opsonization but permits the activity of dysopsonins in the serum
95. Activity of GM1 in prolonging the blood circulation time of liposomes depends on animal species
96. Serumopsoninsand phagocytosis of saturated and unsaturated phospholipid liposomes
97. Liposomes in host defense mechanism: a key role for macrophages
98. Macrophage depletion in the rat after intraperitoneal administration of liposome-encapsulated clodronate: depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of Freund's adjuvant
99. A comparative study of vascular arrangements in mammalian spleen
100. Complement-dependent phagocytosis of liposomes: suppression by ‘stealth’ lipids