Increased expression of CD44v6 and CD44v3 in ulcerative colitis but not colonic Crohn's disease

The Lancet

Volumn 345, Issue 8959, 1995, Pages 1205-1209

  Rosenberg, W M C ^a   Jackson, D G ^a   Trowell, J M ^a   Bell, J I ^a   Prince, C ^a   Chapman, R W ^a   Jewel, D P ^a   Kaklamanis, L ^a   Fox, S B ^a   Simmons, D L ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HERMES ANTIGEN; MONOCLONAL ANTIBODY;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; COLITIS; COLON; COLON BIOPSY; COLON CROHN DISEASE; COLON MUCOSA; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOPATHOGENESIS; INTESTINE CRYPT; LIVER; MALE; PRIORITY JOURNAL; SMALL INTESTINE; ULCERATIVE COLITIS;

EID: 0029138696     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(95)91991-0     Document Type: Article

References (20)

1. A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family
2. Genomic structue of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
3. A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps
4. CD44—a molecule involved in leukocyte adherence and T-cell activation
5. CD44 and its interactions with the extracellular matrix
6. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells.
7. Distinct effects of two CD44 isoforms on tumour growth in vivo
8. A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps
9. Normal human tissues, in addition to tumours, express multiple different CD44 isoforms
10. Non-specific inflammatory bowel disease: one disease or two?
11. The prevalence of inflammatory bowel disease in relatives of patients with Crohn's disease
12. Multifocal gastrointestinal infarction
13. Expression and modulation of CD44 variant isoforms in humans
14. A tissue-specific endothelial cell molecule involved in lymphocyte homing
15. α4β7 integrin mediates lymphocyte binding to the vascular addressin MAdCAM-1
16. A family of β7 integrins on human mucosal lymphocytes
17. 7 integrin
18. Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon
19. CD44 isoforms containing exon v3 are responsible for the presentation of heparin-binding growth factor
20. Attenuation of colitis in the cotton-top tamarin by anti-α4 integrin monoclonal antibody