Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study

Diabetes Research and Clinical Practice

Volumn 28, Issue 2, 1995, Pages 103-117

  Ohkubo, Yasuo ^a   Kishikawa, Hideki ^a   Araki, Eiichi ^a   Miyata, Takao ^a   Isami, Satoshi ^a   Motoyoshi, Sadatoshi ^a   Kojima, Yujiro ^a   Furuyoshi, Naohiko ^a   Shichiri, Motoaki ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; INSULIN;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETIC ANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS;

ALBUMINURIA; BLOOD GLUCOSE; BLOOD PRESSURE; C-PEPTIDE; CHOLESTEROL; CHOLESTEROL, HDL; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DIABETIC NEPHROPATHIES; DIABETIC NEUROPATHIES; DIABETIC RETINOPATHY; FEMALE; HUMANS; INSULIN; JAPAN; MALE; MIDDLE AGED; NEURAL CONDUCTION; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC; TIME FACTORS; TRIGLYCERIDES;

EID: 0029147687     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-8227(95)01064-K     Document Type: Article

References (39)

1. The Diabetes Control and Complications Trial (DCCT) Design and methodologic considerations for the feasibility phase
2. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
3. Effect of improved metabolic control on loss of kidney function in Type I (insulin-dependent) diabetic patients: an update of the Steno studies
4. Effect of two years of strict metabolic control on progression of incipient nephropathy in insulin-dependent diabetes
5. Diabetic retinopathy after two years of intensified insulin treatment
6. Blood glucose concentrations and progression of diabetic retinopathy: the seven year results of the Oslo study
7. Reduction of urinary albumin excretion after 4 years of continuous subcutaneous insulin infusion in insulin-dependent diabetes mellitus: the Oslo study
8. Prevention of deterioration of renal and sensory nerve function by more intensive management of insulin-dependent diabetic patients. A two-year randomized prospective study
9. Intensified conventional insulin treatment retards the microvascular complications of insulin-dependent diabetes mellitus (IDDM): the Stockholm Diabetes Intervention Study (SDIS) after 5 years
10. The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus
11. Insulin treatment regimes for Type II (non-insulin dependent) diabetes mellitus as judged by residual B-cell function
12. Diabetes Mellitus, Report of a WHO Study Group
13. Early Treatment Diabetic Retinopathy Study
14. ETDRS report No 10 Grading diabetic retinopathy from stereoscopic color fundus photographs- an extension of the modified Airlie House classification
15. ETDRS report No 12 Fundus photographic risk factors for progression of diabetic retinopathy
16. Management of diabetic renal involvement and disease
17. Effect of 1 year of near-normal blood glucose levels on retinopathy in insulin-dependent diabeties
18. Rapid tightening of blood glucose control leads to transient deterioration of retinopathy in insulin dependent diabetes mellitus: the Oslo study
19. Early detection and progression of nephropathy in patients with non-insulin-dependent diabetes
20. Prevalence of chronic complications in Japanese diabetic patients
21. Effect of antihypertensive treatment on kidney function in diabetic nephropathy
22. Improved survival in patients with diabetic nephropathy
23. Prognosis in diabetic nephropathy
24. Reversible diabetic nerve dysfunction: Structural correlates to electrophysiological abnormalities
25. Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy
26. Impact of cardiovascular risk factors on coronary heart disease and mortality among middle aged diabetic men: a general population study
27. A prospective study of maturity-onset diabetes mellitus and risk of coronary heart disease and stroke in women
28. Development of macrovascular diseases in NIDDM patients in Northern Taiwan — a 4-year follow-up study
29. Epidemiology of severe hypoglycemia in the diabetes control and complications trial
30. Weight gain associated with intensive therapy in the diabetes control and complications trial
31. Continuous subcutaneous insulin infusion (CSII) does not prevent progression of proliferative and preproliferative retinopathy
32. Influence of long-term insulin infusion pump treatment of type I diabetes on diabetic retinopathy
33. Rapid deterioration of diabetic retinopathy during treatment with continuous subcutaneous insulin infusion
34. Optimal glycemic control for diabetic patients with advanced retinopathy
35. Diabetic nephropathy in adolescence: Appearance during improved glycemic control
36. Persistent proteinuria developed after strict control of hyperglycemia in three cases of non-insulin dependent diabetes mellitus