A comparison of the radiosensitivity of lymphocytes from normal donors, cancer patients, individuals with ataxia-telangiectasia (a-t) and a-t heterozygotes

International Journal of Radiation Biology

Volumn 68, Issue 2, 1995, Pages 197-203

  West, C M L ^a   Elyan, S A G ^a   Berry, P ^a   Cowan, R ^a   Scott, D ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ATAXIA TELANGIECTASIA; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; PRIORITY JOURNAL; RADIOSENSITIVITY;

ATAXIA TELANGIECTASIA; BREAST NEOPLASMS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; HETEROZYGOTE; HUMAN; LYMPHOCYTES; RADIATION TOLERANCE; SUPPORT, NON-U.S. GOV'T;

EID: 0029145291     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553009514551101     Document Type: Article

References (21)

1. Prediction of normal-tissue tolerance to radiotherapy from in vitro cellular radiation sensitivity
2. 0) T-lymphocytes, T-lymphocyte lines, lymphoblastoid cell lines and fibroblasts from normal donors, from ataxia-telangiectasia patients and from ataxia-telangiectasia heterozygotes
3. A cellular description of the repair defect in ataxia telangiectasia
4. Nuclear lysate sedimentation measurements of peripheral blood lymphocytes from radiotherapy patients
5. Use of low dose-rate irradiation to measure the intrinsic radiosensitivity of human T-lymphocytes
6. Use of an internal standard in comparative measurements of the intrinsic radiosensitivity of human T-lymphocytes
7. Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients
8. Intrinsic radiosensitivity of normal human fibroblasts and lymphocytes after high and low dose-rate irradiation
9. Determination of the proportion of persons in the population-at-large who exhibit abnormal sensitivity to ionizing radiation
10. Evidence for a positive correlation between in vitro radiosensitivity of normal human skin fibroblasts and the occurrence of subcutaneous fibrosis after radiotherapy
11. Abnormal radiosensitivity of lymphocytes from breast cancer patients with excessive normal tissue damage after radiotherapy: chromosome aberrations after low dose rate irradiation
12. Is interindividual variation of cellular radiosensitivity real or artifactual?
13. Use of rapid tests of cellular radiosensitivity in radiotherapeutic practice
14. Detection of cancer-prone individuals using cytogenetic response to X-rays
15. Identification of A-T heterozygotes
16. Cytogenetics of ataxia-telangiectasia
17. Cytogenic characterization of ataxia telangiectasia heterozygotes using lymphoblastoid cell lines and chronic γ-irradiation
18. Assessment of chronic radiosensitivity as an in vitro assay for identification of ataxia telangiectasia
19. Review article. Intrinsic radiosensitivity as a predictor of patient response to radiotherapy
20. Intrinsic radiosensitivity as a predictor of patient response to radiotherapy
21. Normal cell radiosensitivity: clinical application in predicting response to radiotherapy and cancer predisposition