Eukaryotic DNA methyltransferases – structure and function

BioEssays

Volumn 17, Issue 2, 1995, Pages 139-145

  Adams, Roger L P ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE;

ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; REVIEW;

ANIMAL; DNA MODIFICATION METHYLASES; GENE EXPRESSION REGULATION; SUPPORT, NON-U.S. GOV'T;

EID: 0029169506     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.950170209     Document Type: Review

References (49)

1. The DNA (cytosine‐5) methyltransferases
2. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells
3. Isolation and characterisation of the cDNA encoding human DNA methyltransferase
4. Isolation and identification by sequence homology of a putative cytosine methyltransferase from Arabidopsis thalians
5. Are there two DNA methyltransferase gene families in plant cells?
6. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nucleic
7. Replication factories
8. Direct identification of the active‐site nucleophile in a DNA (cytosine‐5)‐methyltransferase
9. HhaI methyltransferase flips its target base out of the DNA helix
10. Stimulation of de novo methylation following limited proteolysis of mouse ascites DNA methylase
11. Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain
12. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
13. DNA methylation: eukaryotic defence against the transcription of foreign genes?
14. DNA methylation
15. Polymerase chain reaction‐aided genomic sequencing of chromosome‐linked CpG island
16. Non‐CG recognition of DNA cytosine‐5‐methyltransferase from rat liver
17. The majority of methylated cytosines in human DNA are not in the CpG dinucleotide
18. Evidence for cytosine methylation of non‐symmetrical sequences in transgenic Petunia hybrida
19. Densely methylated DNA islands in mammalian chromosomal replication origins
20. Steroid hormone dependent changes in DNA methylation and its significance for the activation or silencing of specific genes
21. Intracellular distribution of DNA methyltransferase during the cell cycle
22. Regulation of human thymidine kinase during the cell cycle
23. Growth regulation of mouse DNA methyltransferase gene expression
24. Regulation of de novo methylation
25. DNA methylation in plants: involvement of two different methyltransferases
26. Silence of the genes
27. Temporal and regional changes in DNA methylation in the embryonic, extra‐embryonic and germ cell lineages during mouse embryo development
28. Decrease in DNA methylase activity during preimplantation development in the mouse
29. Methylation levels of maternal and paternal genomes during preimplantation development
30. Properties and localisation of DNA methyltransferase in preimplantation mouse embryos
31. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
32. CpG‐rich islands and the function of DNA methylation
33. Demethylation of CpG islands in embryonic cells
34. Replacement of 5‐methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation
35. Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5‐methyldeoxycytidine
36. Sp1 elements protect a CpG island from de novo methylation
37. Methylation and the X‐chromosome
38. X chromosome inactivation and DNA methylation
39. Inactive chromatin spreads from a focus of methylation
40. DNA modification mechanisms and gene activity during development
41. What is hemimethylated DNA?
42. Spreading of DNA methylation across integrated foreign (adenovirus type 12) genomes in mammalian cells
43. Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for the involvement of a methyl‐CpG binding protein
44. Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP‐2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site
45. Dissection of the methyl‐CpG binding domain from the chromosomal protein MeCP2
46. The combination of DNA methylation and H1 histone binding inhibits the action of a restriction nuclease on plasmid DNA