Use of Sodium Butyrate to Enhance Production of Retroviral Vectors Expressing CFTR cDNA

Human Gene Therapy

Volumn 6, Issue 9, 1995, Pages 1195-1202

  Olsen, John C ^a   Sechelski, John ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; COMPLEMENTARY DNA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYSTIC FIBROSIS; DNA TRANSFECTION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HELPER VIRUS; NONHUMAN; RETROVIRUS; VIRUS REPLICATION;

BUTYRIC ACID; BUTYRIC ACIDS; CLONE CELLS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA, COMPLEMENTARY; GENETIC VECTORS; HUMAN; RETROVIRIDAE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TEMPERATURE; TRANSFECTION; VIRUS REPLICATION;

EID: 0029151439     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.1995.6.9-1195     Document Type: Article

References (42)

1. ADAM, M.A., and MILLER, A.D. (1988). Identification of a signal in a murine retrovirus that is sufficient for packaging of nonretroviral RNA into virions. J. Virol. 62, 3802-3806.
2. ADAM, M.A., RAMESH, N., MILLER, A.D., and OSBORNE, W.R. (1991). Internal initiation of translation in retroviral vectors carrying picomavirus 5’ nontranslated regions. J. Virol. 65, 4985-1990.
3. ANTONI, B.A., RABSON, A.B., KINTER, A., BODKIN, M., and POLI, G. (1994). NF-KB-dependent and-independent pathways of HIV activation in a chronically infected T cell line. Virology 202, 684-694.
4. BAYLE, J. Y., JOHNSON, L.G., GEORGE, J.A.S., BOUCHER, R.C., and OLSEN, J.C. (1993). High efficiency gene transfer to primary monkey airway epithelial cells with retrovirus vectors using the GALV receptor. Hum. Gene Ther. 4, 161-170.
5. BOAT, T.F., WELSH, M.J., and BEAUDET, A.L. (1989). In The Metabolic Basis of Inherited Disease. C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, eds. (McGraw Hill, New York) pp. 2649-2680.
6. BOHAN, C., YERK, D., and SRINTVASAN, A. (1987). Sodium butyrate activates human immunodeficiency virus long terminal repeat-directed expression. Biochem. Biophys. Res. Commun. 148, 899-905.
7. BOHAN, C.A., ROBINSON, R.A., LUCIW, P.A., and SRINTVASAN, A. (1989). Mutational analysis of sodium butyrate inducible elements in the human immunodeficiency virus type I long terminal repeat. Virology 172, 573-583.
8. CARDOSO, J.E., BRANCHEREAU, S., JEYARAJ, P.R., HOUSSIN, D., DANOS, O., and HEARD, J.M. (1993). In situ retrovirus-mediated gene transfer into dog liver. Hum. Gene Ther. 4, 411-418.
9. CHOMCZYNSKI, P. (1992). One-hour downward alkaline capillary transfer for blotting of DNA and RNA. Anal. Biochem. 201, 134-139.
10. CHOMCZYNSKI, P., and SACCHI, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
11. CRYSTAL, R.G. (1995). The gene as a drug. Nature Med. 1, 15-17.
12. DANOS, O., and MULLIGAN, R.C. (1988). Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc. Natl. Acad. Sci. USA 85, 6460-6464.
13. FIELDS-BERRY, S.C., HALLIDAY, A.L., and CEPKO, C.L. (1992). A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. Proc. Natl. Acad. Sci. USA 89, 693-697.
14. FLOTTE, T.R., AFIONE, S.A., CONRAD, C., McGRATH, S.A., SOLOW, R., OKA, H., ZEITLIN, P.L., GUGGINO, W.B., and CARTER, B.J. (1993). Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. Proc. Natl. Acad. Sci. USA 90, 10613-10617.
15. GLAUBER, J.G., WANDERSEE, N.J., LITTLE, J.A., and GINDER, G.D. (1991). 5'-Flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells. Mol. Cell. Biol. 11, 4690-4697.
16. GOLUB, E.I., and VOLSKY, D.J. (1991). Induction of dormant HIV-1 by sodium butyrate: Involvement of the TATA box in the activation of the HIV-1 LTR. AIDS 5, 663-668.
17. JOHNSON, L.G., OLSEN, J.C., SARKADI, B., MOORE, K.L., SWANSTROM, R., and BOUCHER, R.C. (1992). Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis. Nature Genet. 2, 21-25.
18. KOTANI, H., NEWTON III, P.B., ZHANG, S., CHLANG, Y.L., OTTO, E., WEAVER, L., BLAESE, R.M., ANDERSON, W.F., and McGARRITY, GJ. (1994). Improved methods of retroviral vector transduction and production for gene therapy. Hum. Gene Ther. 5, 19-28.
19. LAUGHLIN, M.A., ZEICHNER, S., KOLSON, D., ALWINE, J.C., SESHAMMA, T., POMERANTZ, R.J., and SCARANO, F.G. (1993). Sodium butyrate treatment of cells latently infected with HTV-1 results in the expression of unspliced viral RNA. Virology 196, 496-505.
20. Development of methods for somatic cell gene therapy directed against viral diseases, using retroviral vectors carrying the murine or human interferon-^ coding sequence: Establishment of the antiviral state in human cells, E., LAURET, I., RIVIERE, V., ROUSSEAU, V., VIEILLARD, J., DE MAEYER-GUIGNARD, E., DE MAEYER, Hum. Gene Ther., (1993), 4, 567-577
21. LUKA, J., KALLIN, B., and KLEIN, G. (1979). Induction of the Epstein-Barr virus (EBV) cycle in latently infected cells by n-bu-tyrate. Virology 94, 228-231.
22. LYNCH, C.M., ISRAEL, D.I., KAUFMAN, R.J., and MILLER, A.D. (1993). Sequences in the coding region of clotting factor VHI act as dominant inhibitors of RNA accumulation and protein production. Hum. Gene Ther. 4, 259-272.
23. MARKOWITZ, D., GOFF, S., and BANK, A. (1988). A safe packaging cell line for gene transfer: Separating viral genes on two different plasmids. J. Virol. 62, 1120-1124.
24. MILLER, A.D., and BU X'llMORE, C. (1986). Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol. Cell. Biol. 6, 2895-2902.
25. MILLER, A.D., and ROSMAN, G.J. (1989). Improved retroviral vectors for gene transfer and expression. BioTechniques 7, 980-990.
26. MILLER, A.D., BENDER, M.A., HARRIS, E.A.S., KALEKO, M., and GELINAS, R.E. (1988). Design of retroviral vectors for transfer and expression of the human β-globin gene. J. Virol. 62, 4337-4345.
27. MILLER, A.D., GARCIA, J.V., VON SUHR, N., LYNCH, C.M., WILSON, C., and EIDEN, M.V. (1991). Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus. J. Virol. 65, 2220-2224.
28. OLSEN, J.C., JOHNSON, L.G., STUTTS, M.J., SARKADI, B., YANKASKAS, J.R., SWANSTROM, R., and BOUCHER, R.C. (1992). Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer. Hum. Gene Ther. 3, 253-266.
29. PAUL, R.W., MORRIS, D., HESS, B.W., DUNN, J., and OVERALL, R.W. (1993). Increased viral titer through concentration of viral harvests from retroviral packaging cell lines. Hum. Gene Ther. 4, 609-615.
30. PEAR, W.S., NOLAN, G.P., SCOTT, M.L., and BALTIMORE, D. (1993). Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90, 8392-8396.
31. QUINTON, P. (1990). Cystic fibrosis: A disease in electrolyte transport. FASEB J. 4, 2709-2717.
32. RADSAK, K., FUHRMANN, R., FRANKE, R.P., SCHNEIDER, D., KOLLERT, A., BRUCHER, K.H., and DRENCKHAHN, D. (1989). Induction by sodium butyrate of cytomegalovirus replication in human endothelial cells. Arch. Virol. 107, 151-158.
33. SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T. (1989). Molecular Cloning: A Laboratory Manual. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY).
34. SHADAN, F.F., COWSERT, L.M., and VILLARREAL, L.P. (1994). n-Butyrate, a cell cycle blocker, inhibits the replication of poly-omaviruses and papillomaviruses but not that of adenoviruses and herpesviruses. J. Virol. 68, 4785-4796.
35. STUTTS, M.J., GABRIEL, S.E., OLSEN, J.C., GATZY, J.T., O'CONNELL, T.L., PRICE, E.M., and BOUCHER, R.C. (1993). Functional consequences of heterologous expression of CFTR in fibroblasts. J. Biol. Chem. 268, 20653-20658.
36. TANG, D.C., and TAYLOR, M.W. (1990). Transcriptional activation of the adenine phosphoribosyl transferase promoter by an upstream butyrate-induced Moloney murine sarcoma virus enhancer-promoter element. J. Virol. 64, 2907-2911.
37. TANG, D.C., and TAYLOR, M.W. (1992). Memory of butyrate induction by the Moloney murine sarcoma virus enhancer-promoter element. Biochem. Biophys. Res. Commun. 189, 141-147.
38. WILSON, J.M. (1993). Vehicles for gene therapy. Nature 365, 691-692.
39. YANKASKAS, J.R., HAIZLIP, J.E., CONRAD, M., KOVAL, D., LAZAROWSKI, E., PARADISO, A.M., SCHLEGEL, R., SARKADI, B., and BOUCHER, R.C. (1993). Cystic fibrosis tracheal epithelial cells immortalized by HPV-18 oncogenes retain a well-differentiated phenotype. Am. J. Physiol. (Cell) 264, cl219-cl230.
40. YEE, J.K., MIYANOHARA, A., LAPORTE, P., BOUIC, K., BURNS, J.C., and FRIEDMANN, T. (1994). A general method for the generation of high-titer, pantropic retroviral vectors: Highly efficient infection of primary hepatocytes. Proc. Natl. Acad. Sci. USA 91, 9564-9568.
41. YEIVIN, A., TANG, D.C., and TAYLOR, M.W. (1992). Sodium butyrate selectively induces transcription of promoters adjacent to the MoMSV viral enhancer. Gene 116, 159-164.
42. ZAJAC-KAYE, M., BROWN, E., and FRIEND, C. (1986). Induction of differentiation in Friend erythroleukemia cells with dimethyl sulfoxide, hexamethylene bisacetamide and sodium butyrate is not accompanied by changes in proviral DNA or its expression. Virus Res. 6, 45-55.