Brain Proton Magnetic Resonance Spectroscopy Studies in Recently Abstinent Alcoholics

Alcoholism: Clinical and Experimental Research

Volumn 19, Issue 4, 1995, Pages 1078-1082

  Martin, Peter R ^a   Gibbs, S Julian ^a   Nimmerrichter, Amanda A ^a   Riddle, William R ^a   Welch, Larry W ^a   Willcott, M Robert ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcoholic Dementia; Cerebellum; Choline; Detoxification; Magnetic Resonance Spectroscopy

Indexed keywords

ALCOHOL; CHOLINE DERIVATIVE; N ACETYLASPARTIC ACID;

ADULT; AGED; ALCOHOL ABSTINENCE; ALCOHOLISM; ALZHEIMER DISEASE; ARTICLE; BRAIN FUNCTION; BRAIN METABOLISM; CENTRAL NERVOUS SYSTEM DISEASE; CEREBELLUM; CLINICAL ARTICLE; DEMENTIA; DIAGNOSTIC IMAGING; FEMALE; HUMAN; LONGITUDINAL STUDY; MALE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ADULT; AGED; ALCOHOLISM; ASPARTIC ACID; ATROPHY; BRAIN; CEREBELLUM; CHOLINE; FEMALE; HUMAN; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGE; NEUROPSYCHOLOGICAL TESTS; REFERENCE VALUES; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029148304     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1995.tb00992.x     Document Type: Article

References (54)

1. Ethanol and the nervous system
2. The prevalence of alcoholic cerebellar atrophy: A morphometric and histologic study of an autopsy material
3. Neuropathology of alcoholism
4. The clinical versus radiological diagnosis of alcoholic cerebellar degeneration
5. Clinical assessment of cognition in alcoholism
6. Alcohol‐related dementia in the institutionalized elderly
7. Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease
8. Cholinergic‐rich brain transplants reverse alcohol‐induced memory deficits
9. Loss of cholinergic muscarinic receptors in the frontal cortex of alcohol abusers
10. Do alcoholics drink their neurons away
11. Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: A quantitative MRI study
12. Alcoholic organic brain disease: Nosology and pathophysiologic mechanisms
13. Motoric signs of CNS dysfunction associated with alcohol and cocaine withdrawal
14. Improvement of ataxia in alcoholic cerebellar atrophy through abstinence
15. Reversibility of psychological deficits in alcoholics: The interaction of aging with alcohol
16. Reversible cerebral atrophy in recently abstinent chronic alcoholics measured by computed tomography scans
17. Reversible enlargement of cerebral spinal fluid space in chronic alcoholics
18. Partially reversible cerebral atrophy and functional improvement in recently abstinent alcoholics
19. Influence of improved drinking habits on brain atrophy and cognitive performance in alcoholic patients: A 5‐year follow‐up study
20. Reversible brain shrinkage in abstinent alcoholics, measured by MRI
21. MRI study of brain changes with short‐term abstinence from alcohol
22. The reversibility of alcoholic brain damage is not due to rehydration: A CT study
23. Volumetric magnetic resonance imaging quantification of longitudinal brain changes in abstinent alcoholics
24. Spatial localization in NMR spectroscopy in vivo
25. Coupling effects in volume selective 1H spectroscopy of major brain metabolites
26. Mini‐Mental State
27. Metabolic disorders of the brain in chronic hapatic encephalopathy detected with H‐1 MR spectroscopy
28. Proton magnetic resonance spectroscopy of human brain: Applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities
29. Observations of cerebral metabolites in an animal model of acute liver failure in vivo: A 1‐H and 31‐P nuclear magnetic resonance study
30. Effects of acute hyperammonemia on cerebral amino acid metabolism and pHi in vivo, measured by 1‐H and 31‐P nuclear magnetic resonance
31. High‐resolution proton magnetic resonance spectroscopy of rabbit brain: Regional metabolite levels and postmortem changes
32. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types
33. Distribution of N‐acetylaspartate, N‐acetylaspartylglutamate, free glutamate and aspartate following complete mesencephalic transection in rat neuraxis
34. N‐acetyl‐aspartyl‐glutamate: Regional levels in rat brain and the effects of brain lesions as determined by a new HPLC method
35. Alterations in the structure of the cerebellum after long‐term ethanol consumption
36. Alcohol withdrawal causes a loss of cere‐bellar Purkinje cells in mice
37. In vivo quantification of brain metabolites by 1H‐MRS using water as an internal standard
38. Demyelination of the mammillary bodies in alcoholism
39. Cerebellum lipids in rats after chronic ethanol treatment
40. Effects of aging and alcohol on the biochemical composition of histologically normal human brain
41. Cholinergic system and memory in the rat: Effects of chronic ethanol, embryonic basal forebrain brain transplants and excitotoxic lesions of the cholinergic basal forebrain projection system
42. Impairment of behavior and acetylcholine metabolism in thiamine deficiency
43. Cerebellar and frontal hypometabolism in alcoholic cerebellar degeneration studied with positron emission tomography
44. Regional cerebral glucose utilization in chronic organic mental disorders associated with alcoholism
45. Activation of a cerebellar output nucleus during cognitive processing
46. Alzheimer's disease: Depiction of increased cerebral myo‐inositol with proton MR spectroscopy
47. Reduced brain N‐acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus‐seropositive individuals: In vivo 1‐H magnetic resonance spectroscopic imaging
48. L‐phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific 1‐glutamate receptor subtypes