A synthetic inhibitor of the mitogen-activated protein kinase cascade

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 17, 1995, Pages 7686-7689

  Dudley, David T ^a   Pang, Long ^a   Decker, Stuart J ^a   Bridges, Alexander J ^a   Saltiel, Alan R ^a  

^a PFIZER INC   (United States)

Author keywords

cell proliferation; growth factor; protein phosphorylation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MICROTUBULE ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHORUS 32; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE INHIBITOR; THYMIDINE; TRITIUM;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KIDNEY CELL; MONOLAYER CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

3T3 CELLS; ALANINE; ANIMAL; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLAVONES; GLUTATHIONE TRANSFERASE; HUMAN; KINETICS; LYSINE; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; RECOMBINANT FUSION PROTEINS; THYMIDINE; TUMOR CELLS, CULTURED;

ANIMALIA; TRITIUM;

EID: 0029166667     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.17.7686     Document Type: Article

References (22)