The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by β-amyloid: is NAC a common trigger or target in neurodegenerative disease?

Chemistry and Biology

Volumn 2, Issue 3, 1995, Pages 163-169

  Han, Hogyu ^a   Weinreb, Paul H ^a   Lansbury Jr , Peter T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

NAC; prion; seeding; synuclein; amyloid

Indexed keywords

SCRAPIE PRION;

ALPHA SYNUCLEIN; AMYLOID; AMYLOID BETA PROTEIN; NERVE PROTEIN; SNCA PROTEIN, HUMAN; SYNUCLEIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; CRYSTALLIZATION; ELECTRON MICROSCOPY; HUMAN; INFRARED SPECTROSCOPY; KINETICS; METABOLISM; MOLECULAR GENETICS; NERVE DEGENERATION; PHYSICAL CHEMISTRY; SOLUBILITY; SOLUTION AND SOLUBILITY; SYNAPSE; SYNTHESIS;

ALPHA-SYNUCLEIN; AMINO ACID SEQUENCE; AMYLOID; AMYLOID BETA-PROTEIN; CHEMISTRY, PHYSICAL; CRYSTALLIZATION; HUMANS; KINETICS; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; NERVE DEGENERATION; NERVE TISSUE PROTEINS; SOLUBILITY; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SYNAPSES; SYNUCLEINS;

EID: 0029257497     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/1074-5521(95)90071-3     Document Type: Article

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