Receptors for hla class i molecules in human nk cells

Seminars in Immunology

Volumn 7, Issue 2, 1995, Pages 67-73

  Bottino, C ^a   Vitale, M ^a   Pende, D ^a   Biassoni, R ^a   Moretta, A ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN RECEPTOR;

HUMAN; METABOLISM; NATURAL KILLER CELL; REVIEW;

HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMAN; KILLER CELLS, NATURAL; RECEPTORS, IMMUNOLOGIC;

EID: 0029285670     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1995.0010     Document Type: Article

References (24)

1. Trinchieri G (1989) Biology of natural killer cells. Adv Immunol 47:187
2. Ljunggren HG, Karre K (1986) Experimental strategies and interpretations in the analysis of changes in MHC gene expression during tumor progression. Opposing influences of T cell and natural killer mediated resistance? J Immunogenet 13:141
3. Storkus WJ, Salter RD, Alexander J, Ward FE, Ruis RE, Cresswell P, Dawson JR (1991) Class 1-induced resistance to natural killing: Identification of nonpermissive residues in HLA-A2. Proc Natl Acad Sci USA 88:5989
4. Kaufman DS, Schoon RA, Leibson PJ (1992) Role for major histocompatibility complex class I in regulating natural killer cell-mediated killing of virus-infected cells. Proc Natl Acad Sci USA 89:8337
5. Biassoni R, Falco M, Cambiaggi A, Costa P, Verdiani S, Pende D, Conte R, Di Donato C, Parham P, Moretta L. Single aminoacid substitutions can influence the NK-mediated recognition of HLA-C molecules. Role of rerine-77 and lysine-80 in the target cell protection from lysis mediated by ‘Group 2’ or ‘Group 1’ NK clones. J Exp Med, in press
6. Moretta L, Ciccone E, Mingari MC, Biassoni R, Moretta A (1994) Human NK cells: Origin, clonality, specificity and receptors. Adv Immunol 55:341
7. Ciccone E, Pende D, Viale O, Di Donato C, Tripodi G, orengo AM, Guardiola J, Moretta A, Moretta L (1992) Evidence of a natural killer (NK) cell repertoire for (allo)antigen recognition: Definition of five distinct NK-determined allospecificities in humans. J Exp Med 175:709
8. Moretta A, Bottino C, Pende D, Tripodi G, Tambussi G, Viale O, Orengo A, Barbaresi M, Merli A, Ciccone E, Moretta L (1990) Identification of four subsets of human CD3-CD16+ NK cells by the expression of clonally distributed functional surface molecules. Correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J Exp Med 172:1589
9. Ciccone E, Colonna M, Viale O, Pende D, Di Donato C, Reinherz D, Amoroso A, Jeannet M, Guardiola J, Moretta A, Spies T, Strominger J, Moretta L (1990) Susceptibility or resistance to lysis by alloreactive NK cells is governed by a gene in the human major histocompatibility complex between Bf and HLA-B. Proc Natl Acad Sci USA 87:9794
10. Ciccone E, Viale O, Pende D, Malnati M, Biassoni R, Melioli G, Moretta A, Long EO, Moretta L (1988) Specific lysis of allogeneic cells after activation of CD3-lymphocytes in mixed lymphocyte culture. J Exp Med 168:2403
11. Ciccone E, Pende D, Viale O, Tambussi G, Ferrini S, Biassoni R, Longo A, Guardiola J, Moretta A, Moretta L (1990) Specific recognition of human CD3-CD16+ NK cells requires the expression of an autosomic recessive gene on target cells. J Exp Med 172:47
12. Moretta L, Ciccone E, Moretta A, Hoglund P, Ohlen C, Karre K (1992) Allorecognition by NK cells: Nonself or no self? Immunol Today 13:300
13. Ciccone E, Pende D, Viale O, Di Donato C, Orengo AM, Biassoni R, Verdiani S, Amoroso A, Moretta A, Moretta L (1992) Involvement of HLA class I alleles in NK cell specific functions: Expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2). J Exp Med 176:963
14. Colonna M, Spies T, Strominger JL, Ciccone E, Moretta A, Moretta L, Pende D, Viale O (1992) Alloantigen recognition by human natural killer cells is associated with HLA-C or a closely linked gene. Proc Natl Acad Sci USA 89:7983
15. Christiansen FT, Witt CS, Ciccone E, Townend D, Pende D, Viale O, Abraham LJ, Dawkins RL, Moretta L (1993) Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: Ancestral haplotypes encode particular NK-defined haplotypes. J Exp Med 178:1033
16. Moretta A, Tambussi G, Bottino C, Tripodi G, Merli A, Ciccone E, Pantaleo G, Moretta L (1990) A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 171:695
17. Moretta A, Vitale M, Bottino C, Orengo AM, Morelli L, Augugliaro R, Barbaresi M, Ciccone E, Moretta L (1993) P58 molecules as putative receptors for MHC class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J Exp Med 178:597
18. lck kinase, Eur J Immunol 24:2527-2534
19. Wagtmann N, Biassoni R, Malnati M, Moretta A, Long EO (1994) Purification of a member of the p58 family of putative NK cell surface receptors. Natural Immun 13:195A
20. Kaufman DS, Schoon RA, Leibson PJ (1993) MHC class I expression on tumor targets inhibits natural killer cell-mediated cytotoxicity without interfering with target recognition. J Immunol 150:1429
21. Ciccone E, Pende D, Vitale M, Nanni L, Di Donato C, Bottino C, Morelli L, Viale O, Amoroso A, Moretta A, Moretta L (1994) Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells. Eur J Immunol 24:1003
22. Moretta A, Vitale M, Sivori S, Bottino C, Morelli L, Augugliaro R, Barbaresi M, Pende D, Ciccone E, Lopez-Botet M, Moretta L (1994) Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med 180:545
23. Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL (1994) NKB1: An NK cell receptor involved in the recognition of HLA-B. J Exp Med 180:537
24. Trinchieri G (1994) Recognition of major histocompatibility complex class I antigens by natural killer cells. J Exp Med 180:417