Neuronal Nicotinic Receptor Subtypes

Annals of the New York Academy of Sciences

Volumn 757, Issue 1, 1995, Pages 100-116

  LINDSTROM, JON ^a   ANAND, RENÉ ^a   PENG, XIAO ^a   GERZANICH, VOLODYMYR ^a   WANG, FAN ^a   LI, YUEBTNG ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; ION CHANNEL; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CHROMOSOMAL LOCALIZATION; LEARNING; MEMORY; MULTIGENE FAMILY; NEUROMUSCULAR SYNAPSE; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RECEPTOR BINDING;

EID: 0029133310     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1995.tb17467.x     Document Type: Article

References (96)

1. Ligand‐gated ion channels in the brain: The amino acid receptor superfamily
2. Receptor classes and the transmitter‐gated ion channels
3. The molecular biology of mammalian glutamate receptor channels
4. Mortality from tobacco in developed countries: Indirect estimation from national vital statistics
5. Nicotine acetylcholine receptors
6. Structure of nicotinic acetylcholine receptors
7. The diversity of neuronal nicotinic acetylcholine receptors
8. Epitope mapping of antibodies to acetylcholine recepturs
9. Antisera against an α3 fusion protein bind to ganglion but not to brain nicotinic acetylcholine receptors
10. Brain α‐bungarotoxin‐binding protein cDNAs and mAbs reveal subtypes of this branch of the ligand‐gated ion channel superfamily
11. Reporter epitopes: A novel approach to examine transmembrane topology of integral memhrane proteins applied to the α1 subunit of the nicotinic acetylcholine receptor
12. Chromosomal localization of seven neuronal nicotinic receptor subunit genes in humans
13. Molecular cloning and chromosomal localization of the human α7 nicotinic receptor subunit gene (CHRNA7)
14. Cloning and sequence of the human α7 nicotinic acetylcholine receptor
15. Linkage disequilibrium study of RFLPs detected at the human muscle nicotinic acetylcholine receptor subunit genes
16. Assignment of the human nicotinic acetylcholine receptor genes: The α and δ subunit genes to chromosome 2 and the β subunit gene to chromosome 17
17. Mapping of multiple subunits of the neuronal nicotinic acetylcholine receptor to chromosome 15 in man and chromosome 9 in mouse
18. The regulation of acetylcholine receptor expression in mammalian muscle
19. The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti‐MIR antibodies
20. Determination of amino acids critical to the main immunogenic region of intact acetylcholine receptors by in vitro mutagenesis
21. Mutational analysis of muscle nicotinic acctylcholine receptor subunit assembly
22. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor
23. The N‐terminal domains of acetyleholine receptor subunits contain recognition signals for the initial steps of receptor assembly
24. Assembly of Torpedo acetylcholine receptor in Xenopus oocytes
25. Nicotinic acetylcholine receptor at 9Å resolution
26. Acetylcholine receptor channel structure probed in cysteine‐substitution mutants
27. Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors
28. The nicotinic receptor genes
29. Purification and characterization of a nicotinic acetylcholinc receptor from rat brain
30. Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies
31. Differential expression of nicotinic acetylcholine receptor subtypes in brain and retina
32. Purification and characterization of a nicotinic acetylcholine receptor from chick brain
33. Structurally different neuronal nicotinic acetylcholine receptor subtypes purified and characterized using monoclonal antibodies
34. Affinity purification of nicotinic acetylcholine receptor from rat brain
35. Phosphorylation of rat brain nicotinic acetylcholine receptor by CAMP‐dependent protein kinase in vitro
36. Neuronal nicotinic acetylcholine receptor p subunit is coded for by the cDNA clone α4
37. cDNA clones coding for the structural subunit of a chicken brain nicotinic acetylcholine receptor
38. A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is upregulated by chronic nicotine treatment
39. The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain
40. Structural and pharmacological characterization of the major brain nicotinic acetylcholine receptor subtype stably expressed in mouse fibroblasts
41. Physostigmine and galanthamine reveal the presence of the novel binding site on the α4β2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells. J. Pharmacol. Exp
42. Chicken neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure
43. Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor
44. Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system
45. 125I] α‐bungarotoxin
46. Immunocytochernical localization of a neuronal nicotinic receptor: The β2 subunit
47. Cholinoceptive neurons in the retina of the chick: An immunohistochemical study of the nicotinic acetylcholine receptors
48. Neurons of the chick brain and retina expressing both α‐bungarotoxin‐sensitive and α‐bungarotoxin‐insensitive nicotinic acetylcholine receptors: An immunohistochemical analysis
49. 125I‐α‐bungarotoxin‐labeled nicotinic receptors in the interpeduncular nucleus of rats. II. Effects of habenular deafferentation
50. Immunohistochemical localization of nicotinic acetylcholine receptor subunits in the mesencephalon and diencephalon of the chick (Gallus gallus)
51. Stereoselective nicotine‐induced release of dopamine from striatal synaptosomes: Concentration dependencr and repetitive stimulation
52. 3H dopamine release from mouse striatal synaptosomes
53. Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment
54. Nicotine‐induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover
55. Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes
56. Mapping of surface structures on Electrophorus acetylcholine receptor using monoclonal antibodies
57. Nucleotide sequence of the human nicotinic acetylcholine receptor β2 subunit gene
58. A shared antigenic determinant between the Electrophorus acetylcholine receptor and a synaptic component on chick ciliary ganglion neurons
59. Surface and intracellular distribution of a putative neuronal nicotinic acetylcholine receptor
60. The ultrastructural localization of α‐bungarotoxin binding sites in relation to synapses on chick ciliary ganglion neurons
61. Brain and muscle nicotinic acetylcholine receptors are different hut homologous proteins
62. Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium
63. Human α7 acetylcholine receptor: Cloning of the α7 subunit from the SH‐SY5Y cell line and determination of pharmacological properties of native receptors and functional α7 homomers expressed in Xenopus oocytes. Mol
64. Epitope mapping of polyclonal and monoclonal antibodies against two α‐bungarotoxin binding subunits from neuronal nicotinic receptors
65. Identification of sequence segments forming the α‐bungarotoxin binding sites on two nicotinic acetylcholine receptor α subunits from the avian brain
66. Three subtypes of α‐bungarotoxin sensitive nicotinic acetylcholine receptors are expressed in chick retina
67. Purification and characterization of an α‐bungarotoxin receptor that forms a functional nicotinic channel
68. Antipeptide specific antibodies for the characterization of different a subunits of α‐bungarotoxin binding acetylcholine receptors present in chick optic lobe
69. A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homomeric channel blocked by α‐bungarotoxin
70. Pharmacological characterization of α‐bungarotoxin sensitive AChRs immunoisolated from chick retina: Contrasting properties of α7 and α8 subunit‐containing subtypes
71. TE671 cells express an abundance of a partially mature acetylcholine receptor α subunit which has characteristics of an assembly intermediate
72. Pharmacological properties of immunoisolated neuronal nicotinic receptors
73. Perfection of a synaptic receptor: Kinetics and energetics of the acetylcholine receptor
74. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic
75. Chimaeric nicotinic‐serotonergic receptor combines distinct ligand binding and channel specificities
76. Homomers of α8 subunits of nicotinic receptors functionally expressed in Xenoprrs oocytes exhibit similar channel but contrasting binding site properties compared to α7 homomers. Mol
77. Homomeric and native α7 acetylcholine receptors exhibit remarkably similar but nonidentical pharmacological properties suggesting that the native receptor is a heteromeric protein complex
78. Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors
79. Nicotinic antagonists enhance process outgrowth by rat retinal ganglion cells in culture
80. Neuronal acetylcholine receotors that bind α‐bungarotoxin with high affinity function as ligand‐gated ion channels
81. Neuronal acetylcholine receptors that bind α‐bungarotoxin mediate neurite retraction in a calcium‐dependent manner
82. Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons
83. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes
84. Brief‐lifetime, fast‐inactivating ion channels account for the α‐bungarotoxin‐sensitive nicotinic response in hippocampal neurons
85. Immunocytochemical localization of the α7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system
86. GABA‐like immunoreactive cells containing nicotinic acetylcholine receptors in the chick retina
87. Bipolar cells of the chick retina containing α‐bungarotoxin‐sensitivc nicotinic acetylcholine receptors
88. Differential development of α‐bungarotoxin‐sensitive and α‐bungarotoxin‐insensitive nicotinic acetylcholine receptors in the chick retina
89. Cholinergic inhibition of short (outer) hair cells of the chick's cochlea
90. A novel cholinergic receptor mediates inhibition of chick cochlear hair cells
91. α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells