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3
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0015984173
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Mutations affecting sexual conjugation and related processes in Saccharomyces cerevisiae. II Genetic analysis of nonmating mutants
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(1974)
Genetics
, vol.76
, pp. 273-288
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MacKay1
Manney2
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4
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0028194848
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Control of meiotic gene expression in Saccharomyces cerevisiae
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(1994)
Microbiol Rev
, vol.58
, pp. 56-70
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-
Mitchell1
-
7
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-
0028012041
-
A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism
-
of outstanding interest, This paper identifies genes regulated by MCM1 by isolation of genomic fragments tightly bound by MCM1 in vitro. An unexpected variety of genes were isolated in this screen, including those involved in controlling cell-cyle progression, the integrity of cell membrane structures, and cellular metabolism.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 348-359
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-
Kuo1
Grayhack2
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11
-
-
0025930897
-
The DNA binding and oligomerization domain of MCM1 is sufficient for its interaction with other regulatory proteins
-
(1991)
EMBO J
, vol.10
, pp. 4209-4218
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Primig1
Winkler2
Ammerer3
-
12
-
-
0028329225
-
MCM1 point mutants deficient in expression of alpha-specific genes: residues important for interaction with alpha 1.
-
of outstanding interest, This paper describes the isolation and anlysis of point mutations affecting a fragment of MCM1 (amino acids 1-98) that carries out all of the cell type regulatory functions. The authors identify amino acids required for DNa binding, interaction with STE12, interaction with α1, and interaction iwth α2. An additional class of mutant proteins was proposed to be deficient in an α1-mediated conformation change. This paper makes important progress towards understanding how a relatively small domain of a regulatory protein can make contact with many different proteins.
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 253-2535
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-
Bruhn1
Sprague2
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13
-
-
0001294043
-
A combinatorial regulatory circuit in budding yeast
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SL McKnight, Kr Yamamoto, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
-
(1992)
Transcriptional Regulation
, pp. 975-1006
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-
Johnson1
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14
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-
0026571502
-
A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an α2 dimer
-
(1992)
Cell
, vol.68
, pp. 133-142
-
-
Smith1
Johnson2
-
16
-
-
0026002757
-
Crystal structure of a MAT α2 homeodomain-operator complex: implications for a general model of homeodomain-DNA interactions
-
(1991)
Cell
, vol.67
, pp. 517-528
-
-
Wolberger1
Vershon2
Liu3
Johnson4
Pabo5
-
18
-
-
0022446158
-
Homeodomain homology in yeast MATα2 is essential for repressor activity
-
(1986)
Nature
, vol.320
, pp. 766-768
-
-
Porter1
Smith2
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19
-
-
0028201030
-
Operator-constitutive mutations in a DNA sequence recognized by a yeast homeodomain
-
(1994)
EMBO J
, vol.13
, pp. 2378-2387
-
-
Smith1
Johnson2
-
20
-
-
0028891623
-
A homeo domain protein lacking specific side chains of helix 3 can still bind DNA and direct transcriptional repression
-
(1995)
Genes Dev
, vol.9
, pp. 182-192
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-
Vershon1
Jin2
Johnson3
-
21
-
-
0027509952
-
A short, disordered protein region mediates interactions between the homeodomain of the yeast α2 protein and the MCM1 protein
-
(1993)
Cell
, vol.72
, pp. 105-112
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-
Vershon1
Johnson2
-
22
-
-
0025804492
-
The CYC8 and TUP1 proteins involved in glucose repression in saccharomyces cerevisae are associated in a protein complex
-
(1991)
Mol Cell Biol
, vol.11
, pp. 3307-3316
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-
Williams1
Varanasi2
Trumbly3
-
23
-
-
84910886089
-
-
Mukai Y, Harashima S, Oshima Y: AARI/TUP1 protein, with a structure similar to that of the ß subunit of G proteins, is required for a1-α2 and α2 repression in cell type control of Saccharomyces cerevisiae. Moll Cell Biol 11:3773-3779.
-
-
-
-
24
-
-
0028034201
-
The WD repeats of Tup1 interact with homeodomain protein α2
-
of special interest, This paper shows that the WD40 repeats of TUP1 interact with α2, providing a direct link between a DNA-binding protein and the SSN6/TUP1 repressor. Negative control mutants of α2, proficient in DNA binding but unable to bring about repression in vivo, disrupt the interaction with TUP1.
-
(1994)
Genes Dev
, vol.8
, pp. 2857-2867
-
-
Komachi1
Redd2
Johnson3
-
26
-
-
0028969881
-
distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters
-
(1995)
Genes Dev
, vol.9
, pp. 821-831
-
-
Tzamarias1
Struhl2
-
30
-
-
0026686185
-
The yeast α1 and MCM1 proteins bind a single strand of their duplex DNA recognition site
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3573-3582
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-
Grayhack1
-
31
-
-
0027330971
-
Transcription of alpha-specific genes in Saccharomyces cerevisiae. DNA sequence requirements for activity of the coregulator α1
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6866-6875
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-
Hagen1
Bruhn2
Westby3
Sprague4
-
32
-
-
0027209343
-
Coupling of cell identity to signal response in yeast-interaction between the α1 and STE12 proteins
-
(1993)
Genes Dev
, vol.7
, pp. 1584-1597
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-
Yuan1
Stroke2
Fields3
-
33
-
-
0025363427
-
DNA binding-induced conformational change of the yeast transcriptional activator PRTF
-
(1990)
Cell
, vol.62
, pp. 367-377
-
-
Tan1
Richmond2
-
34
-
-
0027527069
-
Yeast a1 and α2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein
-
(1993)
J Mol Biol
, vol.233
, pp. 359-371
-
-
Goutte1
Johnson2
-
35
-
-
84910886206
-
Interaction of the homeodomain protein α2 with its corepressor a1
-
University of California, San Francisco, San Francisco
-
(1992)
PhD thesis
-
-
Mak1
-
36
-
-
0028142407
-
Heterodimerization of the yeast homeodomain transcriptional regulators α2 and a1 induces an interfacial helix in α2
-
of outstanding interest, This paper shows that the 20 amino acid tail that extends from the α2 homeodomain contracts the a1 homeodomain when the a1/α2 heterodimer is formed. This interaction converts the tail from a disordered form to an α helix. The a1 protein therefore induces a conformational change in α2.
-
(1994)
Biochemistry
, vol.33
, pp. 9294-9302
-
-
Phillips1
Stark2
Johnson3
Dahlquist4
-
37
-
-
0028272910
-
Heterodimerization of the yeast MATa1 and MAT alpha 2 proteins is mediated by two leucine zipper-like coiled-coil motifs
-
to special interest, This paper proposes that a1 and α2 combine, at least in part, through a coiled-coil interaction that occurs between the amino-terminal domains of the proteins.
-
(1994)
EMBO J
, vol.13
, pp. 1403-1413
-
-
Ho1
Adamson2
Hodges3
Smith4
-
38
-
-
0027496093
-
The carboxy-terminal tail of the homeodomain protein α2 is required for function with a second homeo domain protein
-
(1993)
Genes Dev
, vol.7
, pp. 1862-1870
-
-
Mak1
Johnson2
-
39
-
-
0028021493
-
Interaction between two homeodomain proteins is specified by a short C-terminal tail
-
to special interest, This paper shows that the 20 amino acid tail of α2 can be grafted onto the fly engrailed homeodomain protein to create a new homeodomain—homeodomain combination. It also shows that a1 can recognize the hsg operator in the absence of α2 if the tail is grafted onto a1.
-
(1994)
Nature
, vol.371
, pp. 429-432
-
-
Stark1
Johnson2
-
40
-
-
0028325785
-
Recognition of a DNA operator by a dimer composed of two different homeodomain proteins
-
(1994)
EMBO J
, vol.13
, pp. 1434-1442
-
-
Goutte1
Johnson2
-
41
-
-
0028340797
-
Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex
-
to special interest, This paper shows that a lexA-TUP1 fusion can repress transcription when bound to lexA sites upstream of a yeast promoter. The authors also show that TUP1 contains several independent repression domains.
-
(1994)
Nature
, vol.369
, pp. 758-761
-
-
Tzamarias1
Struhl2
-
42
-
-
0028264386
-
The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure
-
(1994)
Genes Dev
, vol.8
, pp. 1400-1410
-
-
Cooper1
Roth2
Simpson3
-
43
-
-
0027771444
-
Genomic footprinting of the promoter regions of STE2 and STE3 genes in the yeast Saccharomyces cerevisiae
-
(1993)
J Mol Biol
, vol.234
, pp. 975-987
-
-
Ganter1
Tan2
Richmond3
-
44
-
-
0028214089
-
Nucleosomal location of the STE6 TATA box and MATα2p-mediated repression
-
to special interest, This paper shows that repression of the a-specific genes does not require the specific placement of a nucleosome over the TATA box. The authors suggest that the overall chromatin structure (which depends on SSN6/TUP1) contributes to repression.
-
(1994)
Moll Cell Biol
, vol.14
, pp. 4002-4010
-
-
Patterton1
Simpson2
-
45
-
-
0028906077
-
Chromatin-mediated transcriptional repression in yeast
-
(1995)
Curr Opin Genet Dev
, vol.5
, pp. 168-173
-
-
Roth1
-
48
-
-
0029056537
-
The price of repression
-
(1995)
Cell
, vol.81
, pp. 655-658
-
-
Johnson1
-
49
-
-
0028347674
-
An RNA polymerase II holoenzyme responsive to activators
-
(1994)
Nature
, vol.368
, pp. 466-469
-
-
Koleske1
Young2
-
50
-
-
0028937199
-
A kinase-cyclin pair in the RNA polymerase II holoenzyme
-
of special interest, of outstanding interest, This paper shows that the yeast RNA polymerase II holoenzyme contains a kinase (SRB10) and a cyclin (SRB11). See also annotation [52].
-
(1995)
Nature
, vol.374
, pp. 193-196
-
-
Liao1
Zhang2
Jeffery3
Koleske4
Thompson5
Chao6
Viljoen7
Van Vuuren8
Young9
-
51
-
-
0028920526
-
Identification of genes required for α2 repression in Saccharomyces cerevisiae
-
of outstanding interest, to special interest, See annotations [50,52].
-
(1995)
Genetics
, vol.140
, pp. 79-90
-
-
Wahi1
Johnson2
-
52
-
-
0029038690
-
Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast
-
of outstanding interest, to special interest, This paper and [51] show that the kinase and cyclin identified in [50] are required for full repression by the SSN6/TUP1 repressor, suggesting that SSN6/TUP1 may act by modulating the activity of the holoenzyme.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4006-4010
-
-
Kuchin1
Yeghiayan2
Carlson3
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