Use of a recombinant Trypanosoma cruzi protein antigen to monitor cure of Chagas disease

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 89, Issue 4, 1995, Pages 447-448

  Guevara, A G ^a,b   Taibi, A ^a   Alava, J ^c   Guderian, R H ^b   Ouaissi, O ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

^b HOSPITAL VOZANDES   (Ecuador)

^c UNIVERSIDAD TÉCNICA DE MANABÍ   (Ecuador)

Author keywords

Antigen; Chagas disease; Monitoring cure; Trypanosoma cruzi

Indexed keywords

ANTITRICHOMONAL AGENT; BENZNIDAZOLE; PARASITE ANTIGEN; RECOMBINANT PROTEIN;

ARTICLE; CASE REPORT; CHAGAS DISEASE; ECUADOR; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOFLUORESCENCE TEST; MONITORING; TRYPANOSOMA CRUZI;

ACUTE DISEASE; ANIMAL; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CHAGAS DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; NITROIMIDAZOLES; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0029165912     PISSN: 00359203     EISSN: 18783503     Source Type: Journal    
DOI: 10.1016/0035-9203(95)90052-7     Document Type: Article

References (10)

1. Andrade, S. G., Freitas, L. A. R., Peyrol, S., Pimentel, A. R. & Sadigursky, M. (1988). Trypanosoma cruzi antigens detected by immunoelectron microscopy in the spleen of mice serologically positive but parasitologically cured by chemotherapy. Revista da Sociedade Brasileira de Medicina Tropical, 21, 41-42.
2. Brener, Z. (1979). Present status of chemotherapy and chemoprophylaxis of human trypanosomiasis in the western hemisphere. In: Pharmaceutical Therapy, Jaffe, J. J. (editor). New York: Pergamon, pp. 71-90.
3. Camargo, M. E. & Funayama, G. K. (1979). Diagnostico de la-boratorio. In: Trypanosoma cruzi e Doenga de Chagas, Brener, Z. & Andrade, Z. (editors). Rio de Janeiro: Editora Guanabara, pp. 175-198.
4. Castro, S. L. de (1993). The challenge of Chagas’ disease chemotherapy: An update of drugs assayed against Trypanosoma cruzi. Acta Tropica, 53, 83-89.
5. Galvao, L. M. C., Nunes, R. M. B., Cancado, J. R., Brener, Z. & Krettli, A. U. (1993). Lytic antibody titre as a means of assessing cure after treatment of Chagas disease: A 10 years follow-up study. Transactions of the Royal Society of Tropical Medicine and Hygiene, 87, 220-223.
6. Gazzinelli, R. T., Galvao, L. M. C., Cardoso, J. R., Canfado, J. R., Krettli, A. U., Brener, Z. & Gazzinelli, G. (1988). haxi-Trypanosoma cruzi and anti-laminin antibodies in cha-gasic patients after specific treatment. Journal of Clinical Microbiology, 26, 1795-1800.
7. Krautz, G. M., Coutinho, M. G., Galvao, L. M. C., Canfado, J. R. & Krettli, A. U. (1994). Antigenos soluveis liberados por tripomastigotas de Trypanosoma cruzi utilizados no teste de elisa para detectar cura em pacientes chagasicos apos tra-tamento especifico. Revista da Sociedade Brasileira de Medicina Tropical, 27, 199-207.
8. Smith, D. B. & Johnson, K. S. (1988). Single step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene, 67, 31-40.
9. Taibi, A., Plumas-Marty, B., Guevara Esopinoza, A., Scho-neck, R., Pessoa, H., Loyens, M., Piras, R., Aguirre, T., Gras-Masse, H., Bossus, M., Tartar, A., Capron, A. & Ouaissi, A, (1993). Trypanosoma cruzi: Immunity induced in mice and rats by trypomastigote excretory-secretory antigens and identification of a peptide sequence containing a T cell epitope with protective activity. Journal of Immunology, 151, 2676-2689.
10. Taibi, A., Guevara Espinoza, A., Schoneck, R., Yahiaoui, B. & Ouaissi, A. (in press). Improved specificity of Trypanosoma cruzi identification by polymerase chain reaction using an oligonucleotide derived from the amino-terminal sequence of a Tc24 protein. Parasitology.