The nutritional & biological significance of saponins

Nutrition Research

Volumn 15, Issue 8, 1995, Pages 1223-1249

  Milgate, J ^a   Roberts, D C K ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Alfalfa; Bile acids; Hypocholesterolaemia; Medicagenic acid; Neutral sterols; Saponins

Indexed keywords

BILE ACID; CALCIUM; CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT; IRON; SAPONIN; STEROL; ZINC;

ALFALFA; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; COMPLEX FORMATION; DIETARY FIBER; DRUG ACTIVITY; HUMAN; HYPOCHOLESTEROLEMIA; INTESTINE ABSORPTION; MICELLE; NONHUMAN; NUTRITIONAL VALUE; PRIORITY JOURNAL; REVIEW; SOYBEAN; SURFACE TENSION;

EID: 0029166358     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/0271-5317(95)00081-S     Document Type: Review

References (81)

1. Saponins as possible factors of resistance of legume seeds to attack of insects
2. Toxicity of saponins when administered to ruminants
3. The effect of saponins, sterols and linoleic acid on weight increase of growing rats
4. The interactions between dietary saponins cholesterol and related sterols in the chick
5. Soyabean saponins; Studies of their effect on birds, mammals and cold blooded organisms
6. The chemistry and biological significance of saponins in foods and feeding stuffs
7. Isolation of hederagenin & its saponin from alfalfa
8. Zahnic acid tridesmoside & other dominant saponins from alfalfa aerial parts
9. Interaction of lucerne saponins with sterols
10. The effects of alfalfa on serum cholesterol and in modifying cholesterol induced atherosclerosis in rabbits
11. Quantitative relationships between administered cholesterol and alfalfa required to prevent hypercholesterolemia in rabbits
12. Effect of Ileal bypass & alfalfa on hypercholesterolemia
13. Effect of alfalfa saponins on intestinal cholesterol absorption in rats
14. Adsorption of bile salts from aqueous solution by plant fibre and cholestyramine
15. Dietary fibre and other factors in hypercholesterolemia
16. Prevention of elevated cholesterolemia in monkeys
17. Alfalfa Seeds
18. Comparative effects of alfalfa saponins and alfalfa fibre on cholesterol absoption in rats
19. Alfalfa saponins and alfalfa seeds-dietary effects in cholesterol fed rabbits
20. Plasma cholesterol levels in rabbits fed low fat, low cholesterol diets; effects of dietary proteins, carbohydrates and fibre from different sources
21. The effect of dietary protein source and saponins on serum lipids and the excretion of bile acids and neutral sterols in rabbits
22. Adsorption of bile salts by soyabean flour wheat bran lucerne sawdust & lignin the effect of saponins & other plant constituents
23. Effects of dietary proteins and amino acids on the plasma cholesterol concentrations of rabbits fed cholesterol-free diets
24. Soya saponins, plasma lipids, lipoproteins and fecal bile acids- A double blind cross-over study
25. A trial of the effects of soyabean flour and soyabean saponins on plasma lipids, faecal bile acid and neutral sterols in hypercholesterolemic men
26. Saponins and plasma cholesterol
27. Effect of saponins on bile acid and plasma lipids in the rat
28. Effects of dietary saponins on faecal bile acids and neutral sterols, plasma lipids and lipoprotein turnover in the pig
29. Effects of Quillaja and soya saponins on plasma cholesterol and faecal steroid excretion in the rat
30. Saponin content of food plants and some prepared foods
31. Distribution of saponin in alfalfa protein recovery systems
32. Interactions of alfalfa plant and sprout saponins with cholesterol in vitro and in cholesterol-fed rats
33. Prevention of dietary hypercholesterolaemia by chickpea saponins and navy beans
34. Navy beans and navy bean saponins lower plasma cholesterol concentrations in rats
35. Plasma lipid-lowering and lipogenesis-stimulating actions of ginseng saponins in tumor-bearing rats
36. Plasma lipid-lowering action of ginseng saponins and mechanism of the action
37. Dietary saponins and serum lipids
38. An evaluation of hypocholesterolemic factor of fenugreek seeds in rats
39. Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek
40. Influence of different dietary constituents of beans (Phaseolus vulgaris) on serum and biliary lipids in the rat
41. The effect of an ethanol extract derived from fenugreek on bile acid absorption and cholesterol levels in rats
42. Physical properties of dietary fibre
43. Dietary fibre and plasma lipids
44. Responses of rats and swine to alfalfa saponins
45. The toxicity of alfalfa saponins in rats
46. Cholesterol and bile acid balance in Macaca facicularis
47. Lack of toxicity of alfalfa saponins in Cynomologous macques
48. Pancytopenia during ingestion of alfalfa seeds
49. Diet induced systemic lupus erythematosis (SLE) in primates
50. Elimination of toxicity from diets containing alfalfa seeds
51. Alfalfa seeds lower LDL cholesterol and apolipoprotein B concentrations in patients with type 11 hyperlipoproteinemia
52. Production and biological activity of saponins and canavanine in alfalfa seedlings
53. The biological effects and mode of action of L-canavanine a structural analogue of L-arginine
54. Immune responses of mice to inactivated rabies vaccine administered orally: potentiation by quillaja saponin
55. Influence of saponins on gut permeability and active nutrient transport in vitro
56. A bioassay for alfalfa saponins using the fungus Trichoderma virde
57. Interactions between hemolytic saponins, bile salts and small intestinal mucosa in the rat
58. Forage saponins
59. In vitro studies on saponin-mineral complexation
60. Effects of zinc deficiency on bile acid secretion in the rat
61. Effect of level of alfalfa meal in a corn-soybean meal diet on growing-finishing swine
62. The effect of gypsophila saponins in the diet on mineral status and plasma cholesterol in the rat
63. The effect of saponins on iron and zinc availability
64. Dietary copper and cholesterol metabolism
65. Zinc and cholesterol metabolism
66. Soya saponins and plasma cholesterol
67. Dietary fibre, saponins and plasma cholesterol
68. Could saponins be a useful treatment for hypercholesterolaemia?
69. Investigations of the effects of synthetic saponins on cholesterol absorption and serum cholesterol levels
70. CP-148623 inhibits cholesterol absorption by preventing cholesterol entry into intestinal mucosa
71. Soybean saponins-fate of ingested soybean saponins and the physiological aspect of their hemolytic activity
72. Prevention of hypercholesterolemia in monkeys (Macaca fascicularis) by digitonin
73. Yucca plant saponin in the treatment of hypertension and hypercholesterolemia
74. Effects of dietary saponins on bile acid secretion and plasma cholesterol in the rat
75. Effects of soy protein and saponins on serum, tissue and faeces steroids in rat
76. Effects of soyprotein and saponins on serum and liver cholesterol in rats
77. Saponins and fibre
78. A physico-chemical explanation for the effects of dietary saponins on cholesterol and bile salts metabolism
79. Effect of alfalfa meal on shrinkage(regression) of atherosclerotic plaques during cholesterol feeding in monkeys