Neurotrophic Factors: Neurotrophin autocrine loops

Current Biology

Volumn 5, Issue 7, 1995, Pages 723-726

  Davies, Alun M ^a   Wright, Edwina M ^b  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NERVE PROTEIN;

ANIMAL; CELL DEATH; CELL SURVIVAL; CYTOLOGY; NERVE CELL; PHYSIOLOGY; REVIEW; SPINAL GANGLION;

ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL SURVIVAL; GANGLIA, SPINAL; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS;

EID: 0029334824     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(95)00144-8     Document Type: Article

References (15)

1. Role of neurotrophins in successive stages of sensory neuron development
2. Trophic regulation of nerve cell morphology and innervation in the autonomic nervous system
3. Directed expression of NGF to pancreatic beta cells in transgenic mice leads to selective hyper-innervation of the islets
4. The nerve growth factor 35 years later
5. Nerve growth factors (NGF BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons
6. Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family
7. Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
8. Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival
9. A BDNF autocrine loop in adult sensory neurons prevents cell death
10. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia
11. Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
12. Neuronal co-localization of mRNAs for neurotrophins and their receptors in the developing central nervous system suggests a potential for autocrine interactions
13. Coexpression of neurotrophins and their receptors in neurons of the central nervous system
14. Requirement for BDNF in activity-dependent survival of cortical neurons
15. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra