메뉴 건너뛰기




Volumn 182, Issue 3, 1995, Pages 699-709

Control of CD4 effector fate: Transforming growth factor β1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0029149596     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.182.3.699     Document Type: Article
Times cited : (149)

References (45)
  • 2
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltavi, Z., C.L. Milliman, and S.J. Korsmeyer. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltavi, Z.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 3
    • 0028032155 scopus 로고
    • Positive selection of lymphocytes
    • Von Boehmer, H. 1994. Positive selection of lymphocytes. Cell 76: 219-228.
    • (1994) Cell , vol.76 , pp. 219-228
    • Von Boehmer, H.1
  • 4
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal, G.J.V. 1994. Negative selection of lymphocytes. Cell. 76: 229-239.
    • (1994) Cell , vol.76 , pp. 229-239
    • Nossal, G.J.V.1
  • 6
    • 0028085152 scopus 로고
    • T and B memory cells
    • Sprent, J. 1994. T and B memory cells. Cell. 76: 315-322.
    • (1994) Cell , vol.76 , pp. 315-322
    • Sprent, J.1
  • 8
    • 0027174660 scopus 로고
    • Memory effectors: A potent, IL4 secreting helper T cell population that develops after restimulation with antigen
    • Bradley, L.M., D.D. Duncan, K. Yoshimoto, and L.S. Swain. 1993. Memory effectors: a potent, IL4 secreting helper T cell population that develops after restimulation with antigen. J. Immunol. 150: 3119-3130.
    • (1993) J. Immunol. , vol.150 , pp. 3119-3130
    • Bradley, L.M.1    Duncan, D.D.2    Yoshimoto, K.3    Swain, L.S.4
  • 9
    • 0026475611 scopus 로고
    • + T cells that provide contact-dependent bystander help to B cells
    • + T cells that provide contact-dependent bystander help to B cells. J. Immunol. 149: 3157-3165.
    • (1992) J. Immunol. , vol.149 , pp. 3157-3165
    • Croft, M.1    Swain, S.L.2
  • 10
    • 0025222698 scopus 로고
    • IL4 directs the development of Th2-like helper effectors
    • Swain, S.L., A.D. Weinberg, M. English, and G. Huston. 1990. IL4 directs the development of Th2-like helper effectors. J. Immunol. 145: 3796-3806.
    • (1990) J. Immunol. , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 11
    • 0027281563 scopus 로고
    • The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory
    • Akbar, A.N., N. Borthwick, M. Salmon, W. Gombert, M, Bofill, N. Shamsadeen, D. Pilling, S. Pett, J.E. Grundy, and G. Janossy. 1993. The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory. J. Exp. Med. 178: 427-438.
    • (1993) J. Exp. Med. , vol.178 , pp. 427-438
    • Akbar, A.N.1    Borthwick, N.2    Salmon, M.3    Gombert, W.4    Bofill, M.5    Shamsadeen, N.6    Pilling, D.7    Pett, S.8    Grundy, J.E.9    Janossy, G.10
  • 12
    • 0027158798 scopus 로고
    • Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
    • Moskophidis, D., F. Lechner, H. Pircher, and R.M. Zinkernagel. 1993. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature (Lond.)▪ 362: 758-761.
    • (1993) Nature (Lond.)▪ , vol.362 , pp. 758-761
    • Moskophidis, D.1    Lechner, F.2    Pircher, H.3    Zinkernagel, R.M.4
  • 14
  • 15
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
    • Wesselborg, S., O. Janssen, and D. Kabelitz. 1993. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J. Immunol. 150: 4338-4345.
    • (1993) J. Immunol. , vol.150 , pp. 4338-4345
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 16
    • 0027264109 scopus 로고
    • Religation of the T cell receptor after primary activation of mature T cell inhibits proliferation and induces apoptotic cell death
    • Radvanyi, L.G., G.B. Mills, and R.G. Miller. 1993. Religation of the T cell receptor after primary activation of mature T cell inhibits proliferation and induces apoptotic cell death. J. Immunol. 150: 5704-5715.
    • (1993) J. Immunol. , vol.150 , pp. 5704-5715
    • Radvanyi, L.G.1    Mills, G.B.2    Miller, R.G.3
  • 17
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse a/j3 T lymphocytes for apoptosis
    • Lenardo, M.J. 1991. Interleukin-2 programs mouse a/j3 T lymphocytes for apoptosis. Nature (Lond.). 353: 858-861.
    • (1991) Nature (Lond.) , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 19
    • 43949165663 scopus 로고
    • Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes
    • Kabelitz D., T. Pohl, and K. Pechhold. 1993. Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes. Immunol. Today. 14: 338-339.
    • (1993) Immunol. Today. , vol.14 , pp. 338-339
    • Kabelitz, D.1    Pohl, T.2    Pechhold, K.3
  • 20
    • 0019732992 scopus 로고
    • Interleukin-2 dependent culture of cytolytic T cell lines
    • Gillis, S., and J. Watson. 1981. Interleukin-2 dependent culture of cytolytic T cell lines. Immunol. Rev. 54: 81-109.
    • (1981) Immunol. Rev. , vol.54 , pp. 81-109
    • Gillis, S.1    Watson, J.2
  • 21
    • 0025775935 scopus 로고
    • Lymphokines and the immune response: The central role of interleukin-2
    • Swain, S.L. 1991. Lymphokines and the immune response: the central role of interleukin-2. Cun. Opin. Immunol 3: 304-310.
    • (1991) Cun. Opin. Immunol , vol.3 , pp. 304-310
    • Swain, S.L.1
  • 22
  • 23
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massague, J. 1990. The transforming growth factor-β family. Annu. Rev. Cell Biol 6: 597-641.
    • (1990) Annu. Rev. Cell Biol , vol.6 , pp. 597-641
    • Massague, J.1
  • 24
    • 0022465625 scopus 로고
    • Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth
    • Kehrl, J.H., L.M. Wakefield, A.B. Roberts, S. Jakowlew, M. Alvarez-Mon, R. Derynck, M.B. Spom, and A.S. Fauci. 1986. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J. Exp Med. 163: 1037-1050.
    • (1986) J. Exp Med. , vol.163 , pp. 1037-1050
    • Kehrl, J.H.1    Wakefield, L.M.2    Roberts, A.B.3    Jakowlew, S.4    Alvarez-Mon, M.5    Derynck, R.6    Spom, M.B.7    Fauci, A.S.8
  • 25
    • 0025104027 scopus 로고
    • TGFβ stimulation and inhibition of cell proliferation: New mechanistic insights
    • Moses, H.L., E.Y. Yang, and J.A. Pietenpol. 1992. TGFβ stimulation and inhibition of cell proliferation: new mechanistic insights. Cell. 63: 245-247.
    • (1992) Cell , vol.63 , pp. 245-247
    • Moses, H.L.1    Yang, E.Y.2    Pietenpol, J.A.3
  • 26
    • 0025951644 scopus 로고
    • TGFb and IL4 direct helper T cell precursors to develop into distinct CD4 helper cells which differ in lymphokine secretion pattern and cell surface phenotype
    • Swain, S.L., G. Huston, S. Tonkonogy, and A.D. Weinberg. 1991. TGFb and IL4 direct helper T cell precursors to develop into distinct CD4 helper cells which differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 147: 2991-3000.
    • (1991) J. Immunol. , vol.147 , pp. 2991-3000
    • Swain, S.L.1    Huston, G.2    Tonkonogy, S.3    Weinberg, A.D.4
  • 27
    • 0025744497 scopus 로고
    • Co-stimulation of T cell proliferation by transforming growth factor-β1
    • Lee, H., and S. Rich. 1991. Co-stimulation of T cell proliferation by transforming growth factor-β1. J. Immunol. 147: 1127-1133.
    • (1991) J. Immunol. , vol.147 , pp. 1127-1133
    • Lee, H.1    Rich, S.2
  • 28
    • 0028518985 scopus 로고
    • Generation and persistence of polarized CD4 cells
    • Swain, S.L. 1994. Generation and persistence of polarized CD4 cells. Immunity. 1: 543-552.
    • (1994) Immunity. , vol.1 , pp. 543-552
    • Swain, S.L.1
  • 29
    • 0025276664 scopus 로고
    • Distinct regulation of lymphokine production is found in fresh versus primed murine helper T cells
    • Weinberg, A.-D., M. English, and S.L. Swain. 1990. Distinct regulation of lymphokine production is found in fresh versus primed murine helper T cells. J. Immunol. 144: 1800-1807.
    • (1990) J. Immunol. , vol.144 , pp. 1800-1807
    • Weinberg, A.-D.1    English, M.2    Swain, S.L.3
  • 30
    • 0023872192 scopus 로고
    • Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4, 5 using modified cDNA expression vectors
    • Karasuyama, H., and F. Melchars. 1988. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4, 5 using modified cDNA expression vectors. Eur. J. Immunol. 18: 97-104.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 97-104
    • Karasuyama, H.1    Melchars, F.2
  • 31
    • 0026738661 scopus 로고
    • + T cells: Dendritic cells are a major antigen-presenting cell
    • + T cells: dendritic cells are a major antigen-presenting cell. J. Exp Med. 176: 1431-1437.
    • (1992) J. Exp Med. , vol.176 , pp. 1431-1437
    • Croft, M.1    Duncan, D.2    Swain, S.L.3
  • 32
    • 0025897022 scopus 로고
    • The accessory function of murine intracellular adhesion molecule-1 in T lymphocyte activation
    • Kuhlman, P., V.T. Moy, B.A. Lollo, and A.A. Brian. 1991. The accessory function of murine intracellular adhesion molecule-1 in T lymphocyte activation. J. Immunol. 146: 1773-1782.
    • (1991) J. Immunol. , vol.146 , pp. 1773-1782
    • Kuhlman, P.1    Moy, V.T.2    Lollo, B.A.3    Brian, A.A.4
  • 34
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and cytometry
    • Nicoletti, I., G. Migliorati, M.C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and cytometry. J. Immunol. Methods. 139: 271-279.
    • (1991) J. Immunol. Methods. , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 35
    • 0027318843 scopus 로고
    • Negative regulation of G1 in mammalian cells: Inhibition of cyclin E-dependent kinase by TGFβ
    • Koff, A., M. Ohsuki, K. Polyak, J.M. Roberts, and J. Massague. 1993. Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGFβ. Science (Wash. DC). 260: 536-539.
    • (1993) Science (Wash. DC). , vol.260 , pp. 536-539
    • Koff, A.1    Ohsuki, M.2    Polyak, K.3    Roberts, J.M.4    Massague, J.5
  • 36
    • 0027374766 scopus 로고
    • TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest
    • Ewen, M.E., K. Sluss, L.L. Whitehouse, and D.M. Livingston. 1993. TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell. 74: 1009-1020.
    • (1993) Cell , vol.74 , pp. 1009-1020
    • Ewen, M.E.1    Sluss, K.2    Whitehouse, L.L.3    Livingston, D.M.4
  • 37
    • 0028179669 scopus 로고
    • p27Kipl, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak, K., J.Y. Kato, M.J. Soloman, C.J. Sherr, J. Massague, J.M. Roberts, and A. Koff. 1994. p27Kipl, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes & Dev. 8: 9-22.
    • (1994) Genes & Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Soloman, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 39
    • 0025273308 scopus 로고
    • Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin
    • Sorenson, C.M., M.A. Barry, and A. Eastman. 1990. Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin. J. Natl. Cancer Inst. 82: 749-755.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 749-755
    • Sorenson, C.M.1    Barry, M.A.2    Eastman, A.3
  • 40
    • 0027182225 scopus 로고
    • Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle
    • Boehme, S.A., and M.J. Lenardo. 1993. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23: 1552-1560.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1552-1560
    • Boehme, S.A.1    Lenardo, M.J.2
  • 42
    • 0026625171 scopus 로고
    • Transforming growth factor-β induces myoblast differentiation in the presence of mitogens
    • Zentella, A., and J. Massague. 1992. Transforming growth factor-β induces myoblast differentiation in the presence of mitogens. Proc. Natl. Acad. Sci. USA. 89: 5176-5180.
    • (1992) Proc. Natl. Acad. Sci. USA. , vol.89 , pp. 5176-5180
    • Zentella, A.1    Massague, J.2
  • 43
    • 0024446350 scopus 로고
    • Transforming growth factor β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes
    • Coffman, R.L., D.A. Lebman, and B. Shrader. 1989. Transforming growth factor β specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J. Exp Med. 170: 1039-1044.
    • (1989) J. Exp Med. , vol.170 , pp. 1039-1044
    • Coffman, R.L.1    Lebman, D.A.2    Shrader, B.3
  • 44
    • 0028040125 scopus 로고
    • Transforming growth factor β abrogates the effects of hematopoietins on eosinophils and induces their apoptosis
    • Alam, R., P. Forsythe, S. Stafford, and Y. Fukada. 1994. Transforming growth factor β abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. J. Exp Med. 179: 1041-1045.
    • (1994) J. Exp Med. , vol.179 , pp. 1041-1045
    • Alam, R.1    Forsythe, P.2    Stafford, S.3    Fukada, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.