Benzylphthalimides and Phenethylphthalimides with Thalidomide-Like Activity on the Production of Tumor Necrosis Factor α

Biological and Pharmaceutical Bulletin

Volumn 18, Issue 9, 1995, Pages 1228-1233

  Sasaki, Keizo ^a   Shibata, Yoshihiro ^a   Hashimoto, Yuichi ^a   Iwasaki, Shigeo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

biological response modifier; phthalimides; structure activity relationship; thalidomide; tumornecrosis factor

Indexed keywords

4,5,6,7 TETRAFLUORO 2 PHENETHYL 1H ISOINDOLE 1,3 DIONE; N BENZYLPHTHALIMIDE DERIVATIVE; N PHENETHYLPHTHALIMIDE DERIVATIVE; PHTHALIMIDE DERIVATIVE; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG CONFORMATION; DRUG POTENCY; HUMAN; HUMAN CELL; IMMUNOREGULATION; LEUKEMIA CELL LINE; PROTEIN SYNTHESIS REGULATION; STRUCTURE ACTIVITY RELATION;

HL-60 CELLS; HUMAN; PHTHALIMIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRADECANOYLPHORBOL ACETATE; THALIDOMIDE; TUMOR NECROSIS FACTOR;

EID: 0029134797     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.18.1228     Document Type: Article

References (23)

1. Kelsey F.O., Teratology, 38, 221—226 (1988).
2. Hashimoto Y., Chemistry Today, No. 283, 38—44 (1994).
3. Randall T., J. Am. Med. Assoc., 263, 1467—1468 (1990).
4. Kaplan G., Immunobiology, 191, 564—568 (1994).
5. Feldmann R., Salomon D., Saurat J. -H., Dermatology, 189, 425—427 (1994).
6. Makonkawkeyoon S., Limson-Pombre R.N.R., Moreira A.L., Schauf V., Kaplan G., Proc. Natl. Acad. Sci. U.S.A., 90, 5974—5978 (1993).
7. Siadak M., Sullivan K. M., Blood Rev., 8, 154—160 (1994).
8. Carswell E. A., Old L. J., Kassel R. L., Green S., Foire N., Williamson B., Proc. Natl. Acad. Sci. U.S.A., 72, 3666—3670 (1975).
9. Sampip E. P., Sarno E. N., Galilly R., Conn Z. A., Kaplan G., J. Exp. Med., 173, 699—703 (1991).
10. Nogueira A. C., Neubert R., Helge H., Neubert D., Life Sci., 55, 77—92 (1994).
11. Hashimoto Y., Kagaku To Seibutsu, 32, 604—608 (1994).
12. Boussiotis V.A., Nadler L.M., Strominger J.L., Goldfeld A.E., Proc. Natl. Acad. Sci. U.S.A., 91, 7007—7011 (1994).
13. Debs R. J., fucks H. J., Phillip R., Brunette E. N., Duzgunes N., Shellito J. E., Liggitt D., Patton J., Cancer Res., 50, 375-380 (1990).
14. Komori A., Yatsunami J., Suganuma M., Okabe M., Sakai A., Sasaki K., Fujiki H., Cancer Res., 53, 1982—1985 (1993).
15. D'Amato R.J., Loughnan M.S., Flynn E., Folkman J., Proc. Natl. Acad. Sci. U.S.A., 91, 4082—4085 (1994).
16. Manda T., Nishigaki F., Hemmi H., Ishida N., Cancer Res., 48, 4250—4255 (1988).
17. Nishimura K., Hashimoto Y., Iwasaki S., Biochem. Biophys. Res. Commun., 199, 455—460 (1994).
18. Nishimura K., Hashimoto Y., Iwasaki S., Chem. Pharm. Bull., 42, 1157—1159 (1994).
19. Hashimoto Y., Farumasia, 30, 1276—1280 (1994).
20. Shibata Y., Shichita M., Sasaki K., Nishimura K., Hashimoto Y., Iwasaki S., Chem. Pharm. Bull., 43, 177—179 (1995).
21. Shibata, Y., Sasaki K., Nishimura K., Hashimoto Y., Iwasaki S., Biol. Pharm. Bull., 17, 1532—1534 (1994).
22. Shibata Y., Sasaki K., Hashimoto Y., Iwasaki S., Biochem. Biophys. Res. Commun., 205, 1992—1997 (1994).
23. Sasaki K., Shibata Y., Nishimura K., Hashimoto Y., Iwasaki S., Biol. Pharm. Bull., 17, 1313—1315 (1994).