Characterization of ORG 20241, a combined phosphodiesterase IV/III cyclic nucleotide phosphodiesterase inhibitor for asthma

Journal of Pharmacology and Experimental Therapeutics

Volumn 274, Issue 2, 1995, Pages 678-687

  Nicholson, C D ^a   Shahid, M ^a   Bruin, J ^a   Barron, E ^a   Spiers, I ^a   De Boer, J ^a   Van Amsterdam, R G M ^a   Zaagsma, J ^a   Kelly, J J ^a   Dent, G ^a   Giembycz, M A ^a   Barnes, P J ^a  

^a NV ORGANON   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3,4 DIMETHOXYPHENYL) N HYDROXY 2 THIAZOLECARBOXIMIDAMIDE; 6 (5,6 DIMETHOXYBENZO[B]THIEN 2 YL) 4,5 DIHYDRO 5 METHYL 3(2H) PYRIDAZINONE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; HISTAMINE; HYDROGEN PEROXIDE; ISOPRENALINE; LEUKOTRIENE B4; METHACHOLINE; MILRINONE; ORG 20241; PHENYLEPHRINE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM; THROMBOXANE B2; UNCLASSIFIED DRUG;

AIRWAY; ANIMAL TISSUE; AORTA; ARTICLE; ASTHMA; BRONCHUS; CATTLE; DRUG POTENTIATION; ENZYME INHIBITION; EOSINOPHIL; GUINEA PIG; HEART MUSCLE REFRACTORY PERIOD; HEART PAPILLARY MUSCLE; HEART REPOLARIZATION; HUMAN; HUMAN TISSUE; INOTROPISM; MALE; MUSCLE ACTION POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; TRACHEA;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ANIMAL; ASTHMA; CATTLE; GUINEA PIGS; HUMAN; IN VITRO; ISOENZYMES; MALE; MUSCLE, SMOOTH, VASCULAR; PAPILLARY MUSCLES; PHOSPHODIESTERASE INHIBITORS; PYRROLIDINONES; RABBITS; ROLIPRAM; THIAZOLES; TRACHEA;

EID: 0029153656     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)