Synthesis and Anticonvulsant Activity of N-Benzylpyrrolo[2,3-d]-, -pyrazolo[3,4-d]-, and -triazolo[4,5-d]pyrimidines: Imidazole Ring-Modified Analogues of 9-(2-Fluorobenzyl)-6-(methylamino)-9H-purine

Journal of Medicinal Chemistry

Volumn 38, Issue 19, 1995, Pages 3884-3888

  Kelley, James L ^a   Davis, Ronda G ^a   McLean, Ed W ^a   Glen, Robert C ^b   Soroko, Francis E ^c   Cooper, Barrett R ^c  

^a Burroughs Wellcome Co   (United States)

^b Research Triangle Park ^*  (United States)

^c WELLCOME RESEARCH LABORATORIES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYLPYRROLO[2,3 D]PYRIMIDINE DERIVATIVE; 9 (2 FLUOROBENZYL) 6 N METHYLADENINE; ANTICOAGULANT AGENT; BW 78U79; N BENZYLPYRAZOLO[3,4 D]PYRIMIDINE DERIVATIVE; N BENZYLTRIAZOLO[4,5 D]PYRIMIDINE DERIVATIVE; PHENYTOIN; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; MALE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; ORAL DRUG ADMINISTRATION; RAT; SEIZURE; STRUCTURE ACTIVITY RELATION;

ANIMAL; ANTICONVULSANTS; CONVULSIONS; MALE; PURINES; PYRIMIDINES; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029146072     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00019a019     Document Type: Note

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