Osteopontin Overview

Annals of the New York Academy of Sciences

Volumn 760, Issue 1, 1995, Pages 1-5

  RODAN, GIDEON A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; OSTEOPONTIN; PHOSPHOPROTEIN; VITRONECTIN;

BONE REMODELING; CELL ADHESION; CONFERENCE PAPER; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; PROTEIN LOCALIZATION;

EID: 0029146110     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1995.tb44614.x     Document Type: Article

References (38)

1. Identification of osteopontin in isolated rabbit osteoclasts
2. 2HS‐glycoprotein) proteins in rat bone
3. Heterogeneity of osteopontin expression among nephrons in mouse kidneys and enhanced expression in sclerotic glomeruli
4. Osteopontin expression in angiotensin II‐induced tubulointerstitial nephritis
5. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques
6. Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques
7. Osteopontin mRNA is expressed by smooth muscle‐derived foam cells in human atherosclerotic lesions of the aorta
8. High expression of genes for calcification‐regulating proteins in human atherosclerotic plaques
9. Molecular cloning and characterization of 2B7, a rat mRNA which distinguishes smooth muscle cell phenotypes in vitro and is identical to osteopontin (secreted phosphoprotein 1, 2ar)
10. 44‐kDal bone phosphoprotein (osteopontin) antigenicity at ectopic sites in newborn rats: kidney and nervous tissues
11. Distribution of expression of 2AR (osteopontin) in the embryonic mouse inner ear revealed by in situ hybridization
12. Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces
13. Normal rat kidney cells secrete both phosphorylated and nonphosphorylated forms of osteopontin showing different physiological properties
14. Osteopontin: its transglutaminase‐catalyzed posttranslational modifications and cross‐linking to fibronectin
15. Differential regulation of the 55 and 44 kDa forms of secreted phosphoprotein (SPP‐1, osteopontin) in normal and transformed rat bone cells by osteotropic hormones, growth factors and tumor promoter
16. Induction of osteopontin mRNA expression during activation of murine NK cells
17. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro
18. Definition of a specific interaction between the early T lymphocyte activation (Eta‐1) protein and murine macrophages in vitro and its effect upon macrophages in vivo
19. Reduced malignancy of ras‐transformed NIH 3T3 cells expressing antisense osteopontin mRNA
20. Specific reduction in osteopontin synthesis by antisense RNA inhibits the tumorigenicity of transformed Rat1 fibroblasts
21. Cell attachment activity of the 44 kilodalton bone phosphoprotein is not restricted to bone cells
22. The osteoclast functional antigen implicated in the regulation of bone resorption is biochemically related to the vitronectin receptor
23. Monoclonal antibodies against osteoclasts inhibit bone resorption in vitro
24. Dephosphorylation of osteopontin and bone sialoprotein by osteoclastic tartrate‐resistant acid phosphatase
25. 3 for angiogenesis
26. 3‐mediated endothelial cell migration is triggered through distinct signaling mechanisms
27. Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation
28. Adhesive properties of osteopontin: regulation by a naturally occurring thrombin‐cleavage in close proximity to the GRGDS cell‐binding domain
29. Integrins: versatility, modulation, and signaling in cell adhesion
30. 3 integrin stimulates immediate cell signals in osteoclasts
31. 2+]i in rat osteoclasts and mouse‐derived osteoclast‐like cells
32. Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium
33. Increased intracortical remodeling following fatigue damage
34. Osteoblastic Cells
35. Ostopontin, a transformation‐associated cell adhesion phosphoprotein, is induced by 12‐O‐tetradecanoylphorbol 13‐acetate in mouse epidermis
36. The mouse osteopontin gene. Expression in monocytic lineages and complete nucleotide sequence
37. Structural and functional studies of the early T lymphocyte activation (Eta‐1) gene
38. Developmental expression of osteopontin (OPN) mRNA in rat tissues: evidence for a role for OPN in bone formation and resorption