Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: Protective effect against heme and hemoglobin toxicity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 15, 1995, Pages 6798-6802

  Abraham, N G ^a   Lavrovsky, Y ^a   Schwartzman, M L ^a   Stoltz, R A ^a   Levere, R D ^a   Gerritsen, M E ^b   Shibahara, S ^c   Kappas, A ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b BAYER AG   (Germany)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

gene transfer; hemorrhagic toxicity; oxidative stress; vascular endothelium

Indexed keywords

BLOOD CLOTTING FACTOR 8; HEME; HEME OXYGENASE; HEMOGLOBIN; LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CORONARY BLOOD VESSEL; CYTOTOXICITY; DNA TRANSFECTION; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASCULAR ENDOTHELIUM;

ANIMAL; CELLS, CULTURED; CORONARY VESSELS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; ENDOTHELIUM, VASCULAR; FACTOR VIII; HEME; HEME OXYGENASE (DECYCLIZING); HEMOGLOBINS; HEMORRHAGE; HUMAN; LIPOPROTEINS, LDL; OXIDATIVE STRESS; RABBITS; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION;

ANIMALIA; CYTOMEGALOVIRUS; ORYCTOLAGUS CUNICULUS;

EID: 0029156942     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.15.6798     Document Type: Article

References (38)