Suppression of Tumor Growth and Metastasis of Murine Renal Adenocarcinoma by Syngeneic Fibroblasts Genetically Engineered to Secrete the JE/MCP-1 Cytokine

Journal of Interferon and Cytokine Research

Volumn 15, Issue 7, 1995, Pages 655-665

  Huang, Suyun ^a   Xie, Keping ^a   Singh, Rakesh K ^a   Gutman, Mordechai ^a   Bar Eli, Menashe ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CYTOKINE; ENDOTOXIN; LIPOPOLYSACCHARIDE; MACROPHAGE CHEMOTACTIC FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; GENE EXPRESSION; GENETIC ENGINEERING; KIDNEY CARCINOMA; LUNG ALVEOLUS MACROPHAGE; LUNG METASTASIS; MACROPHAGE ACTIVATION; METASTASIS INHIBITION; METASTASIS POTENTIAL; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

3T3 CELLS; ANIMAL; ANTINEOPLASTIC AGENTS; CARCINOMA, RENAL CELL; CELL TRANSPLANTATION; FIBROBLASTS; GENETIC ENGINEERING; HUMAN; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MACROPHAGE ACTIVATION; MICE; MICE, INBRED BALB C; MONOCYTE CHEMOATTRACTANT PROTEIN-1; SUPPORT, U.S. GOV'T, P.H.S.; SUPPRESSION, GENETIC; TRANSFECTION; TRANSPLANTATION, ISOGENEIC; TUMOR CELLS, CULTURED;

EID: 0029155671     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.1995.15.655     Document Type: Article

References (45)

1. SILVERBERT, B.S., and LUBERA, J.A. (1989). Cancer statistics. Cancer J. Clin. 39,3.
2. YAGODA, A. (1989). Chemotherapy of renal cell carcinoma. Semin. Urol. 7,199.
3. SALUP, R.R., HERBERMAN, R.B., and WILTROUT, R.H. (1985). Role of natural killer activity in the development of spontaneous metastasis in murine renal cancer. J. Urol. 134,1236.
4. SALUP, R.R., and WILTROUT, R.H. (1986). Adjuvant immunotherapy of established murine renal cancer by interleukin-2-stimulated lymphocytes. Cancer Res. 46,3358.
5. SALUP, R.R., BACK, T.C., and WILTROUT, R.H. (1987). Successful treatment of advanced murine renal cell cancer by bicompartmental adoptive chemoimmunotherapy. J. Immunol. 138,641.
6. ROSENBERG, S.A., SPIESS, P., and LAFRENIERE, R. (1986). A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science 233,1318.
7. ROSENBERG, S.A., LOTZE, M.T., MUUL, L.M., CHANG, A.E., AVIS, P.P., LEITMAN, S., LINEHAN, W.M., ROBERTSON, C.N., LEE, R.E., RUBIN, J.T., SEIPP, C.A., SIMPSON, C.G., and WHITE, D.E. (1987). A progress report on the treatment of 157 patients with advanced cancer using lymphokine-acti-vated killer cells and interleukin-2 or high interleukin-2 alone. N. Engl. J. Med. 316, 889.
8. WEST, W.H., TAUER, K.W., YANNELLI, J.R., MARSHALL, G.D., and OLDHAM, R.K. (1987). Constant infusion recombinant interleukin-2 in adoptive immunotherapy of advanced cancer. N. Engl. J. Med. 316, 898.
9. SONDEL, P.M., YOUNG, D., LAFORGE, J., COLBORN, D., and NEIDHART, J.A. (1987). Phase I/II trial of interferon-p-serine in patients with renal cell carcinoma: immunological and biological effects. Cancer Res. 47, 2481.
10. SONE, S., MORIGUCHI, S., SHIMIZU, E., OGUSHI, F., and TSUBURA, E. (1982). In vitro generation of tumoricidal properties in human alveolar macrophages following interaction with endotoxin. Cancer Res. 42,2227.
11. FIDLER, I.J. (1988). Targeting of immunomodulators to mononuclear phagocytes for therapy of cancer. Adv. Drug Delivery Rev. 1,69.
12. DINNEY, C.P.N., BUCANA, C.D., UTSUGI, T., FIDLER, I.J., VON ESCHENBACH, A.C., and KILLION, J.J. (1991). Therapy of spontaneous lung metastasis of murine renal adenocarcinoma by systemic administration of liposomes containing the macrophage activator CGP 31362. Cancer Res. 51,3741.
13. FURUTANI, Y., NOMURA, H., NOTAKE, M., OYAMADA, Y., FUKUI, T., YAMADA, M., LARSEN, C.G.G., OPPENHEIM, J.J., and MATSUSHIMA, K. (1989). Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF). Biochem. Biophys. Res. Commun. 159,249.
14. MATSUSHIMA, K., LARSEN, C.G., DUBOIS, C.G., and OPPENHEIM, J.J. (1989). Purification and characterization of a novel monocyte chemotactic protein and activating factor produced by a human myelo-monocytic cell line. J. Exp. Med. 169, 1485.
15. YOSHIMURA, T., YUHKI, N., MOORE, S.K., APPELLA, E., LERMAN, M., and LEONARD, E.J. (1989). Human monocyte chemoattractant protein-1 (MCP-1): full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE. FEBS Lett. 244,487.
16. ZACHARIAE, C.O.C., ANDERSON, A.O., THOMPSON, H.L., APPELLA, E., MANTOVANI, A., OPPENHEIM, J.J., and MATSUSHIMA, K. (1990). Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line. J. Exp. Med. 171,2177.
17. BOTTAZZI, B., COLOTTA, F., SICA, A., NOBILI, N., and MANTOVANI, A. (1990). A chemoattractant expressed in human sarcoma cell (tumor-derived chemotactic factor, TCDF) is identical to monocyte chemoattractant protein-1/monocyte chemotatic and activating factor (MCP-l/MCAF). Int. J. Cancer 45,795.
18. VAN DAMME, J., DECOK, B., BERTINI, R., CONINGS, R., LEANERTS, J.P., PUT, W., OPDENAKKER, G., and MANTOVANI, A. (1991). Production and identification of natural monocyte chemotactic protein (MCP) from virally infected fibroblasts. Relationship with the JE gene product. Eur. J. Biochem. 199,223.
19. COCHRAN, B.H., REFFEL, A.C., and STILES, C.D. (1983). Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell 33,939.
20. ROLLINS, B.J., MORRISON, E.D., and STILES, C.D. (1988). Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc. Natl. Acad. Sci. USA 85,3738.
21. OPPENHEIM, J.J., ZACHARIAE, C.O.C., MUKAIDA, N., and MATSUSHIMA, K. (1991). Properties of the novel proinflammatory supergene “intercrine” cytokine family. Annu. Rev. Immunol. 9,617.
22. BOTTAZZI, B., WALTER, S., GOVONI, D., COLLOTA, F., and MANTOVANI, A. (1992). Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma. J. Immunol. 148, 1280.
23. ROLLINS, B.J., and SUNDAY, M.E. (1991). Suppression of tumor formation in vivo by expression of the JE gene in malignant cells. Mol. Cell Biol. 11,3125.
24. HUANG, S., SINGH, R.K., XIE, K., GUTMAN, M., BERRY, K.K., BUCANA, C.D., FIDLER, I.J., and BAR-ELI, M. (1994). Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells. Cancer Immunol. Immunother. 39,231.
25. SINGH, R.K., BERRY, K.K., MATSUSHIMA, N., MUKAIDA, N., and FIDLER, I.J. (1993). Synergism between human monocyte chemotactic and activating factor (MCAF) and bacterial products for activation of tumoricidal properties in murine macrophages. J. Immunol. 151, 2786.
26. SINGH, R.K., and FIDLER, I.J. (1993). Synergism between human recombinant monocyte chemotactic and activating factor and lipopolysaccharide for activation of antitumor properties in human blood monocytes. Lymphokine Cytokine Res. 12,285.
27. LUCA, M., HUNT, B., BUCANA, C.D., JOHNSON, J.P., FIDLER, I.J., and BAR-ELI, M. (1993). Direct correlation between MUC18 expression and metastatic potential of human melanoma cells. Melanoma Res. 3, 35.
28. RADINSKY, R., FIDLER, I.J., PRICE, J.E., ESUMI, N., TSAN, R., PETTY, C.M., BUCANA, C.D., and BAR-ELI, M. (1994). Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild-type p53. Oncogene 9, 1877.
29. GALLILY, R., and BAR-ELI, M. (1976). Studies on the relationships between the immunogenicity and catabolism of antigens and their binding to the surface of macrophages. Eur. J. Immunol. 6, 789.
30. BAR-ELI, M., and GALLILY, R. (1975). The effect of macrophage hydrolytic enzyme levels on the uptake and degradation of antigen and immune complexes. J. Reticuloendothel. Soc. 18,317.
31. MYRUVIK, A.N., LEAKE, E.S., and FARRIS, B. (1961). Studies on pulmonary alveolar macrophages from normal rabbit: a technique to procure them in a high state of purity. J. Immunol. 86, 128.
32. RAZ, A., FOGLER, W.E., and FIDLER, I.J. (1979). The effect of experimental condition on the expression of in vitro tumor cytotoxicity mediated by murine macrophages. Cancer Immunol. Immunother. 7,157.
33. SAIKI, I., and FIDLER, I.J. (1979). Synergistic activation of recombinant mouse gamma interferon and muramyl dipeptide of tumoricidal properties in mouse macrophages. J. Immunol. 135, 604.
34. SONE, S., and FIDLER, I.J. (1979). In situ activation of tumoricidal properties in rat alveolar macrophages and rejection of experimental lung metastases by intravenous injections of Nocardia rubra cell wall skeleton. Cancer Immunol. Inmiunother. 9,227.
35. YAMASHIRO, S., TAKEYA, M., NISHI, T., KURATSU, J., YOSHIMUA, T., USHIO, Y., and TAKAHASHI, K. (1994). Tumor-derived monocyte chemoattractant protein-1 induces intra-tumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors. Am. J. Pathol. 145,856.
36. WHITWORTH, P.W., PAK, C.C., ESGRO, J., KLEINERMAN, E.S., and FIDLER, I.J. (1990). Macrophages and cancer. Cancer Metastasis Rev. 8,319.
37. MANTOVANI, A. (1990). Tumor-associated macrophages. Curr. Opin. Immunol. 2, 689.
38. NATHAN, C.F. (1987). Secretory products of macrophages. J. Clin. Invest. 78,319.
39. FOLKMAN, J., and KLAGSBURN, M. (1987), Angiogenic factors. Science 235,444.
40. HUANG, S., PAULAISKIS, J.D., GODLESKI, J.J., and KOBZIK, L. (1992). Expression of macrophages inflammatory protein-2 and KC mRNA in pulmonary inflammation. Am. J. Pathol 141,981.
41. XIA, Y.Y., FENG, L.L., YOSHIMURA, T., and WILSON, C.B. (1993). LPS-induced MCP-1, IL-l-beta, and TNF-alpha messenger RNA expression in isolated erythrocyte-perfused rat kidney. Am. J. Physiol. 264,5.
42. WIDNER, U., MANOGUA, K.R., CERAMI, A., SHERRY, B. (1993). Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP-2, MIP-1, and MIP-l-beta), members of the chemokine superfamily of proinflammatory cytokines. J. Immunol. 150,11.
43. OLD, L.J. (1985). Tumor necrosis factor (TNF). Science 230,630.
44. URBAN, J.L., SHEPARD, H.M., ROTHSTEIN, J.L., SUGARMAN, B.J., and SCHREIBER, H. (1986). Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages. Proc. Natl. Acad. Sci. USA 83,5233.
45. XIE, Q.W., and NATHAN, C. (1994). The high-output nitric oxide pathway: role and regulation. J. Leukoc. Biol. 56,576.