Mechanisms of thrombin receptor agonist specificity: Chimeric receptors and complementary mutations identify an agonist recognition site

Journal of Biological Chemistry

Volumn 270, Issue 37, 1995, Pages 21619-21625

  Nanevicz, Tania ^a   Ishii, Maki ^a,b   Wang, Ling ^a,b   Chen, Mian ^a,b   Chen, Ji ^a   Turck, Christoph W ^a   Cohen, Fred E ^a,c   Coughlin, Shaun R ^a,b,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Daiichi Research Center   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d AMERICAN HEART ASSOCIATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; CALCIUM 45; GLUTAMINE; LEUCINE; PHENYLALANINE; THROMBIN; THROMBIN RECEPTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHIMERA; GENE MUTATION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; XENOPUS;

AMINO ACID SEQUENCE; ANIMAL; ARGININE; BINDING SITES; CHIMERIC PROTEINS; COMPARATIVE STUDY; FEMALE; HUMAN; KINETICS; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; OOCYTES; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, THROMBIN; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; XENOPUS;

EID: 0029143923     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.37.21619     Document Type: Article

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