Hormonal and developmental regulation of the steroidogenic acute regulatory protein

Molecular Endocrinology

Volumn 9, Issue 10, 1995, Pages 1346-1355

  Clark, Barbara J ^a   Soo, Shiu Ching ^b   Caron, Kathleen M ^b   Ikeda, Yayoi ^b   Parker, Keith L ^b   Stocco, Douglas M ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; PREGNENOLONE; REGULATOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL TRANSPORT; EMBRYO DEVELOPMENT; HORMONAL REGULATION; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; LEYDIG CELL; MITOCHONDRION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; REGULATORY MECHANISM; SEXUAL DEVELOPMENT; STEROIDOGENESIS; TESTOSTERONE SYNTHESIS;

ANIMAL; BASE SEQUENCE; CYCLIC AMP; EMBRYO; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LUTEINIZING HORMONE; MALE; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PREGNANCY; PROTEINS; RNA, MESSENGER; STEROIDS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TESTICULAR NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0029147913     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/mend.9.10.8544843     Document Type: Article

References (28)

1. Karaboyas GC, Koritz SB 1965 Identity of the site of action of 3',5'-adenosine monophosphate and adreno-cortocotropic hormone in corticosteriodogenesis in rat adrenal and beef adrenal cortex slices. Biochemistry 4: 462-468
2. Haynes RC, Koritz SB, Peron FG 1959 Influence of adenosine 3',5'-monophosphate on corticoid production by rat adrenal glands. J Biol Chem 234: 1421-1423
3. Stone D, Hechter O 1954 Studies on ACTH action in perfused bovine adrenals: The site of action of ACTH in corticosteroidogenesis. Arch Biochem Biophys 51: 457-469
4. Jefcoate CR, DiBartolomeis MJ, Williams CA, McNamara BC 1987 ACTH regulation of cholesterol movement in isolated adrenal cells. J Steroid Biochem 27: 721-729
5. Simpson ER, Waterman MR 1988 Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Annu Rev Physiol 50: 427-440
6. Ferguson JJ 1963 Protein synthesis and adrenocortico-tropin responsiveness. J Biol Chem 238: 2754-2759
7. Garren LD, Ney RL, Davis WW 1965 Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo. Proc Natl Acad Sei USA 53: 1443-1450
8. Privalle CT, Crivello JF, Jefcoate CR 1983 Regulation of intramitochondrial cholesterol transfer to side-chain cleavage cytochrome P-450 in rat adrenal gland. Proc Natl Acad Sei USA 80: 702-706
9. Jefcoate CR, McNamara BC, DiBartolemeis MJ 1986 Control of steroid synthesis in adrenal fasciculata cells. Endocr Res 12: 315-350
10. Krueger RJ, Orme-Johnson NR 1983 Acute adrenocorticotropic hormone stimulation of adrenal corticosteroidogenesis. J Biol Chem 258: 10159-10167
11. Pon LA, Hartigan JA, Orme-Johnson NR 1986 Acute ACTH Regulation of adrenal corticosteroid biosynthesis: Rapid accumulation of a phosphoprotein. J Biol Chem 261: 13309-13316
12. Epstein LF, Orme-Johnson NR 1991 Regulation of steroid hormone biosynthesis: Identification of precursors of a phosphoprotein targeted to the mitochondrion in stimulated rat adrenal cortex cells. J Biol Chem 266: 19739-19745
13. Stocco DM, Kilgore MW 1988 Induction of mitochondrial proteins in MA-10 Leydig tumour cells with human choriogonadotropin. Biochem J 249: 95-103
14. Stocco DM, Chen W 1991 Presence of identical mitochondrial proteins in unstimulated constitutive steroid-producing R 2C rat Leydig tumor and stimulated noncon-stitutive steroid-producing MA-10 mouse Leydig tumor cells. Endocrinology 128: 1918-1926
15. Stocco DM, Sodeman TC 1991 The 30-kDa mitochondrial proteins induced by hormone stimulation in MA-10 mouse Leydig tumor cells are processed from larger precursors. J Biol Chem 266: 19731-19738
16. Clark BJ, Wells J, King SR, Stocco DM 1994 Purification, cloning, and expression of a novel LH-induced mitochondrial protein from the MA-10 mouse Leydig tumor cells: Characterization of the steroidogenic acute regulatory (StAR) protein. J Biol Chem 269: 28314-28322
17. Sugawara T, Holt JA, Driscoll D, Strauss JF, Lin D, Miller WL, Patterson D, Clancy KP, Hart IM, Clark BJ, Stocco DM 1995 Human steroidogenic acute regulatory protein (StAR): Functional activity in COS cells, tissue-specific expression, mapping of the structural gene to 8p 11.2 and an expressed pseudogene to chromosome 13. Proc Natl Acad Sei USA 92: 4778-4782
18. Miller WL, Levine LS 1987 Molecular and clinical advances in congenital adrenal hyperplasia. J Pediatr 111: 1-17
19. Lin D, Gitelman SE, Saenger P, Miller WL 1991 Normal genes for the cholesterol side chain cleavage enzyme, P 450scc, in congenital lipoid adrenal hyperplasia. J Clin Invest 88: 1955-1962
20. Lin D, Sugawara T, Strauss JF, Clark BJ, Stocco DM, Saenger P, Rogol A, Miller WL 1995 Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis. Science 267: 1828-1831
21. Rice DA, Mouw AR, Bogerd AM, Parker KL 1991 A shared promoter element regulates the expression of three steroidogenic enzymes. Mol Endocrinol 5: 1552-1561
22. Luo X, Ikeda Y, Parker KL 1994 A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77: 481-490
23. Ikeda Y, Lala DS, Luo X, Kim E, Moisan M-P, Parker KL 1993 Characterization of the mouse FTZ-F 1 gene, which encodes a key regulator of steroid hydroxylase gene expression. Mol Endocrinol 7: 852-860
24. Morohashi K, Honda S, Inomata Y, Handa H, Omura T 1992 A common trans-acting binding factor, Ad 4-bind-ing protein, to the promoters of steroidogenic P 450s. J Biol Chem 267: 17913-17919
25. Ikeda Y, Shen W-H, Ingraham HA, Parker KL 1994 Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol Endocrinol 8: 654-662
26. Pon LA, Epstein LF, Orme-Johnson NR 1986 Acute cAMP Stimulation in Leydig cells: Rapid accumulation of a protein similar to that detected in adrenal cortex and corpus luteum. Endocr Res 12: 429-446
27. Waterman MR 1994 Biochemical diversity of cAMP-dependent transcription of steroid hydroxylase genes in the adrenal cortex. J Biol Chem 269: 27783-27786
28. Chomczynski P, Sacchi N 1987 Single-Step Method of RNA Isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159