Pathway engineering for production of aromatics in Escherichia coli: Confirmation of stoichiometric analysis by independent modulation of AroG, TktA, and Pps activities

Biotechnology and Bioengineering

Volumn 46, Issue 4, 1995, Pages 361-370

  Patnaik, Ranjan ^a   Spitzer, Richard G ^a   Liao, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; ALCOHOLS; AROMATIC COMPOUNDS; CATALYSIS; COLIFORM BACTERIA; CONDENSATION; ENZYMES; GLUCOSE; STOICHIOMETRY; SYNTHESIS (CHEMICAL); XYLOSE;

3 DEOXY D ARABINO HEPTULOSONATE 7 PHOSPHATE; ERYTHROSE 4 PHOSPHATE; ESCHERICHIA COLI; PHENYLALANINE; PHOSPHOENOLPYRUVATE; PHOSPHOTRANSFERASE SYSTEM; PYRUVATE; SUGAR UPTAKE; TRYPTOPHAN;

BIOCHEMICAL ENGINEERING;

3 DEOXYARABINOHEPTULOSONATE 7 PHOSPHATE; AROMATIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; BIOENGINEERING; BIOTECHNOLOGY; ESCHERICHIA COLI; GENETIC ENGINEERING; MOLECULAR CLONING; NONHUMAN;

EID: 0029294180     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.260460409     Document Type: Article

References (28)

1. New approach to tryptophan production by Escherichia coli: Genetic manipulation of composite plasmids in vitro
2. Conversion of D‐glucose into catechol: The no‐so‐common pathway of aromatic biosynthesis
3. Biocatalytic synthesis of aromatics from D‐glucose: The role of transketolase
4. Biocatalysis and nineteenth century organic chemistry: Conversion of D‐glucose into quinoid organics
5. Expression of naphthalene oxidation genes in Escherichia coli results in the biosynthesis of indigo
6. Correlation of theoretical and experimental yields of phenylalanine from non‐growing cells of a rec Escherichia coli strain
7. Molecular cloning of the plasmid RP4 primase region in a multi‐host‐range tacP expression vector
8. Genetic and physiological characterization of Escherichia coli mutants deficient in phosphoenolpyruvate carboxykinase activity
9. Cloning of the pyruvate kinase gene (pyk) of Corynebacterium glutamicum and site‐specific inactivation of pyk in a lysine‐producing Corynebacterium lactofermentum strain
10. Identification and characterization of the tktB gene encoding a second transketolase in Escherichia coli K‐12
11. Metabolic engineering to produce tyrosin or phenylalanine in a tryptophan‐producing Corynebacterium glutamicum strain
12. Phenotypic stability of trp operon recombinant plasmids in Escherichia coli
13. Hyperproduction of tryptophan in Corynebacterium glutamicum by pathway engineering
14. Alteration of the biochemical values in central metabolism of Escherichia coli
15. Use of dinitrosalicylic acid reagent for determination of reducing sugars
16. Production of phenylalanine and organic acids by phosphoenolpyruvate carboxylase‐deficient mutants of Escherichia coli
17. Cloning and nucleotide sequence of the Escherichia coli K‐12 ppsA gene, encoding PEP synthase
18. Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield
19. Stimulation of glucose catabolism in Escherichia coli by a potential futile cycle
20. Energetics of the bacterial phosphotransferase system in sugar transport and regulation of carbon metabolism
21. 3‐Deoxy‐D‐arabino‐heptulo‐sonate‐7‐phosphate Synthase
22. The Vibrio fischeri LuxR protein is capable of bidirectional stimulation of transcription and both positive and negative regulation of the luxR gene
23. Use of regulated cell lysis in a lethal genetic selection in Escherichia coli: Identification of the autoinducer‐binding region of the LuxR protein from Vibrio fischeri ATCC 7744
24. Location of the transketolase (tkt) gene on the Escherichia coli physical map
25. 2‐Keto‐3‐deoxy‐D‐araboheptonic acid 7‐phosphate synthetase
26. Network rigidity and metabolic engineering in metabolic overproduction
27. Use of T7 RNA polymerase to direct expression of cloned genes