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1
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0026770377
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Integrins: versatility, modulation, and signaling in cell adhesion
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(1992)
Cell
, vol.69
, pp. 11-25
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Hynes1
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2
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0026938957
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Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information
-
(1992)
Curr Opin Cell Biol
, vol.4
, pp. 772-781
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Damsky1
Werb2
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4
-
-
0027679403
-
Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra and intracellular initiated transmembrane signaling
-
(1993)
Curr Opin Cell Biol
, vol.5
, pp. 819-831
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Sastry1
Horwitz2
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6
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0027445508
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Proteins associated with the cytoplasmic surface of adhesion molecules
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(1993)
Neuron
, vol.11
, pp. 551-564
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-
Gumbiner1
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8
-
-
0028145027
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Adhesive signaling in platelets
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of special interest, A superb, authoritative summary and integration of the large body of knowledge on signaling responses in platelets.
-
(1994)
Curr Opin Cell Biol
, vol.6
, pp. 695-704
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-
Shattil1
Ginsberg2
Brugge3
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9
-
-
0028568948
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Focal adhesion kinase: structure and signalling
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of special interest, A well focused review highlighting new information on the roles of protein kinases associated with focal adhesions, especially focal adhesion kinase.
-
(1994)
J Cell Sci
, vol.18
, pp. 109-113
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-
Parsons1
Schaller2
Hildebrand3
Leu4
Richardson5
Otey6
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10
-
-
0028362351
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Integrating with integrins
-
of special interest, A thought-provoking review that unifies several areas in postulating the important interaction of three types of signals resulting from responses to adhesion, homones/growth factors, and mechanical forces.
-
(1994)
Mol Biol Cell
, vol.5
, pp. 389-393
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-
Schwartz1
Ingber2
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11
-
-
0028335948
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Anchorage dependence, integrins, and apoptosis
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of special interest, A brief, very well-written consideration of the roles of integrins in anchorage dependence of growth and in programmed cell death.
-
(1994)
Cell
, vol.77
, pp. 477-478
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-
Ruoslahti1
Reed2
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12
-
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0028987936
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Integrins and signal transduction pathways: the road taken
-
of outstanding interest, An extremely up-to-date impressive general review of integrin signal transduction, which is based on a broad range of relevant references.
-
(1995)
Science
, vol.268
, pp. 233-239
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-
Clark1
Brugge2
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13
-
-
0029257377
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Signal transduction through integrins: a central role for focal adhesion kinase?
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of special interest, A longer review that [10] that carefully considers the important question of exactly how integrins initiate a signal via kinases; the authors suggest that focal adhesion kinase may be the central molecule recruited by integrins to trigger tyrosine kinase mediated signal transduction.
-
(1995)
Bioessays
, vol.17
, pp. 229-236
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-
Richardson1
Parsons2
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14
-
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0028860240
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Signal transduction by cell adhesion receptors in leukocytes
-
of special interest, A recent review focusing on integrin signaling, with a very timely update on the advantages of the monocyte system for analyzing the integrin signaling pathway from cell surface to the nucleus.
-
(1995)
J Leukoc Biol
, vol.57
, pp. 189-198
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-
Rosales1
Juliano2
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15
-
-
84910921839
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Integrin-dependent signal transduction
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of special interest, A particularly current review on important aspects of integrin signaling, with special emphasis on its culmination in altered gene expression.
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(1995)
J Cell Biochem
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Lafrenie1
Yamada2
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20
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0028927484
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Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
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of special interest, An intriguing in vivo study of the specific role of basement membrane in suppressing apoptosis of mammary epithelial cells; the authors implicate interleukin-1β converting enzyme (ICE) as a key intermediary that is negatively regulated by integrins.
-
(1995)
Science
, vol.267
, pp. 891-893
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-
Boudreau1
Sympson2
Werb3
Bissell4
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21
-
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0027176804
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Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown
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(1993)
J Cell Biol
, vol.121
, pp. 673-678
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McNamee1
Ingber2
Schwartz3
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24
-
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0028954797
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Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
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of outstanding interest, The first evidence for surprisingly distinct functions for integrin occupancy, aggregation, or a synergistic combination of both, in the transmembrane control of cytoskeletal protein accumulation by integrins; provides a novel approach to dissecting integrin function.
-
(1995)
Science
, vol.267
, pp. 883-885
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-
Miyamoto1
Akiyama2
Yamada3
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27
-
-
0028609382
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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
of outstanding interest, A conceptually valuable demonstration of striking parallels of integrin signal transduction pathways to classical growth factor signaling mechanisms, including phosphorylation-mediated Grb2 and c-Src binding to focal adhesion kinase and activation of the mitogen-activated protein kinase signal transduction pathway.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer1
Hanks2
Hunter3
Van der Geer4
-
28
-
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0028801218
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Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.
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of special interest, Identification of surprisingly distinct steps and hierarchies of interactions of signal transduction and cytoskeletal molecules with integrins, which are regulated by integrin aggregation, occupancy, and certain types of tyrosine phosphorylation.
-
(1995)
J Cell Biol
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-
Miyamoto1
Teramoto2
Coso3
Gutkind4
Burbelo5
Akiyama6
Yamada7
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29
-
-
0028817908
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Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex.
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of special interest, A study complementary to [28] that identifies other molecules accumulating in biochemically isolated integrin signalling complexes, including specific components of the inositol lipid pathway and the fibroblast growth factor receptor.
-
(1995)
Mol Biol Cell
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-
Plopper1
McNamee2
Dike3
Bojanowski4
Ingber5
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30
-
-
0028238346
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1 integrin cytoplasmic domain
-
1 integrin tails alone to disrupt cellular adhesion and to induce tyrosine phosphorylation of focal adhesion kinase in the absence of α-subunit tails, particularly after clustering. See also [31].
-
(1994)
J Biol Chem
, vol.269
, pp. 18311-18314
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-
Lukashev1
Sheppard2
Pytela3
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31
-
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0028343192
-
Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimeras
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5 tails also signal, that an alternatively spliced version does not, and that aggregation of the chimeric receptors and their intracellular integrin cytoplasmic domain are important for function.
-
(1994)
J Biol Chem
, vol.269
, pp. 15961-15964
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-
Akiyama1
Yamada2
Yamada3
LaFlamme4
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32
-
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0027967292
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A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK
-
(1994)
J Biol Chem
, vol.269
, pp. 20567-20574
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-
Chan1
Kanner2
Whitney3
Aruffo4
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35
-
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0028296118
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5 cytoplasmic domains in subcellular localization, cell proliferation, and cell migration
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5 tails are more effective in promoting cell migration.
-
(1994)
J Cell Biol
, vol.125
, pp. 447-460
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-
Pasqualini1
Hemler2
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36
-
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0028641601
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Association of insulin receptor substrate-1 with integrins
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of special interest, First demonstration of integrin-specific binding of a signaling intermediate (IRS-1) that binds other signaling molecules such as Grb2 and phosphatidylinositol-3' kinase, associated with an enhancement of DNA synthesis when the cells adhere to vitronectin while stimulated by insulin; it provides further evidence for synergy between integrin and growth factor pathways.
-
(1994)
Science
, vol.266
, pp. 1576-1578
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-
Vuori1
Ruoslahti2
-
39
-
-
0029084316
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Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C.
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of special interest, An intriguing observation that a specific spliced variant of the β1 integrin cytoplasmic domain can play a unique role in the regulation of cellular proliferation; provides an unusually direct link between integrin structure and growth regulation.
-
(1995)
Science
-
-
Meredith1
Takada2
Fornaro3
Languino4
Schwartz5
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45
-
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0020411692
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Immunoelectron microscopic studies of the sites of cell—substratum and cell—cell contacts in cultured fibroblasts
-
(1982)
J Cell Biol
, vol.95
, pp. 205-222
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-
Chen1
Singer2
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46
-
-
0028049088
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Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin
-
(1994)
J Biol Chem
, vol.269
, pp. 704-710
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-
Rankin1
Rozengurt2
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47
-
-
0028053831
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Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells
-
(1994)
J Biol Chem
, vol.269
, pp. 31807-31813
-
-
Matsumoto1
Nakamura2
Kramer3
-
48
-
-
0028036684
-
The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
-
of special interest, This study combined with [21] defines an integrin response pathway that acts by changing levels of a key inositol lipid substrate via an enzyme regulated by the small GTP-binding protein Rho; these findings suggest links between integrin, growth factor, and GTP-binding protein pathways in regulating focal adhesions, the cytoskeleton, and conceivably other aspects of integrin-triggered signaling complexes.
-
(1994)
Cell
, vol.79
, pp. 507-513
-
-
Chong1
Traynor-Kaplan2
Bokoch3
Schwartz4
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49
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes1
Hall2
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50
-
-
0027994108
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Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly
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3B in controlling integrin distribution and mediating cell spreading, migration, and matrix assembly, using quantitative comparisons and dominant-negative suppression of function.
-
(1994)
J Cell Biol
, vol.126
, pp. 1287-1298
-
-
LaFlamme1
Thomas2
Yamada3
Yamada4
-
53
-
-
0029054284
-
Mapping in vivo associations of cytoplasmic proteins with integrin β1 cytoplasmic domain mutants
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of special interest, Although a number of papers have evaluated the roles of integrin cytoplasmic domains on localization to focal adhesions, this study uses anti-integrin antibody-coated beads to induce redistribution of cytoskeletal proteins, thereby establishing that α-actinin alone cannot control actin distribution; provides a new method to examine integrin control of cytoskeletal protein distribution.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 151-160
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-
Lewis1
Schwartz2
-
57
-
-
0028646157
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Augmentation of adherens junction formation in mesenchymal cells by coexpression of NCAM or short-term stimulation of tyrosine-phosphorylation
-
(1994)
Cell Adhesion Commun
, vol.2
, pp. 481-490
-
-
Michalides1
Volberg2
Geiger3
-
58
-
-
0029553517
-
Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions.
-
in press
-
(1995)
Acta Anat (Basel)
-
-
Geiger1
-
60
-
-
0027939187
-
Integrin-mediated cell adhesion activates mitogen-activated protein kinases
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of special interest, First demonstration that integrins can activate a MAP kinase pathway and induce translocation of the activated molecule into the nucleus.
-
(1994)
J Biol Chem
, vol.269
, pp. 26602-26605
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-
Chen1
Kinch2
Lin3
Burridge4
Juliano5
-
62
-
-
0028904784
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Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation
-
(1995)
Mol Biol Cell
, vol.6
, pp. 273-282
-
-
Zhu1
Assoian2
-
64
-
-
0028342810
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Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension
-
(1994)
Biophys J
, vol.66
, pp. 2181-2189
-
-
Wang1
Ingber2
-
65
-
-
0027172919
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Mechanotransduction across the cell surface and through the cytoskeleton
-
(1993)
Science
, vol.260
, pp. 1124-1127
-
-
Wang1
Butler2
Ingber3
-
66
-
-
0029331890
-
Probing transmembrane mechanical coupling and cytomechanics using magnetic twisting cytometry
-
in press
-
(1995)
Biochem Cell Biol
-
-
Wang1
Ingber2
-
68
-
-
0029064234
-
Cytoskeletal filament assembly and the control of cell spreading and function of extracellular matrix
-
(1995)
J Cell Sci
, vol.108
, pp. 2311-2320
-
-
Mooney1
Langer2
Ingber3
-
69
-
-
0028557424
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Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation
-
(1994)
J Cell Sci
, vol.107
, pp. 3643-3654
-
-
Chrzanowska-Wodnicka1
Burridge2
-
71
-
-
0028167979
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β2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils
-
(1994)
J Cell Biol
, vol.126
, pp. 1111-1121
-
-
Berton1
Fumagalli2
Laudanna3
Sorio4
-
73
-
-
0026603414
-
Protein kinase C involvement in focal adhesion formation
-
(1992)
J Cell Sci
, vol.101
, pp. 277-290
-
-
Woods1
Couchman2
-
75
-
-
0028557342
-
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction
-
of special interest, Identifies two distinct signals provided to epithelial cells by extracellular matrix to regulate gene expression: a physical stimulus of signal transduction involving cell shape and a protein-based signal, e.g. by binding of laminin; the response time of the system is markedly accelerated by maintaining an optimal cell shape for signaling.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12378-12382
-
-
Roskelley1
Desprez2
Bissell3
-
76
-
-
0029079272
-
Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals
-
(1995)
J Cell Biol
, vol.129
, pp. 1707-1720
-
-
Tremble1
Damsky2
Werb3
-
78
-
-
0027170760
-
A 50kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells
-
(1993)
J Biol Chem
, vol.268
, pp. 19931-19934
-
-
Schwartz1
Brown2
Fazeli3
-
79
-
-
0027218590
-
Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst
-
(1993)
J Exp Med
, vol.178
, pp. 1165-1174
-
-
Zhou1
Brown2
-
81
-
-
0027079933
-
Fibronectin receptor modulates cyclin-dependent kinase activity
-
(1992)
J Biol Chem
, vol.267
, pp. 25744-25747
-
-
Symington1
-
83
-
-
0028076807
-
Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth
-
(1994)
Mol Biol Cell
, vol.5
, pp. 967-975
-
-
Hansen1
Mooney2
Vacanti3
Ingber4
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