Biomedical and biotechnological applications of PEG- and PM-modified proteins

Trends in Biotechnology

Volumn 13, Issue 3, 1995, Pages 86-91

  Inada, Yuji ^a   Furukawa, Makoto ^a   Sasaki, Hideyuji ^a   Kodera, Yoh ^a   Hiroto, Misao ^a   Nishimura, Hiroyuki ^a   Matsushima, Ayako ^a  

^a TOIN UNIVERSITY OF YOKOHAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; BIOTECHNOLOGY; CHEMICAL MODIFICATION; DERIVATIVES; DISEASES; DRUG THERAPY; IMMUNOLOGY; MEDICAL APPLICATIONS; MOLECULAR PHYSICS; ORGANIC SOLVENTS; POLYETHYLENE GLYCOLS; SOLUBILITY;

BIOSTABILITY; BIOTRANSFORMATION PROCESS; IMMUNOREACTIVITY; MOLECULAR PROPERTIES; ORGANIC SYNTHESIS; THERAPEUTIC PROTEINS;

PROTEINS;

ALBUMIN; ANTIBIOTIC AGENT; ASPARAGINASE; BILIRUBIN OXIDASE; CATALASE; FETUIN; GULONOLACTONE OXIDASE; HEMOGLOBIN; HIRUDIN; IMMUNOGLOBULIN; INTERLEUKIN 2; MACROGOL; MYOGLOBIN; OVALBUMIN; PEPTIDE; PROTEIN A; PROTEINASE; PROTEINASE INHIBITOR; PURINE NUCLEOSIDE PHOSPHORYLASE; STREPTOKINASE; SUPEROXIDE DISMUTASE; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; URATE OXIDASE; UROKINASE;

BIOTECHNOLOGY; CEREBROSPINAL FLUID; DRUG CLEARANCE; DRUG DEVELOPMENT; ENZYME ACTIVITY; ENZYME STABILITY; HUMAN; IMMUNOREACTIVITY; PRIORITY JOURNAL; PROTEIN MODIFICATION; REVIEW;

AMINO ACID SEQUENCE; ASPARAGINASE; BIOTECHNOLOGY; DRUG DESIGN; ENZYMES; HUMAN; IMMUNOCONJUGATES; MOLECULAR SEQUENCE DATA; POLYETHYLENE GLYCOLS; PROTEINS; SERUM ALBUMIN, BOVINE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 0029256724     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-7799(00)88912-X     Document Type: Article

References (58)

1. Targeting of urokinase by magnetic force.
2. Modification of E. coli asparaginase with 2,4-bis(O-methoxypolyethylene glycol)-6-chloro-S-triazine(activated PEG2); Disappearance of binding ability towards anti-serum and retention of enzymic activity.
3. Kinetic Basis for Artificially Designing Enzymes
4. Reactions Catalyzed by Peg-Modified α-Chymotrypsin in Organic Solvents. Influence of Water Content and Degree of Modification
5. Synthesis of Enkephalins Using Modified Proteases in Organic Media
6. Cellulase immobilization on Fe3O4 and characterization
7. POLYETHYLENE GLYCOL-MODIFIED HEMATOPORPHYRIN AS PHOTOSENSITIZER