-
4
-
-
0029038521
-
Regioselectivity and Stereospecificity in a Contrastereoelectronically Controlled Pinacol Rearrangement of Alkoxycyclobutane Derivatives. A Novel Route to Vicinally Substituted Cyclopentanones
-
See also
-
(1995)
The Journal of Organic Chemistry
, vol.60
, pp. 2528-2531
-
-
Patra1
Ghosh2
-
5
-
-
0028046822
-
Enolate free α-alkoxyvinyllithium reagents: Improved preparation and reaction with N,N-dialkylcarboxamides
-
(1994)
Tetrahedron Letters
, vol.35
, pp. 7727-7730
-
-
Shimano1
Meyers2
-
6
-
-
0000839669
-
The Claisen-Johnson Rearrangement Route to 1,4-Dicarbonyl Compounds: Synthesis of Ethyl 4-Ethoxy-4-alkenoates as Masked 4-Oxo Esters
-
(1992)
Synlett
, pp. 217-218
-
-
Bao1
Valverde2
Herradón3
-
13
-
-
0021558291
-
The Homoaldol Reaction, or How to Overcome Problems of Regio- and Stereo-selectivity
-
For a review of the chemistry of metallated enol and allyl carbamates and their use in the homoaldol reaction, see
-
(1984)
Angewandte Chemie International Edition in English
, vol.23
, pp. 932-948
-
-
Hoppe1
-
15
-
-
0000444632
-
-
The selectivity depicted in Scheme 2 was not assigned definitively by the original authors. The only other well documented example of 1,4-induction in a silicon-directed aldol reaction provides the anti-diastereoisomer. See
-
(1990)
J. Org. Chem.
, vol.55
, pp. 3982-3983
-
-
Trost1
Urabe2
-
17
-
-
0002168286
-
REACTIONS OF 2,2,2-TRIFLUOROETHOXY- AND 2 , 2,2-TRIFLUOROETHYLTHIOBENZENE WITH LITHIUM DIALKYLAMIDES. THE FORMATION OF PHENYLTHIOYNAMINES
-
(1976)
Chemistry Letters
, pp. 1263-1266
-
-
Nakai1
Tanaka2
Ishihawa3
-
19
-
-
84913039212
-
A New Synthesis of 1,1-Difluoro-1,3-dienes via the Coupling Reaction of 2,2-Difluorovinylboranes
-
The Ichikawa group has built a substantial oeuvre upon dehydrofluorination/metallation reactions of commercial 2,2,2-trifluoroethyl tosylate. See, for example
-
(1992)
Synlett
, pp. 739-740
-
-
Ichikawa1
Ikeura2
Minami3
-
20
-
-
0038514443
-
A New Fluorine-Containing Acyl Anion Equivalent
-
A preliminary publication has appeared
-
(1992)
Synlett
, pp. 483-484
-
-
Bennett1
Percy2
Rock3
-
22
-
-
84916463150
-
-
The precise significance of the colours is unknown but the absence of colour invariably indicates that the dehydrofluorination/metallation sequence has failed to start and that one or more of the reagents contains water. In the reaction with electrophiles, high yields were obtained despite considerable variation in the “anion” colour.
-
-
-
-
23
-
-
0003417469
-
-
For a discussion, see, Pergamon Press, New York, Chapter 2.3, A true test of the synthetic utility of alkylation reactions of vinyl metal reagents is the alkylation with n-alkyl iodides, allowing functionalised chains to be attached to the vinylic moiety.
-
(1991)
Comprehensive Organic Synthesis
, vol.3
-
-
-
27
-
-
84916516357
-
-
similar result was reported in the desfluoro-system; see ref. 7.
-
-
-
-
29
-
-
84916499087
-
-
1H NMR. Irradiation of the vinylic methyl group resulted in a positive nOe on the methylene protons in the diethylcarbamato group.
-
-
-
-
30
-
-
0001716109
-
A New Acyl Anion Equivalent From Difluoroethanol
-
See, A 2-lithio-E-1-fluoroenol carbamate is sufficiently reactive to be alkylated with iodomethane. The presence of the second fluorine atom therefore appears to be exerting a critical effect upon the reactivity.
-
(1994)
Synlett
, pp. 503-504
-
-
Howarth1
Owton2
Percy3
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