Role of short-chain fatty acids in the prevention of colorectal cancer

European Journal of Cancer

Volumn 31, Issue 7-8, 1995, Pages 1077-1080

  Scheppach, W ^a   Bartram, H P ^a   Richter, F ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; INTERLEUKIN 2; PROPIONIC ACID; SHORT CHAIN FATTY ACID;

CELL PROLIFERATION; CHEMOPROPHYLAXIS; COLORECTAL CANCER; DIETARY FIBER; GROWTH INHIBITION; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACOLOGY; PRECANCER; PRIORITY JOURNAL; RAT; REVIEW;

ANIMAL; BUTYRATES; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DIET; FATTY ACIDS, VOLATILE; HUMAN; RATS; TUMOR CELLS, CULTURED;

EID: 0029165984     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-8049(95)00165-F     Document Type: Article

References (29)

1. The colonic flora, fermentation, and large bowel digestive function
2. The effect of starch malabsorption on fecal short-chain fatty acid excretion in man
3. Butyrate production from dietary fibre and protection against large bowel cancer in a rat model
4. Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: an association of high acetate and low butyrate ratios with adenomatous polyps and colon cancer
5. Effect of short-chain fatty acids on the human colonic mucosa in vitro
6. Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors
7. Mediation of the trophic effects of short-chain fatty acids on the rat jejunum and colon
8. Colonie fermentation and nutritional recovery in rats with massive small bowel resection
9. Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH
10. Antagonistic effects of deoxycholic acid and butyrate on epithelial cell proliferation in the proximal and distal human colon
11. Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer
12. Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
13. Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells
14. Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29
15. Induction of carcinoembryonic antigen-gene expression in human colorectal carcinoma by sodium butyrate
16. Effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on glycolipids of human rectal adenocarcinoma cells
17. Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase
18. Transcriptional regulation of the human placental-like alkaline phosphatase gene and mechanisms involved in its induction by sodium butyrate
19. ontrasting effects of butyrate on the expression of phenotypic markers of differentiation in neoplastic and non-neoplastic colonic epithelial cells in vitro
20. Effects of sodium butyrate on the synthesis and methylation of DNA in normal cells and their transformed counterparts
21. Acetylation and calcium dependent phosphorylation of histone H3 in nuclei from butyratetreated HeLa cells
22. Effect of butyrate on gene expression
23. Molecular analysis of sodium butyrate-induced growth arrest
24. -lck associated with butyrateinduced differentiation of human colon carcinoma cells
25. Secretion of urokinase and plasminogen activator inhibitor-1 by normal colonic epithelium in vitro
26. Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis
27. Butyrate is a potent inhibitor of urokinase secretion by normal colonic epithelium in vitro
28. An interleukin 2/sodium butyrate combination as immunotherapy for rat colon cancer peritoneal carcinomatosis
29. A genetic model for colorectal tumorigenesis