Peroxynitrite‐Induced Cytotoxicity in PC12 Cells: Evidence for an Apoptotic Mechanism Differentially Modulated by Neurotrophic Factors

Journal of Neurochemistry

Volumn 65, Issue 4, 1995, Pages 1543-1550

  Estévez, Alvaro G ^a,b   Radi, Rafael ^c   Barbeito, Luis ^a,b   Shin, Jordan T ^d   Thompson, John A ^d,e   Beckman, Joseph S ^d,f  

^a Instituto Clemente Estable   (Uruguay)

^b Facultad de Ciencias ^*

^c DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^d Departments of Biochemistry ^*

^e University of Alabama at Birmingham ^*

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Apoptosis; Fibroblast growth factor; Nerve growth factor; PC12 cells; Peroxynitrite; Trophic factors

Indexed keywords

DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DIGOXIGENIN; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR; INSULIN; NERVE GROWTH FACTOR; NITRIC OXIDE; OXIDIZING AGENT; PEROXYNITRITE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; IMMUNOREGULATION; NEUROTROPISM; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMAL; APOPTOSIS; CELL SURVIVAL; DNA DAMAGE; DYES; FIBROBLAST GROWTH FACTOR 2; NERVE GROWTH FACTORS; NEURONS; NITRATES; PC12 CELLS; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029146273     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1995.65041543.x     Document Type: Article

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