Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast‐like cells (MG63)

Journal of Biomedical Materials Research

Volumn 29, Issue 3, 1995, Pages 389-401

  Martin, J Y ^a,b   Schwartz, Z ^b,c   Hummert, T W ^b   Schraub, D M ^d   Simpson, J ^e   Lankford, J ^f   Dean, D D ^b   Cochran, D L ^b   Boyan, B D ^b  

^a WILFORD HALL MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d Hebrew University Hadassah Faculty of Dental Medicine ^*  (United States)

^e INSTITUT STRAUMANN AG   (Switzerland)

^f SOUTHWEST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUGER ELECTRON SPECTROSCOPY; CELL CULTURE; GROWTH KINETICS; OPTICAL MICROSCOPY; PROTEINS; SCANNING ELECTRON MICROSCOPY; SURFACE ROUGHNESS; SURFACE TREATMENT; SYNTHESIS (CHEMICAL); TITANIUM; X RAY ANALYSIS;

ALKALINE PHOSPHATASE SPECIFIC ACTIVITY; CELL NUMBER; COLLAGENASE DIGESTIBLE PROTEIN (CDP); HUMAN OSTEOBLAST LIKE CELLS (MG63); LASER CONFOCAL MICROSCOPY; SURFACE TOPOGRAPHY;

IMPLANTS (SURGICAL);

ALKALINE PHOSPHATASE; TITANIUM;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA SYNTHESIS; ENZYME ACTIVITY; OSSIFICATION; OSTEOBLAST; PROTEIN SYNTHESIS; PROTEOGLYCAN SYNTHESIS; SURFACE PROPERTY;

ALKALINE PHOSPHATASE; CELL DIFFERENTIATION; CELL DIVISION; COMPARATIVE STUDY; HUMAN; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; PROTEINS; PROTEOGLYCANS; RNA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; SURFACE PROPERTIES; TITANIUM; TUMOR CELLS, CULTURED;

EID: 0029256715     PISSN: 00219304     EISSN: 10974636     Source Type: Journal    
DOI: 10.1002/jbm.820290314     Document Type: Article

References (69)

1. Tissue integrated prosthesis osseointegration in clinical dentistry
2. An investigation of tissue tolerance to titanium metal implants in dogs
3. Osseointegrated titanium implants
4. Titanium and titanium alloys
5. Titanium endosseous implant‐soft tissue interface
6. Clinical, immunological, and bacteriological evaluation of adverse reactions to skin‐penetrating titanium implants in the head and neck region
7. Cell biochemistry in relation to the inflammatory response to foreign materials
8. The tissue response at implant sites
9. Surface science aspects on inorganic biomaterials
10. Biomaterials from a surface science perspective
11. Biomaterial and implant surfaces: A surface science approach
12. The concept of osseointegration and bone matrix expression
13. Effect of glass ceramic and titanium implants on primary calcification during rat tibial bone healing
14. Direct chemical bond of bioactive glass‐ceramic materials to bone and muscle
15. Tissue, cellular and subcellular events at a bone‐ceramic interface
16. In vitro and in vivo interactions of cells with biomaterials
17. Biocompatibility of implant metals in bone tissue culture
18. Comparative study of the canine bone/implant interface in vitro and in vivo
19. Biocompatibility of dental implant materials sputtered onto cell culture dishes
20. Growth of bone‐like tissue on titanium in vitro
21. In vitro cell attachment of osteoblast‐like cells to titanium
22. The bone‐titanium interface in vitro
23. The effect of grinding conditions on the toxicity of cobalt‐chrome‐molybdenum particles in vitro
24. Biological effects of corrosion products from metals
25. The advantages of coated titanium implants prepared by radio frequency sputtering from hydroxyapatite
26. Culture surfaces coated with various implant materials affect chondrocyte growth and differentiation
27. The reactions of bone, connective tissue and epithelium to endosteal implants with titanium sprayed surfaces
28. Influence of surface characteristics on bone integration of titanium implants: A histomorphometric study in miniature pigs
29. Anomalous preferences of cultured macrophages for hydrophobic and roughened substrata
30. An evaluation of variables influencing implant fixation by direct bone apposition
31. Removal torques for polished and rough titanium implants
32. The influence of various titanium surfaces on the interface shear strength between implants and bone
33. The influence of the surface energy and roughness of implants on bone resorption
34. The release of titanium into human bone from a titanium implant coated with plasma‐sprayed titanium
35. Implant fixation improved by close fit
36. Effects of a grooved titanium coated implant surface on epithelial cell behaviour, in vitro and in vivo
37. Titanium‐coated micromachined grooves of different dimensions affect epithelial and connective tissue cells differently in vivo
38. The effects of implant surface topography on the behavior of cells
39. Optimization of surface micromorphology for enhanced osteoblast responses in vitro
40. In vitro connective tissue cell attachment to cpTi
41. Design and surface characteristics of 13 commercially available oral implant systems
42. 1, Alpha, 25‐dihydroxyvitamin D 3 specific regulation of growth, morphology, and fibronectin in a human osteosarcoma cell line
43. 3‐responsive alkaline phosphatase in osteoblast‐like cells (ROS 17/2.8, MG‐63 and MC 3T3) and growth cartilage cells in culture
44. Protein measurement with the folin phenol reagent
45. Alkaline phosphatases
46. Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture
47. Use of a mixture of proteinase‐free collagenases for the specific assay of radioactive collagen in the presence of other proteins
48. Comparison of the effects of a potent synthetic analog of bovine parathyroid hormone with native bPTH‐(1–84) and synthetic bPTH‐(1–34) on bone resorption and collagen synthesis
49. Effects of transforming growth factor β on matrix synthesis by chick growth plate chondrocytes
50. Enhanced extracellular matrix production and mineralization by osteoblasts cultured on titanium surface in vitro
51. Evaluation of connective tissue cell responses to orthopaedic implant materials
52. Development of a new system for evaluating the biocompatibility of implant materials using an osteogenic cell line (MC3T3‐E1)
53. Surface characteristics of dental implant materials
54. Dental implant materials II. Preparative procedures and surface spectroscopic studies
55. Surface analysis and characterization of osseointegrated titanium implants
56. Surface analysis of titanium after sterilization: Role in implant‐tissue interface and bioadhesion
57. Accelerated oxide growth on titanium implants during autoclaving caused by fluoride contamination
58. Characterization of sterilized cp titanium implant surfaces
59. Implant surface preparation
60. Cell adhesion
61. Cellular adhesiveness and extracellular substrata
62. Fibroblast growth on a porous collagen sponge containing hyaluronic acid and fibronectin
63. Comments on the clinical application of fibronectin in dentistry
64. Appearance of fibronectin during the differentiation of cartilage, bone and bone marrow
65. Surface properties determine bioadhesive outcomes: Methods and results
66. A light and electron microscopic study of the effects of surface topography on the behavior of cells attached to titanium‐coated percutaneous implants