An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality.

Molecular medicine (Cambridge, Mass.)

Volumn 1, Issue 3, 1995, Pages 254-266

  Bianchi, M ^a   Ulrich, P ^a   Bloom, O ^a   Meistrell 3rd , M ^a   Zimmerman, G A ^a   Schmidtmayerova, H ^a   Bukrinsky, M ^a   Donnelley, T ^a   Bucala, R ^a   Sherry, B ^a  

^a PICOWER INST FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CARRAGEENAN; DRUG DERIVATIVE; ENDOTOXIN; ENZYME INHIBITOR; GAMMA INTERFERON; HYDRAZONE DERIVATIVE; LIPOPOLYSACCHARIDE; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SEMAPIMOD;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CHEMICAL STRUCTURE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EDEMA; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MOUSE; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ARGININE; BIOLOGICAL TRANSPORT; CARRAGEENAN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; ENDOTOXINS; ENZYME INHIBITORS; HYDRAZONES; INFLAMMATION; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROARGININE;

MLCS; MLOWN;

EID: 0029258451     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf03401550     Document Type: Article

References (0)