A comparison of the 8-hydroxydeoxyguanosine, chromosome aberrations and micronucleus techniques for the assessment of the genotoxicity of mercury compounds in human blood lymphocytes

Mutation Research - Reviews in Genetic Toxicology

Volumn 340, Issue 2-3, 1996, Pages 175-182

  Ogura, Hiroko ^a   Takeuchi, Toru ^a   Morimoto, Kanehisa ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

8 hydroxydeoxyguanosine; Chromosome aberration; Mercuric chloride; Methylmercuric chloride; Micronuclei

Indexed keywords

8 HYDROXYDEOXYGUANOSINE;

ARTICLE; CHROMOSOME ABERRATION; CYTOTOXICITY; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE; MONONUCLEAR CELL; PRIORITY JOURNAL; TOXICITY TESTING;

EID: 0029313607     PISSN: 01651110     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0165-1110(96)90047-0     Document Type: Article

References (37)

1. Al-Sabti K., Lloyd D.C., Edwards A.A., Stegnar D. A survery of lymphocyte chromosomal damage in Slovenian workers exposed to occupational clastogens. Mutation Res. 280:1992;215-223.
2. Anwar W., Gabal M. Cytogenetic study in workers occupationally exposed to mercury fulminate. Mutagenesis. 6:1991;189-192.
3. Betti C., Davini T., Barale R. Genotoxic activity of methyl mercury chloride and dimethyl mercury in human lymphocytes. Mutation Res. 281:1992;255-260.
4. Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granurocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Invest. 21:(Suppl. 97):1968;77-89.
5. Christie N.T., Costa M. In vitro assassment of the toxicity of metal compounds. IV. Disposition of metals in cells: interactions with membranes, glutathione, metallothionein and DNA. Biol. Trace Element. Res. 6:1984;138-158.
6. Dizdaroglu M. Formation of an 9-hydroxyguanune moiety in deoxyribonucleic acid on γ-irradiation in aqueous solution. Biochemistry. 24:1985;4476-4481.
7. Fenech M., Morley A.A. Measurement of micronuclei in lymphocytes. Mutation Res. 147:1985;29-36.
8. Flora S.D., Bennicelli C., Bagnasco M. Genotoxicity of mercury compounds. A review. Mutation Res. 317:1994;57-79.
9. Floyd R.A. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 11:1990;1447-1450.
10. Franchi E., Loprieno G., Ballardin M., Petrozzi L., Migliore L. Cytogenetic monitoring of fishermen with environmental mercury exposure. Mutation Res. 320:1994;23-29.
11. Ganther H.E. Interaction of vitamin E selenium with mercury and silver. Ann. NY Acad. Sci. 355:1980;212-226.
12. Hanaoka T., Tsugane S., Yamano Y., Takahashi T., Kasai H., Natori Y., Watanabe S. Quanitative analysis of 8-hydroxyguanine in peripheral blood cells: an application for asbestosis patients. Int. Arch. Occip. Environ. Health. 65:1993;s215-217.
13. Kasai H., Nishimura S. Hydroxylation of deoxyguanosine at the C-8 position by polyphenols and aminophenols in the presence of hydrogen peroxide and ferric ion. Gann. 75:1984;565-566.
14. Kasai H., Crain P.E., Kuchino Y., Nishimura S., Ootsuyama A., Tanooka H. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis. 11:1986;1849-1851.
15. Kiyosawa H., Suko M., Okudaira H., Murata K., Nishimura S., Chung M-H., Kasai H., Miyamoto T. Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes. Free Radical Res. Commun. 11:1990;23-27.
16. Kobus K., Turner J., Priestley B., Dreosti I. A comparison of the 8-hydroxydeoxyguanosine and midronucleus techniques for the assessment of x-ray and UV induced genotoxicity. Res. Commun. Chem. Pathol. Pharmacol. 80:1993;249-252.
17. Léonard A., Jacquet P., Lauwerys R.R. Mutagenicity and treatogenicity of mercury compounds. Mutation Res. 114:1983;1-18.
18. Meister S., Anderson M.E. Glutathione. Annu. Rev. Biochem. 52:1983;711-760.
19. Monsalve M.V., Chiappe C. Genetic effects of methylmercury in human chromosome. 1. A cytogenetic study of people exposed through eating contaminated fish. Environ. Mol. Mutagen. 10:1987;367-376.
20. Morimoto K., Iijima S., Koizumi A. Selenite prevents the induction of sister-chromatid exchanges by methyl mercury and mercuric chloride in human whole-blood cultures. Mutation Res. 102:1982;183-192.
21. Nakajima M., Takeuchi T., Morimoto K. Determination of 8-hydroxydeoxyguanosine in human cells under oxygen-free conditions. Carcinogenesis. 1996;. in press.
22. Popescu H.I., Negru L., Lancranjan I. Chromosome aberrations induced by occupational exposure to mercury. Arch. Environ. Health. 34:1979;461-463.
23. Shibutani S., Takeshita M., Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature. 349:1991;431-434.
24. Singh S., Toles J., Reimer D. In vivo induction of sister chromotid exchange (SCEs) during aging in genetic strains of mice. Genetic Sciety of Canada (abstracts) Annual Meeting. 107:1984;100-101.
25. Skerfving S., Hansson K.J., Lindsten J. Chromosome breakage in human exposed to methyl mercury through fish comsumption. Arch. Environ. Health. 21:1970;133-139.
26. Skerfving S., Hansson K., Mangs C., Lindston J., Ryman N. Methylmercury-induced chromosome damage in man. Environ. Res. 7:1974;83-98.
27. Stacey M.H., Kappus H. Cellular toxicity and lipid peroxidation in response to mercury. Toxicol. Appl. Pharmacol. 63:1982;29-35.
28. Suda I., Totoki S., Takahashi H. Degradation of methyl and ethyl mercury into inorganic mercury by oxygen free radical-producing systems' involvement of hydroxyl radical. Arch. Toxicol. 65:1991;129-134.
29. Takeuchi T., Morimoto K. Increased formation of 8-hydroxydeoxyguanosine, an oxidative DNA damage, in lymphoblasts from Fanconi's anemia patients due to possible catalase deficiency. Carcinogenesis. 14:1993;1115-1120.
30. Takeuchi T., Nakajima M., Ohta K., Mure K., Takeshita T., Morimoto K. Evalution of 8-hydroxydeoxyguanosine, a typical oxidative DNA damage, in human leukocytes. Carcinogenesis. 15:1994;1519-1523.
31. Thiriger G. Effects of occupational exposure to mercury vapor on lymphocyte micronuclei. Scand. J. Work Environ. Health. 17:1991;263-268.
32. Verschaeve L., Kirsh-Volders M., Hens L., Susanne C. Comparative in vitro cytogenetic studies in mercury-exposed human lymphocytes. Mutation Res. 157:1985;221-226.
33. Watanabe T., Shimada T., Endo A. Effects of mercury compounds on ovulation and meiotic chromosome division in female golden hamster. Teratology. 25:1982;381-384.
34. Wood M.L., Dizdaroglu M., Gajewski E., Essigmann J.M. Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. Biochemistry. 29:1990;7024-7032.
35. Woods J.S. Attenuation of porphyrinogen oxidation by glutathione in vitro and reversal by porphrinogenic trace metals. Biochem. Biophys. Res. Commun. 152:1988;1428-1434.
36. Woods J.S., Calas C.A., Aicher L.D., Robinson B.H., Mailer C. Stimulation of porphyrinogen oxidation by mercuric ion. I. Edidence of free radical formation in the presence of thiol and hydrogen peroxide. Mol. Pharmacol. 38:1990;253-260.
37. Yamada H., Miyahara T., Kozuka H., Matsuhashi T., Sasaki Y. Potentiating effects of organomercuries on clastogen-induced chromosome aberrations in cultured Chinese hamster cells. Mutation Res. 290:1993;281-291.